Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Albert K Lee"'
Publikováno v:
eLife, Vol 11 (2022)
A wide range of techniques in neuroscience involve placing individual probes at precise locations in the brain. However, large-scale measurement and manipulation of the brain using such methods have been severely limited by the inability to miniaturi
Externí odkaz:
https://doaj.org/article/615fea16382242fd9637dbd45f328a64
Autor:
Claudia Böhm, Albert K Lee
Publikováno v:
eLife, Vol 9 (2020)
The prefrontal cortex (PFC)’s functions are thought to include working memory, as its activity can reflect information that must be temporarily maintained to realize the current goal. We designed a flexible spatial working memory task that required
Externí odkaz:
https://doaj.org/article/f5406b07c5b44e99bec9ba20042d35fe
Publikováno v:
eLife, Vol 6 (2017)
The hippocampus is critical for producing stable representations of familiar spaces. How these representations arise is poorly understood, largely because changes to hippocampal inputs have not been measured during spatial learning. Here, using intra
Externí odkaz:
https://doaj.org/article/8769b85aa32c4013812bc18d8bafed3e
Publikováno v:
Nature Neuroscience. 26:131-139
Daily experience suggests that we perceive distances near us linearly. However, the actual geometry of spatial representation in the brain is unknown. Here we report that neurons in the CA1 region of rat hippocampus that mediate spatial perception re
The hippocampus is critical for recollecting and imagining experiences. This is believed to involve voluntarily drawing from hippocampal memory representations of people, events, and places, including the hippocampus’ map-like representations of fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58670cfe4276145e9c241ac2b25eb6e5
https://doi.org/10.1101/2023.04.07.536077
https://doi.org/10.1101/2023.04.07.536077
Autor:
Claudia Böhm, Albert K. Lee
Individual neurons in prefrontal cortex – a key brain area involved in cognitive functions – are selective for variables such as space or time, as well as more cognitive aspects of tasks, such as learned categories. Many neurons exhibit mixed sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81518df3d3b3f095761c559619fb8122
https://doi.org/10.1101/2023.01.16.524214
https://doi.org/10.1101/2023.01.16.524214
Place cells are believed to organize memory across space and time, inspiring the idea of the cognitive map. Yet unlike the structured activity in the associated grid and head-direction cells, they remain an enigma: their responses have been difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d3b11a6abf6e1d3e6a7dddcccfb758
https://doi.org/10.1101/2021.11.20.469406
https://doi.org/10.1101/2021.11.20.469406
Publikováno v:
Nature neuroscience.
Daily experience suggests that we perceive distances near us linearly. However, the actual geometry of spatial representation in the brain is unknown. Here we report that neurons in the CA1 region of rat hippocampus that mediate spatial perception re
Autor:
John O'Callaghan, Maxime Beau, Fabian Kloosterman, Abraham Z. Vollan, Anna Lebedeva, Michael Häusser, Susu Chen, Joshua T. Dudman, John O'Keefe, Cagatay Aydin, Timothy D. Harris, Albert K. Lee, Nicholas A. Steinmetz, Jan Putzeys, Kenneth D. Harris, Rik van Daal, Carolina Mora-Lopez, Matteo Carandini, Zhiwen Ye, Marius Pachitariu, Karel Svoboda, Marius Bauza, Jennifer Colonell, Dimitar Kostadinov, Claudia Böhm, Martijn Broux, Edvard I. Moser, Michael S. Okun, B. Dutta, Alfonso Renart, Adam W. Hantman, Richard J. Gardner, Shiwei Wang, Sebastian Haesler, Bill Karsh, Britton Sauerbrei, Jai Bhagat, Junchol Park, Marleen Welkenhuysen
Publikováno v:
Science
Recording many neurons for a long time The ultimate aim of chronic recordings is to sample from the same neuron over days and weeks. However, this goal has been difficult to achieve for large populations of neurons. Steinmetz et al. describe the deve