Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Albert J. Pedroza"'
Autor:
Alex R. Dalal, MD, Albert J. Pedroza, MD, Aravind Krishnan, MD, Yan Min, MD, MS, Emily Tognozzi, PA-C, Nobu Yokoyama, MD, Ken Nakamura, MD, Olivia R. Mitchel, BS, Michael Baiocchi, PhD, Y. Joseph Woo, MD, John W. MacArthur, MD, Michael P. Fischbein, MD, PhD
Publikováno v:
JTCVS Open, Vol 13, Iss , Pp 9-19 (2023)
Objective: To evaluate the effect of perioperative allogeneic packed red blood cell (RBC) transfusion during aortic root replacement. Method: We reviewed patients undergoing aortic root replacement at our institution between March 2014 and April 2020
Externí odkaz:
https://doaj.org/article/07327f7dcdd3474bb97c01fa04c96be2
Autor:
Hye Sook Shin, Akshara Thakore, Yuko Tada, Albert J. Pedroza, Gentaro Ikeda, Ian Y. Chen, Doreen Chan, Kevin J. Jaatinen, Shin Yajima, Eric M. Pfrender, Masashi Kawamura, Phillip C. Yang, Joseph C. Wu, Eric A. Appel, Michael P. Fischbein, YJoseph Woo, Yasuhiro Shudo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Many cell-based therapies are challenged by the poor localization of introduced cells and the use of biomaterial scaffolds with questionable biocompatibility or bio-functionality. Endothelial progenitor cells (EPCs), a popular cell type used
Externí odkaz:
https://doaj.org/article/20ab15817ad2445c8d8fd81a36008cce
Autor:
Cristiana Iosef, Albert J. Pedroza, Jason Z. Cui, Alex R. Dalal, Mamoru Arakawa, Yasushi Tashima, Tiffany K. Koyano, Grayson Burdon, Samantha M. P. Churovich, Joshua O. Orrick, Mitchel Pariani, Michael P. Fischbein
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1 gene that produces wide disease phenotypic variability. The lack of ample genotype–phenotype correlation hinders translational study development aimed at
Externí odkaz:
https://doaj.org/article/5f51d52d33394a82b68928fa4c927f13
Autor:
Yasushi Tashima, Hao He, Jason Z. Cui, Albert J. Pedroza, Ken Nakamura, Nobu Yokoyama, Cristiana Iosef, Grayson Burdon, Tiffany Koyano, Atsushi Yamaguchi, Michael P. Fischbein
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 20 (2020)
Background Male patients with Marfan syndrome have a higher risk of aortic events and root dilatation compared with females. The role androgens play during Marfan syndrome aneurysm development in males remains unknown. We hypothesized that androgens
Externí odkaz:
https://doaj.org/article/350c3d55cf2d4cf18ea4784b97464174
Autor:
Tetsuya Sato, Mamoru Arakawa, Yasushi Tashima, Eitoshi Tsuboi, Grayson Burdon, Jeffrey Trojan, Tiffany Koyano, Young‐Nam Youn, Kiril Penov, Albert J. Pedroza, Mohammad Shabazzi, Itai Palmon, Marie Noel Nguyen, Andrew J. Connolly, Atsushi Yamaguchi, Michael P. Fischbein
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 21 (2018)
Background Statins reduce aneurysm growth in mouse models of Marfan syndrome, although the mechanism is unknown. In addition to reducing cholesterol, statins block farnesylation and geranylgeranylation, which participate in membrane‐bound G‐prote
Externí odkaz:
https://doaj.org/article/2fd36db5b2c641788e5c50564d7f9118
Autor:
Albert J. Pedroza, Alex R. Dalal, Rohan Shad, Nobu Yokoyama, Ken Nakamura, Olivia Mitchel, Casey Gilles, William Hiesinger, Michael P. Fischbein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:971-978
Background: Smooth muscle cell (SMC) phenotypic reprogramming toward a mixed synthetic-proteolytic state is a central feature of aortic root aneurysm in Marfan syndrome (MFS). Previous work identified Klf4 as a potential mediator of SMC plasticity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44a09ab2ecf7787e173f307b9166755e
https://doi.org/10.1161/atvbaha.122.318509
https://doi.org/10.1161/atvbaha.122.318509
Autor:
Albert J. Pedroza, Alex R. Dalal, Rohan Shad, Nobu Yokoyama, Ken Nakamura, Paul Cheng, Robert C. Wirka, Olivia Mitchel, Michael Baiocchi, William Hiesinger, Thomas Quertermous, Michael P. Fischbein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:1154-1168
Background: Aortic root smooth muscle cells (SMC) develop from both the second heart field (SHF) and neural crest. Disparate responses to disease-causing Fbn1 variants by these lineages are proposed to promote focal aortic root aneurysm formation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be331ce48a9c856556936d2b3bf4c8a8
https://doi.org/10.1161/atvbaha.122.317381
https://doi.org/10.1161/atvbaha.122.317381
Autor:
Anita Kaw, Albert J. Pedroza, Abhijnan Chattopadhyay, Amelie Pinard, Dongchuan Guo, Kaveeta Kaw, Zhen Zhou, Rohan Shad, Michael P. Fischbein, Callie S. Kwartler, Dianna M. Milewicz
Publikováno v:
Journal of Molecular and Cellular Cardiology. 171:102-104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f552c7454511ace1e1c6af4f36312f5
https://doi.org/10.1016/j.yjmcc.2022.07.004
https://doi.org/10.1016/j.yjmcc.2022.07.004
Autor:
Albert J. Pedroza, Alex R. Dalal, Aravind Krishnan, Nobu Yokoyama, Ken Nakamura, Emily Tognozzi, Y. Joseph Woo, John W. Macarthur, Michael P. Fischbein
Publikováno v:
Seminars in Thoracic and Cardiovascular Surgery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07e85950e534d9c4ff83acbb43722d79
https://doi.org/10.1053/j.semtcvs.2023.02.001
https://doi.org/10.1053/j.semtcvs.2023.02.001
Autor:
Alex R. Dalal, Albert J. Pedroza, Aravind Krishnan, Yan Min, Emily Tognozzi, Nobu Yokoyama, Ken Nakamura, Olivia R. Mitchel, Michael Baiocchi, Y. Joseph Woo, John W. MacArthur, Michael P. Fischbein
Publikováno v:
JTCVS Open
OBJECTIVE: To evaluate the effect of perioperative allogeneic packed red blood cell (RBC) transfusion during aortic root replacement. METHOD: We reviewed patients undergoing aortic root replacement at our institution between March 2014 and April 2020
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089302c967c8bb470cff544d46ebdea1
https://europepmc.org/articles/PMC10091283/
https://europepmc.org/articles/PMC10091283/
