Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Albert J. Dietz"'
Autor:
Albert J. Dietz, Robert Townsend, Christopher Lademacher, Donna Kowalski, Amit Desai, Helene Pearlman, Shahzad Akhtar, Takao Yamazaki
Publikováno v:
Clinical Pharmacology in Drug Development. 6:86-92
This phase 1 trial evaluated pharmacokinetic and pharmacodynamic interactions between the novel triazole antifungal agent isavuconazole and warfarin in healthy adults. Multiple doses of isavuconazole were administered as the oral prodrug, isavuconazo
Autor:
Helene Pearlman, Amit Desai, Kenneth C. Lasseter, Christopher Lademacher, Christine Hale, Donna Kowalski, Shahzad Akhtar, Anne Schmitt-Hoffmann, Albert J. Dietz, Robert Townsend, Diane Rammelsberg, Takao Yamazaki
Publikováno v:
Clinical Pharmacology in Drug Development. 6:44-53
This report describes the phase 1 trials that evaluated the metabolism of the novel triazole antifungal isavuconazole by cytochrome P450 3A4 (CYP3A4) and isavuconazole's effects on CYP3A4-mediated metabolism in healthy adults. Coadministration of ora
Publikováno v:
Clinical Pharmacology in Drug Development. 3:25-33
Albaconazole is a triazole antifungal agent discovered at Palau Pharma SA (Barcelona, Spain) and currently being developed for the treatment of fungal infections of the nails. This randomized, double-blind, placebo-controlled, phase 1 study evaluated
Autor:
Amit, Desai, Takao, Yamazaki, Albert J, Dietz, Donna, Kowalski, Christopher, Lademacher, Helene, Pearlman, Shahzad, Akhtar, Robert, Townsend
Publikováno v:
Clinical Pharmacology in Drug Development
This phase 1 trial evaluated pharmacokinetic and pharmacodynamic interactions between the novel triazole antifungal agent isavuconazole and warfarin in healthy adults. Multiple doses of isavuconazole were administered as the oral prodrug, isavuconazo
Publikováno v:
Cancer Management and Research
Jay W Mason,1 Thomas E Moon,2 Erin O’Boyle,3 Albert Dietz41Department of Medicine, University of Utah, Salt Lake City, UT, 2Tarizona eHealth Services, Inc., San Carlos, CA, 3AP Pharma, Redwood City, CA, 4Spaulding Clinical Research, West Bend, WI,
Autor:
Donna Dorozinsky, Susana R. K. de Dennis, Mariana Kiefer-Johnson, Albert J. Dietz, Gary L. Steinman, William L. Hirschhorn, Howard Uderman
Publikováno v:
Drug Information Journal. 31:751-757
Clinical Pharmacology Units (CPUs) are a special class of clinical research units for investigating the pharmacokinetic, pharmacodynamic, and toxicologic properties of drugs in man. The Association of Clinical Pharmacology Units (ACPU) is a national
Publikováno v:
Clinical pharmacology in drug development. 3(1)
Albaconazole is a triazole antifungal agent discovered at Palau Pharma SA (Barcelona, Spain) and currently being developed for the treatment of fungal infections of the nails. This randomized, double-blind, placebo-controlled, phase 1 study evaluated
Publikováno v:
Journal of Clinical Oncology. 31:e20539-e20539
e20539 Background: This study evaluated effects of subcutaneous (SC) APF530 (sustained-release granisetron) and intravenous (IV) granisetron on placebo-adjusted change from baseline in QT corrected with the Fridericia method (QTcF) over 48 h (ddQTcF)
Publikováno v:
The Journal of Clinical Pharmacology. 27:756-761
The effects of prazosin and beta-blocker monotherapy on serum concentrations of triglycerides, cholesterol, and lipoprotein cholesterol were evaluated in 16 patients with mild to moderate essential hypertension in a single-blind, cross-over, placebo-
Autor:
Albert J. Dietz
Publikováno v:
Postgraduate Medicine. 70:203-208