Zobrazeno 1 - 10
of 306
pro vyhledávání: '"Albert J. Becker"'
Autor:
Daniel S. Galvis-Montes, Karen M. J. van Loo, Ashley J. van Waardenberg, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Transient brain insults including status epilepticus (SE) can initiate a process termed ‘epileptogenesis’ that results in chronic temporal lobe epilepsy. As a consequence, the entire tri-synaptic circuit of the hippocampus is fundamental
Externí odkaz:
https://doaj.org/article/2d824e767dd14c728075aa14d652228a
Autor:
Philipp Müller, Dirk Dietrich, Susanne Schoch, Julika Pitsch, Albert J. Becker, Silvia Cases-Cunillera
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106364- (2024)
Gangliogliomas (GGs) represent the most frequent glioneuronal tumor entity associated with chronic recurrent seizures; rare anaplastic GGs variants retain the glioneuronal character. So far, key mechanisms triggering chronic hyperexcitability in the
Externí odkaz:
https://doaj.org/article/ab464e022fb04863b4ddb1e4bca64b6c
Autor:
Amira Sayed Hanafy, Pia Steinlein, Julika Pitsch, Mariella Hurtado Silva, Natascha Vana, Albert J. Becker, Mark Evan Graham, Susanne Schoch, Alf Lamprecht, Dirk Dietrich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The blood-brain barrier (BBB) tightly and dynamically regulates exchange with the brain. Here, the authors report a brain slice approach to study the native BBB in a highly controlled manner by combining intravascular perfusion and multiphoton micros
Externí odkaz:
https://doaj.org/article/4cb633c9c9004c6bbbdb5c97f9e673c4
Autor:
Andre Dik, Guido Widman, Andreas Schulte‐Mecklenbeck, Juri‐Alexander Witt, Julika Pitsch, Kristin S. Golombeck, Jan Wagner, Marco Gallus, Christine Strippel, Niels Hansen, Constanze Mönig, Saskia Räuber, Heinz Wiendl, Christian E. Elger, Rainer Surges, Sven G. Meuth, Christoph Helmstaedter, Catharina C. Gross, Albert J. Becker, Nico Melzer
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 12, Pp 2289-2301 (2021)
Abstract Objective Direct pathogenic effects of autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GAD65) in autoimmune limbic encephalitis (LE) have been questioned due to its intracellular localization. We therefore hypothesized a
Externí odkaz:
https://doaj.org/article/9d05e3b0b880426b8a6d71870f8730c4
Autor:
Johannes Wach, Motaz Hamed, Tim Lampmann, Ági Güresir, Frederic Carsten Schmeel, Albert J. Becker, Ulrich Herrlinger, Hartmut Vatter, Erdem Güresir
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveMIB-1 index is an important predictor of meningioma progression. However, MIB-1 index is not available in the preoperative tailored medical decision-making process. A preoperative scoring sheet independently estimating MIB-1 indices in spina
Externí odkaz:
https://doaj.org/article/a470dceb5b334c809d53c754fe453cc3
Autor:
Niels Hansen, Guido Widman, Demet Önder, Kerstin Schwing, Pitshaporn Leelaarporn, Indra Prusseit, Randi von Wrede, Rainer Surges, Albert J. Becker, Juri-Alexander Witt, Christian E. Elger, Christoph Helmstaedter
Publikováno v:
Journal of Translational Autoimmunity, Vol 5, Iss , Pp 100167- (2022)
Background: Our goal is to investigate the autoantibodies’ presence and immune cells in the bioprobes of autoimmune encephalitis (AE) patients with distinct phenotypes as a promising target in AE. Methods: We retrospectively analyzed immune cells v
Externí odkaz:
https://doaj.org/article/d33506b91f094685a2bf1f758638c07d
Autor:
Despina Tsortouktzidis, Anna R. Tröscher, Herbert Schulz, Thoralf Opitz, Susanne Schoch, Albert J. Becker, Karen M. J. van Loo
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2022)
Precise genome editing in combination with viral delivery systems provides a valuable tool for neuroscience research. Traditionally, the role of genes in neuronal circuits has been addressed by overexpression or knock-out/knock-down systems. However,
Externí odkaz:
https://doaj.org/article/aaf2e69f713440a4b28de2318c21faa1
Autor:
Attila Rácz, Albert J. Becker, Carlos M. Quesada, Valeri Borger, Hartmut Vatter, Rainer Surges, Christian E. Elger
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Purpose: Focal cortical dysplasias (FCDs) are a frequent cause of drug-resistant focal epilepsies. These lesions are in many cases amenable to epilepsy surgery. We examined 12-month and long-term post-surgical outcomes and its predictors including po
Externí odkaz:
https://doaj.org/article/da2cccfb32c94070948e3d17fe71179b
Autor:
Karen M. J. van Loo, Albert J. Becker
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2020)
Epilepsy is a common neurological disorder characterized by recurrent uncontrolled seizures and has an idiopathic “genetic” etiology or a symptomatic “acquired” component. Genetic studies have revealed that many epilepsy susceptibility genes
Externí odkaz:
https://doaj.org/article/1ac99a0c01b84e04b1f41642d5e2b478
Autor:
Tobias Bauer, Leon Ernst, Bastian David, Albert J. Becker, Jan Wagner, Juri-Alexander Witt, Christoph Helmstaedter, Bernd Weber, Elke Hattingen, Christian E. Elger, Rainer Surges, Theodor Rüber
Publikováno v:
NeuroImage: Clinical, Vol 27, Iss , Pp 102289- (2020)
Limbic encephalitis (LE) is an autoimmune syndrome often associated with temporal lobe epilepsy. Recent research suggests that particular structural changes in LE depend on the type of the associated antibody and occur in both mesiotemporal gray matt
Externí odkaz:
https://doaj.org/article/2d802ec8fb274ea4b289d8aec21a627d