Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Albert J Jin"'
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46107 (2012)
Many fundamental cell processes, such as angiogenesis, neurogenesis and cancer metastasis, are thought to be modulated by extracellular matrix stiffness. Thus, the availability of matrix substrates having well-defined stiffness profiles can be of gre
Externí odkaz:
https://doaj.org/article/017d1ee47fa5467ba975a85c29aea4e1
Autor:
Nicholas J. MacDonald, Kavita Singh, Karine Reiter, Vu Nguyen, Richard Shimp, Apostolos G. Gittis, Beth Chen, Martin Burkhardt, Baoshan Zhang, Zhixiong Wang, Raul Herrera, Mackenzie Moler, Duck-Yeon Lee, Sachy Orr-Gonzalez, Jessica Herrod, Lynn E. Lambert, Kelly M. Rausch, Olga Muratova, David S. Jones, Yimin Wu, Albert J. Jin, David N. Garboczi, Patrick E. Duffy, David L. Narum
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Development of a malaria vaccine that blocks transmission of different parasite stages to humans and mosquitoes is considered critical for elimination efforts. A vaccine using Pfs25, a protein on the surface of zygotes and ookinetes, is unde
Externí odkaz:
https://doaj.org/article/744dd43cb85546b1a8f8ee76086ef8c5
Publikováno v:
Mater Horiz
Photonic theranostics (PTs) generally contain optical agents for the optical sensing of biomolecules and therapeutic components for converting light into heat or chemical energy. Semiconducting polymer nanoparticles (SPNs) as advanced PTs possessing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5e56381b39969cd20b5a09a5419b18
https://europepmc.org/articles/PMC7990392/
https://europepmc.org/articles/PMC7990392/
Autor:
Bryant C. Yung, Zhen Yang, Xiaoyuan Chen, Zhengwei Mao, Sheng Wang, Orit Jacobson, Bin Hua, Changyou Gao, Li Shao, Fuwu Zhang, Xiaoying Tang, Yijing Liu, Feihe Huang, Jie Yang, Albert J. Jin, Xiao Fu, Guocan Yu, Quli Fan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
The development of smart theranostic systems with favourable biocompatibility, high loading efficiency, excellent circulation stability, potent anti-tumour activity, and multimodal diagnostic functionalities is of importance for future clinical appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::022d04c7b02a10560a163d660331d005
https://doaj.org/article/55dabb77adbd469d974b5bb85b4ec0e7
https://doaj.org/article/55dabb77adbd469d974b5bb85b4ec0e7
Autor:
Rui Su, Ling-Gang Wu, Oleg Shupliakov, Sathish Thiyagarajan, Xiaoli Guo, Lisi Wei, Zachary A. McDargh, Ben O'Shaughnessy, Gianvito Arpino, Lihao Ge, Wonchul Shin, Albert J. Jin
Publikováno v:
Cell reports
Cell Reports, Vol 30, Iss 2, Pp 421-431.e7 (2020)
Cell Reports, Vol 30, Iss 2, Pp 421-431.e7 (2020)
SUMMARY For decades, two fusion modes were thought to control hormone and transmitter release essential to life; one facilitates release via fusion pore dilation and flattening (full collapse), and the other limits release by closing a narrow fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89b27b8addd2b73a4baeaaefeb89508
https://pubmed.ncbi.nlm.nih.gov/31940486
https://pubmed.ncbi.nlm.nih.gov/31940486
Autor:
Wei Huang, Deqiang Gan, Albert J. Jin, Xiaoming Hu, Zhen Yang, Aifang Wu, Haiyong Ao, Zejing Chen, Quli Fan
Publikováno v:
Small. 17:2007566
Organic theranostic nanomedicine has precision multimodel imaging capability and concurrent therapeutics under noninvasive imaging guidance. However, the rational design of desirable multifunctional organic theranostics for cancer remains challenging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75a9ba71ead887b9c1fa4ecea76ef1c
https://doi.org/10.1002/smll.202007566
https://doi.org/10.1002/smll.202007566
Autor:
Suping Jin, Hsien-Shun Liao, Rui J Sousa, Albert J. Jin, Jorge Cuéllar, José M. Valpuesta, Eileen M. Lafer
Publikováno v:
Nature structural & molecular biology
Hsp70s use ATP hydrolysis to disrupt protein-protein associations and to move macromolecules. One example is the Hsc70- mediated disassembly of the clathrin coats that form on vesicles during endocytosis. Here, we exploited the exceptional features o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63715f3c20c3e9e819fc97489c382882
https://doi.org/10.1038/nsmb.3272
https://doi.org/10.1038/nsmb.3272
Autor:
Rui Su, Albert J. Jin, Wonchul Shin, Zachary A. McDargh, Lisi Wei, Sathish Thiyagarajan, Xiaoli Guo, Oleg Shupliakov, Ling-Gang Wu, Ben O'Shaughnessy, Lihao Ge, Gianvito Arpino
Publikováno v:
Biophysical Journal. 118:399a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93a485762d13ecc6b0104d015a66fc2d
https://doi.org/10.1016/j.bpj.2019.11.2266
https://doi.org/10.1016/j.bpj.2019.11.2266
Publikováno v:
J Biomech Eng
Atomic force microscopy (AFM) has been used to measure cellular stiffness at different osmolarities to investigate the effect of osmotic pressure on cells. However, substantial direct evidence is essential to clarify the phenomena derived from the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea366c380f954e965895d35bd5b4b84e
https://doi.org/10.1115/1.4039378
https://doi.org/10.1115/1.4039378
Autor:
Gang Niu, Hari Shroff, Albert J. Jin, Kai Chen, Xiaoyuan Chen, Siyuan Cheng, Huimin Zhang, Ying Ma, Harshad D. Vishwasrao, Bryant C. Yung, Yi Liu, Nan Lu, Zhe Wang, Orit Jacobson, Xiao Fu, Lixin Lang, Robert A. Seder, Dennis M. Klinman, Rui Tian, Geoffrey M. Lynn, Fuwu Zhang, Qianqian Ni, Ido D. Weiss, Guizhi Zhu, Zhantong Wang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
Subunit vaccines have been investigated in over 1000 clinical trials of cancer immunotherapy, but have shown limited efficacy. Nanovaccines may improve efficacy but have rarely been clinically translated. By conjugating molecular vaccines with Evans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe63d73c04c2ccceb9eb5bf63151c71f
https://doi.org/10.1038/s41467-017-02191-y
https://doi.org/10.1038/s41467-017-02191-y