Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Albert J, Dietz"'
Autor:
Albert J. Dietz, Robert Townsend, Christopher Lademacher, Donna Kowalski, Amit Desai, Helene Pearlman, Shahzad Akhtar, Takao Yamazaki
Publikováno v:
Clinical Pharmacology in Drug Development. 6:86-92
This phase 1 trial evaluated pharmacokinetic and pharmacodynamic interactions between the novel triazole antifungal agent isavuconazole and warfarin in healthy adults. Multiple doses of isavuconazole were administered as the oral prodrug, isavuconazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07608147e8c72262110e6e3ea583c7a0
https://doi.org/10.1002/cpdd.283
https://doi.org/10.1002/cpdd.283
Autor:
Helene Pearlman, Amit Desai, Kenneth C. Lasseter, Christopher Lademacher, Christine Hale, Donna Kowalski, Shahzad Akhtar, Anne Schmitt-Hoffmann, Albert J. Dietz, Robert Townsend, Diane Rammelsberg, Takao Yamazaki
Publikováno v:
Clinical Pharmacology in Drug Development. 6:44-53
This report describes the phase 1 trials that evaluated the metabolism of the novel triazole antifungal isavuconazole by cytochrome P450 3A4 (CYP3A4) and isavuconazole's effects on CYP3A4-mediated metabolism in healthy adults. Coadministration of ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c1f5aa7377157f0f9e2ca74eb611ea4
https://doi.org/10.1002/cpdd.285
https://doi.org/10.1002/cpdd.285
Publikováno v:
Clinical Pharmacology in Drug Development. 3:25-33
Albaconazole is a triazole antifungal agent discovered at Palau Pharma SA (Barcelona, Spain) and currently being developed for the treatment of fungal infections of the nails. This randomized, double-blind, placebo-controlled, phase 1 study evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c15c1d56db3fd1de0032013901d3a1cb
https://doi.org/10.1002/cpdd.72
https://doi.org/10.1002/cpdd.72
Autor:
Amit, Desai, Takao, Yamazaki, Albert J, Dietz, Donna, Kowalski, Christopher, Lademacher, Helene, Pearlman, Shahzad, Akhtar, Robert, Townsend
Publikováno v:
Clinical Pharmacology in Drug Development
This phase 1 trial evaluated pharmacokinetic and pharmacodynamic interactions between the novel triazole antifungal agent isavuconazole and warfarin in healthy adults. Multiple doses of isavuconazole were administered as the oral prodrug, isavuconazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::737ce64ee0543c695dc38e093f90e04b
https://pubmed.ncbi.nlm.nih.gov/27278712
https://pubmed.ncbi.nlm.nih.gov/27278712
Publikováno v:
Cancer Management and Research
Jay W Mason,1 Thomas E Moon,2 Erin O’Boyle,3 Albert Dietz41Department of Medicine, University of Utah, Salt Lake City, UT, 2Tarizona eHealth Services, Inc., San Carlos, CA, 3AP Pharma, Redwood City, CA, 4Spaulding Clinical Research, West Bend, WI,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ed85ed03740f6977d6dce256fddc8b
https://www.dovepress.com/a-randomized-placebo-controlled-four-period-crossover-definitive-qt-st-peer-reviewed-article-CMAR
https://www.dovepress.com/a-randomized-placebo-controlled-four-period-crossover-definitive-qt-st-peer-reviewed-article-CMAR
Autor:
Donna Dorozinsky, Susana R. K. de Dennis, Mariana Kiefer-Johnson, Albert J. Dietz, Gary L. Steinman, William L. Hirschhorn, Howard Uderman
Publikováno v:
Drug Information Journal. 31:751-757
Clinical Pharmacology Units (CPUs) are a special class of clinical research units for investigating the pharmacokinetic, pharmacodynamic, and toxicologic properties of drugs in man. The Association of Clinical Pharmacology Units (ACPU) is a national
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d48676d03fe971f73887a0cdd986af87
https://doi.org/10.1177/009286159703100316
https://doi.org/10.1177/009286159703100316
Publikováno v:
Clinical pharmacology in drug development. 3(1)
Albaconazole is a triazole antifungal agent discovered at Palau Pharma SA (Barcelona, Spain) and currently being developed for the treatment of fungal infections of the nails. This randomized, double-blind, placebo-controlled, phase 1 study evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a60bdf2d6b3b3db69fea0afe6bf0a1b
https://pubmed.ncbi.nlm.nih.gov/27128227
https://pubmed.ncbi.nlm.nih.gov/27128227
Publikováno v:
Journal of Clinical Oncology. 31:e20539-e20539
e20539 Background: This study evaluated effects of subcutaneous (SC) APF530 (sustained-release granisetron) and intravenous (IV) granisetron on placebo-adjusted change from baseline in QT corrected with the Fridericia method (QTcF) over 48 h (ddQTcF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4eae2e50ebacd5c6366fcfc0d28aa6a
https://doi.org/10.1200/jco.2013.31.15_suppl.e20539
https://doi.org/10.1200/jco.2013.31.15_suppl.e20539
Publikováno v:
The Journal of Clinical Pharmacology. 27:756-761
The effects of prazosin and beta-blocker monotherapy on serum concentrations of triglycerides, cholesterol, and lipoprotein cholesterol were evaluated in 16 patients with mild to moderate essential hypertension in a single-blind, cross-over, placebo-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d9826c5b46958c4ecd2c8ca3e19209
https://doi.org/10.1002/j.1552-4604.1987.tb02992.x
https://doi.org/10.1002/j.1552-4604.1987.tb02992.x
Autor:
Albert J. Dietz
Publikováno v:
Postgraduate Medicine. 70:203-208
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1fa67d6dde56e61804cfb91a255c32
https://doi.org/10.1080/00325481.1981.11715865
https://doi.org/10.1080/00325481.1981.11715865