Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Albert Hee Lum Chow"'
Autor:
Jingwen Weng, Si Nga Wong, Shing Fung Chow, Ka Yee Wan, Philip Chi Lip Kwok, Albert Hee Lum Chow
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 149:238-247
While nanoparticulate drugs for deep lung delivery hold promise for particular disease treatments, their size-related physical instability and tendency of being exhaled during breathing remain major challenges to their inhaled formulation development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c47e98c062fa3c362321748da4723e
https://doi.org/10.1016/j.ejpb.2020.02.010
https://doi.org/10.1016/j.ejpb.2020.02.010
Autor:
Albert Hee Lum Chow, Wai Yip Thomas Lee, Shenye Hu, Xiaoyan Xu, Wai Wing Ng, Si Nga Wong, Shing Fung Chow, Ka Lun Lai, Changquan Calvin Sun
Publikováno v:
Crystal Growth & Design. 18:5534-5546
Recent advances in crystal engineering by cocrystallization have offered a promising approach for tackling undesirable physicochemical properties of drug substances. In this study, various structur...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2af8dc59a88fb5958d3d38868ee8261b
https://doi.org/10.1021/acs.cgd.8b00849
https://doi.org/10.1021/acs.cgd.8b00849
Publikováno v:
International Journal of Pharmaceutics. 542:221-231
Flash nanoprecipitation (FNP) is a controlled antisolvent precipitation process that has proven effective for consistent production of drug nanoparticles with a defined mean particle size and narrow particle size distribution. However, physical insta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f183cb4c476e354d4448a538648d22
https://doi.org/10.1016/j.ijpharm.2018.03.006
https://doi.org/10.1016/j.ijpharm.2018.03.006
Publikováno v:
Molecular pharmaceutics. 16(1)
While flash nanoprecipitation (FNP) has proven to be an extremely rapid and highly efficient nanoparticle fabrication process for hydrophobic drugs, physical instability associated with nonequilibrium molecular orientation of amphiphilic stabilizers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b39c9e7244d38f0c98b3a8f09193db
https://pubmed.ncbi.nlm.nih.gov/30525643
https://pubmed.ncbi.nlm.nih.gov/30525643
Publikováno v:
International Journal of Pharmaceutics. 494:479-489
The present study was aimed at tailoring the particle size of ursolic acid (UA) nanosuspension for improved anticancer activity. UA nanosuspensions were prepared by antisolvent precipitation using a four-stream multi-inlet vortex mixer (MIVM) under d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11037e7f294e7cfcd3b3e9f3bcedcaef
https://doi.org/10.1016/j.ijpharm.2015.08.052
https://doi.org/10.1016/j.ijpharm.2015.08.052
Autor:
Larry Baum, Albert Hee Lum Chow, Shing Fung Chow, Changquan Calvin Sun, Kwok Kin Cheng, Ka Wai Wong, Ka Yee Wan
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 94:436-449
The influence of critical operating parameters on the Flash Nanoprecipitation (FNP) and resulting material properties of curcumin (CUR) nanoparticles has been evaluated using a confined impinging jets-with-dilution mixer (CIJ-D-M). It has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab22c20bf4d2e1b9eb691d43bea35f05
https://doi.org/10.1016/j.ejpb.2015.06.022
https://doi.org/10.1016/j.ejpb.2015.06.022
Autor:
Karthik Nagapudi, Albert Hee Lum Chow, Limin Shi, Shing Fung Chow, Wai Wing Ng, Kari Hoi Yan Leung, Changquan Calvin Sun
Publikováno v:
Crystal Growth & Design. 14:5079-5089
The existence of a cocrystal between curcumin (CUR) and phloroglucinol (PHL) was suspected but could not be demonstrated in a recent systematic effort to synthesize novel curcumin cocrystals. We hypothesize that the elusive CUR–PHL cocrystal is a k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7ed0cf819ca52e42c251602c8cbce92
https://doi.org/10.1021/cg5007007
https://doi.org/10.1021/cg5007007
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 88(2)
The relative performance of two specially designed mixers for nanoparticle production, namely, two-stream confined impinging jets with dilution mixer (CIJ-D-M) and four-stream multi-inlet vortex mixer (MIVM), was evaluated using the model compound, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7244f673398063a82a80d55806665b35
https://pubmed.ncbi.nlm.nih.gov/25016977
https://pubmed.ncbi.nlm.nih.gov/25016977
Autor:
Kwok Kin Cheng, Albert Hee Lum Chow, Larry Baum, Chin Fung Yeung, Shuk Wai Ho, Shing Fung Chow
The therapeutic effects of curcumin in treating Alzheimer’s disease (AD) depend on the ability to penetrate the blood–brain barrier. The latest nanoparticle technology can help to improve the bioavailability of curcumin, which is affected by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d7f3b3b469ff140a705e742d5b3d0f
https://europepmc.org/articles/PMC3675736/
https://europepmc.org/articles/PMC3675736/
Publikováno v:
Pharmaceutical research. 29(7)
To be fully exploitable in both formulation and manufacturing, a drug cocrystal needs to demonstrate simultaneous improvement of multiple key pharmaceutical properties over the pure drug crystal. The present work was aimed at investigating such feasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4dc71fc2aac46c6c4cf2be7537b54a
https://pubmed.ncbi.nlm.nih.gov/22359146
https://pubmed.ncbi.nlm.nih.gov/22359146