Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Albert H. L. Chow"'
Autor:
Henry H. Y. Tong, Albert H. L. Chow
Publikováno v:
KONA Powder and Particle Journal, Vol 24, Iss 0, Pp 27-40 (2014)
Dry powder inhalation (DPI) is an important means of pulmonary drug delivery for both local and systemic actions. Since drugs of different solid-state chemistry can influence a wide range of physical, chemical and biological properties, control of th
Externí odkaz:
https://doaj.org/article/d013213151284d5ea48dc88d277d7772
Publikováno v:
KONA Powder and Particle Journal, Vol 20, Iss 0, Pp 178-187 (2014)
Comparative analysis between salmeterol xinafoate (SX) powders was carried out to define quantitatively the solid-state and surface particle properties relevant to formulation of these materials into dry powder respiratory drug delivery systems. SX p
Externí odkaz:
https://doaj.org/article/ec0d5acce1c44456a601d3be314b2e93
Autor:
Jingwen Weng, Albert H. L. Chow, Shing Fung Chow, Li Yin Chau, Ka Wai Wong, Ho Wan Chan, Xin-ran Zhang
Publikováno v:
International journal of pharmaceutics. 598
Ibuprofen (IBP), a common non-steroidal anti-inflammatory drug (NSAID) with a log P of 3.51, has been shown to possess potential benefit in the treatment of Alzheimer’s disease. However, the bioavailability of IBP to the brain is poor, which can be
Publikováno v:
CrystEngComm. 20:5486-5489
Commercial baicalein (α form) exhibits deficient tabletability. Cocrystals of baicalein with nicotinamide, caffeine, and isoniazid were all shown to display excellent tabletability, despite the three coformers having high, medium, and poor tabletabi
Publikováno v:
Crystal Growth & Design. 17:3433-3442
The crystal structure of itraconazole (ITZ) Form II has been determined by single-crystal X-ray diffraction, and the effects of crystal structure and two polymer excipients, Kollidone VA64 (PVPVA64) and hydroxypropylmethyl cellulose acetate succinate
Autor:
Xiao Qing Miao, Albert H. L. Chow, Yong-Hong Liao, Chao Bi, Ying Zheng, Ru Yan, Sing Fung Chow, Wenjin Wu
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 13:943-953
This study aimed to investigate the particle size effect on bioactivity, cellular internalization and bioavailability of curcumin (CUR) nanosuspension (CUR-NS). CUR-NSs of different particle sizes were prepared by two different anti-solvent precipita
Publikováno v:
Crystal Growth & Design. 16:3791-3801
The impacts of the nucleation site and temperature on the melt crystallization of itraconazole (ITZ) were investigated. ITZ recrystallized from melt into three distinct spherulite zones between two glass coverslips, as observed under a polarized ligh
Publikováno v:
International journal of pharmaceutics. 555
Two pharmaceutical polymers with high glass transition temperatures (Tg > 100 °C), polyvinylpyrrolidone-vinyl acetate copolymer (PVPVA) and hydroxypropyl methylcellulose acetate succinate (HPMCAS), have been assessed for their impact on the storage
Publikováno v:
KONA Powder and Particle Journal, Vol 20, Iss 0, Pp 178-187 (2014)
Comparative analysis between salmeterol xinafoate (SX) powders was carried out to define quantitatively the solid-state and surface particle properties relevant to formulation of these materials into dry powder respiratory drug delivery systems. SX p
Publikováno v:
Current Pharmaceutical Design. 20:303-324
Solid state manipulation by amorphous solid dispersion has been the subject of intensive research for decades due to their excellent potential for dissolution and bioavailability enhancement. The present review aims to highlight the latest advancemen