Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Albert H C, Wong"'
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that has caused a global pandemic Coronavirus Disease 2019 (COVID-19). Currently, there are no effective treatments specifically for COVID-19 infection. The
Externí odkaz:
https://doaj.org/article/01bd85fe54a7474ea276fd24032d0e78
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Major depressive disorder (MDD) is associated with significant morbidity and mortality. Most antidepressant medications target the serotonin and norepinephrine transporters, but a significant minority of patients do not respond to treatment
Externí odkaz:
https://doaj.org/article/1fe716ab1f0049dd8a20b8d39f2a7f62
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-8 (2020)
Abstract The Disrupted in schizophrenia 1 (DISC1) gene encodes a scaffolding protein that is involved in many neural functions such as neurogenesis, neural differentiation, embryonic neuron migration and neurotransmitter signalling. DISC1 was origina
Externí odkaz:
https://doaj.org/article/5331868eb95c4f6cafbeafaa15635d10
Autor:
Helena K. Kim, Andre F. Carvalho, David Gratzer, Albert H. C. Wong, Shayla Gutzin, M. Ishrat Husain, Benoit H. Mulsant, Vicky Stergiopoulos, Zafiris J. Daskalakis
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The World Health Organization characterized COVID-19 (coronavirus disease 2019) as a pandemic on March 11, 2020 (WHO). Within a couple of days, all Canadian provinces announced the implementation of social distancing measures. We evaluated the immedi
Externí odkaz:
https://doaj.org/article/f09da0bc10e141a687e806ca86be7105
Autor:
Wei Wang, Paul Kurdyak, Claire de Oliveira, Vicky Stergiopoulos, Joanna Henderson, Aristotle N Voineskos, Kelly K Anderson, Nicole Kozloff, George Foussias, Augustina Ampofo, Sarah Bromley, Lillian Duda, Juveria Zaheer, Alexia Polillo, Albert H C Wong, Jessica D'Arcey, Sean Kidd
Publikováno v:
BMJ Open, Vol 10, Iss 12 (2020)
Introduction While nearly half of all new psychotic disorders are diagnosed in the emergency department (ED), most young people who present to the ED with psychosis do not receive timely follow-up with a psychiatrist, and even fewer with evidence-bas
Externí odkaz:
https://doaj.org/article/b5285cff47404b49b9dfc9b85d950ee4
Autor:
Gabriel Oh, Karolis Koncevičius, Sasha Ebrahimi, Matthew Carlucci, Daniel Erik Groot, Akhil Nair, Aiping Zhang, Algimantas Kriščiūnas, Edward S. Oh, Viviane Labrie, Albert H. C. Wong, Juozas Gordevičius, Peixin Jia, Miki Susic, Art Petronis
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Maintenance of physiological circadian rhythm plays a crucial role in human health. Numerous studies have shown that disruption of circadian rhythm may increase risk for malignant, psychiatric, metabolic, and other diseases. Resul
Externí odkaz:
https://doaj.org/article/0bb0cf17ddd74d83b454d4798856c92c
Autor:
Jing Liu, Lili Tong, Shuangshuang Song, Yue Niu, Jun Li, Xiu Wu, Jie Zhang, Clement C. Zai, Fang Luo, Jian Wu, Haiyin Li, Albert H. C. Wong, Ruopeng Sun, Fang Liu, Baomin Li
Publikováno v:
Molecular Brain, Vol 11, Iss 1, Pp 1-18 (2018)
Abstract Pediatric refractory epilepsy is a broad phenotypic spectrum with great genetic heterogeneity. Next-generation sequencing (NGS) combined with Sanger sequencing could help to understand the genetic diversity and underlying disease mechanisms
Externí odkaz:
https://doaj.org/article/d4bb2f74b66d46b5a634f25515ede3f2
Autor:
Anlong Jiang, Le Wang, Justin Y. D. Lu, Amy Freeman, Charlie Campbell, Ping Su, Albert H. C. Wong, Fang Liu
Publikováno v:
Brain Sciences, Vol 11, Iss 11, p 1398 (2021)
Fragile X syndrome (FXS) is an X-chromosome-linked dominant genetic disorder that causes a variable degree of cognitive dysfunction and developmental disability. Current treatment is symptomatic and no existing medications target the specific cause o
Externí odkaz:
https://doaj.org/article/4d31ac84f8ca48baabd3a110d5c4cedf
Autor:
Yi Yang, Rupali Vyawahare, Melissa Lewis-Bakker, Hance A. Clarke, Albert H. C. Wong, Lakshmi P. Kotra
Publikováno v:
Molecules, Vol 25, Iss 15, p 3466 (2020)
Cannabis is widely used as a therapeutic drug, especially by patients suffering from psychiatric and neurodegenerative diseases. However, the complex interplay between phytocannabinoids and their targets in the human receptome remains largely a myste
Externí odkaz:
https://doaj.org/article/6bf142a4cca849bda7950547087045ea
Autor:
Ping Su, Shuxin Yan, Jian Yang, Junchao Tong, James Samsom, Fan You, Yun Li, Qiuyue Chen, Anlong Jiang, Dongxu Zhai, Jiahao Chen, Zuoli Sun, Jingjing Zhou, Min Liu, Frank J. S. Lee, Zhi-Qing David Xu, Xin Wang, Neil Vasdev, Albert H. C. Wong, Fang Liu
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
Serum amyloid P component (SAP) is a universal constituent of human amyloid deposits including those in Alzheimer's disease. SAP has been observed to be elevated in patients with depression, and higher SAP levels are associated with better response t