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pro vyhledávání: '"Albert H, Chen"'
Autor:
Kumiko, Nagashima, Stuart D, Shumway, Sriram, Sathyanarayanan, Albert H, Chen, Brian, Dolinski, Youyuan, Xu, Heike, Keilhack, Thi, Nguyen, Maciej, Wiznerowicz, Lixia, Li, Bart A, Lutterbach, An, Chi, Cloud, Paweletz, Timothy, Allison, Youwei, Yan, Sanjeev K, Munshi, Anke, Klippel, Manfred, Kraus, Ekaterina V, Bobkova, Sujal, Deshmukh, Zangwei, Xu, Uwe, Mueller, Alexander A, Szewczak, Bo-Sheng, Pan, Victoria, Richon, Roy, Pollock, Peter, Blume-Jensen, Alan, Northrup, Jannik N, Andersen
Phosphoinositide-dependent kinase 1 (PDK1) is a critical activator of multiple prosurvival and oncogenic protein kinases and has garnered considerable interest as an oncology drug target. Despite progress characterizing PDK1 as a therapeutic target,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffa77558274950b04bf7d0ff36cc73f0
http://hdl.handle.net/10722/156005
http://hdl.handle.net/10722/156005
Autor:
Gerald R. Crabtree, Daniel Hsieh-Hsin Li, Paul J. Utz, Monte M. Winslow, Albert H. Chen, Jane R. Parnes, Thai M. Cao, Corrine R. Davis, Elizabeth D. Mellins
Publikováno v:
Arthritis and rheumatism. 58(10)
B cell self tolerance is maintained by several mechanisms, including deletion, receptor editing, and anergy (1–4). Mechanisms of peripheral tolerance are thought to be important, because a considerable proportion of self-reactive B cells escape cen