Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Albert Geishauser"'
Autor:
Ellen Brenner, Barbara F. Schörg, Fatima Ahmetlić, Thomas Wieder, Franz Joachim Hilke, Nadine Simon, Christopher Schroeder, German Demidov, Tanja Riedel, Birgit Fehrenbacher, Martin Schaller, Andrea Forschner, Thomas Eigentler, Heike Niessner, Tobias Sinnberg, Katharina S. Böhm, Nadine Hömberg, Heidi Braumüller, Daniel Dauch, Stefan Zwirner, Lars Zender, Dominik Sonanini, Albert Geishauser, Jürgen Bauer, Martin Eichner, Katja J. Jarick, Andreas Beilhack, Saskia Biskup, Dennis Döcker, Dirk Schadendorf, Leticia Quintanilla-Martinez, Bernd J. Pichler, Manfred Kneilling, Ralph Mocikat, Martin Röcken
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
The growth of cancer cells can be stably arrested by cytokine-induced senescence. Here, the authors show that cancers with defects in senescence-inducing cell cycle regulator pathways are resistant to immune checkpoint blockade.
Externí odkaz:
https://doaj.org/article/ffeefb0c18174583b0c353a1c64a24f9
Publikováno v:
Translational Oncology, Vol 14, Iss 9, Pp 101170- (2021)
In malignant disease, CD4+Foxp3+ regulatory T cells (Tregs) hamper antitumor immune responses and may provide a target for immunotherapy. Although immune checkpoint blockade (ICB) has become an established therapy for several cancer entities includin
Externí odkaz:
https://doaj.org/article/c49efe5c27f249e588bbfc6e907c1d97
Autor:
Ralph Mocikat, Martin Röcken, Stefan Stevanović, Tim Sparwasser, Albert Geishauser, Nico Trautwein, Vera Bauer, Nadine Hömberg, Tanja Riedel, Fatima Ahmetlić
Foxp3+ regulatory T cells (Tregs) sustain immune homeostasis and may contribute to immune escape in malignant disease. As a prerequisite for developing immunologic approaches in cancer therapy, it is necessary to understand the ontogeny and the antig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1b0eb7ba2c40a84b33e526999aa2d5f
https://doi.org/10.1158/2326-6066.c.6549085.v1
https://doi.org/10.1158/2326-6066.c.6549085.v1
Autor:
Ralph Mocikat, Martin Röcken, Stefan Stevanović, Tim Sparwasser, Albert Geishauser, Nico Trautwein, Vera Bauer, Nadine Hömberg, Tanja Riedel, Fatima Ahmetlić
Supplementary figures and table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692c499f3dc6034769b2b4c05229f968
https://doi.org/10.1158/2326-6066.22539412
https://doi.org/10.1158/2326-6066.22539412
Publikováno v:
Transl. Oncol. 14:101170 (2021)
Translational Oncology
Translational Oncology, Vol 14, Iss 9, Pp 101170-(2021)
Translational Oncology
Translational Oncology, Vol 14, Iss 9, Pp 101170-(2021)
Highlights • During lymphoma growth, Tregs evolve an increasingly suppressive phenotype. • Lymphoma-infiltrating Tregs show an enhanced immunosuppressive function. • Cell contacts and IL-10 are required for Treg-mediated immunosuppression. •
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9062cf3534fdd9f658b074d4bac406ca
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62407
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62407
Autor:
Albert Geishauser, Andreas Beilhack, Tanja Riedel, Bernd J. Pichler, Jürgen Bauer, Nadine Simon, Fatima Ahmetlić, Heidi Braumüller, Saskia Biskup, Nadine Hömberg, Martin Schaller, Dennis Döcker, Christopher Schroeder, Lars Zender, Andrea Forschner, Franz J. Hilke, Manfred Kneilling, Thomas Eigentler, Katharina Böhm, Ellen Brenner, Dirk Schadendorf, Birgit Fehrenbacher, Stefan Zwirner, B.F. Schörg, German Demidov, Martin Eichner, Thomas Wieder, Heike Niessner, Leticia Quintanilla-Martinez, Tobias Sinnberg, Ralph Mocikat, Martin Röcken, Dominik Sonanini, Daniel Dauch, Katja J. Jarick
Publikováno v:
Nat. Commun. 11:1335 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Immune checkpoint blockade (ICB)-based or natural cancer immune responses largely eliminate tumours. Yet, they require additional mechanisms to arrest those cancer cells that are not rejected. Cytokine-induced senescence (CIS) can stably arrest cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a6fc7f2a9ae75483c50433edab7d47
https://doi.org/10.1038/s41467-020-14987-6
https://doi.org/10.1038/s41467-020-14987-6
Autor:
Christoph D. Brenner, Ralph Mocikat, Johann Pötzl, Martin Röcken, Albert Geishauser, David Roser, Nadine Hömberg, Michael Weigand, Lorenz Bankel
Publikováno v:
International Journal of Cancer. 140:2125-2133
Like other immune cells, natural killer (NK) cells show impaired effector functions in the microenvironment of tumors, but little is known on the underlying mechanisms. Since lactate acidosis, a hallmark of malignant tissue, was shown to contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b3acd0bbf4c8c71359e833d1058999d
https://doi.org/10.1002/ijc.30646
https://doi.org/10.1002/ijc.30646
Autor:
J. Wei, Sabine Blum, Gergely Jarmy, Antonis K. Hatzopoulos, Mathias Lamparter, Georgios A. Vlastos, Gordon Chan, Marcus M. Unger, Albert Geishauser, Dirk Rattat, Klaus-Michael Debatin, Klaus-Dieter Fischer, Christian Beltinger
Publikováno v:
Cancer Cell 5, 477-488 (2004)
We show that mouse embryonic endothelial progenitor cells (eEPCs) home preferentially to hypoxic lung metastases when administered intravenously. This specificity is inversely related to the degree of perfusion and vascular density in the metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f8e6be7e17bbbb6d5f480fd04baf22
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=3303
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=3303