Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Albert Feghaly"'
Autor:
Marie-Eve Bordeleau, Éric Audemard, Arnaud Métois, Louis Theret, Véronique Lisi, Azer Farah, Jean-François Spinella, Jalila Chagraoui, Ossama Moujaber, Léo Aubert, Banafsheh Khakipoor, Laure Mallinger, Isabel Boivin, Nadine Mayotte, Azadeh Hajmirza, Éric Bonneil, François Béliveau, Sybille Pfammatter, Albert Feghaly, Geneviève Boucher, Patrick Gendron, Pierre Thibault, Frédéric Barabé, Sébastien Lemieux, Guillaume Richard-Carpentier, Josée Hébert, Vincent-Philippe Lavallée, Philippe P. Roux, Guy Sauvageau
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114260- (2024)
Summary: Immunotherapy remains underexploited in acute myeloid leukemia (AML) compared to other hematological malignancies. Currently, gemtuzumab ozogamicin is the only therapeutic antibody approved for this disease. Here, to identify potential targe
Externí odkaz:
https://doaj.org/article/8cf475f1511748f0b536ab3c7b29e97a
Publikováno v:
PLoS Biology, Vol 20, Iss 12 (2022)
Recent theoretical models suggest that deciding about actions and executing them are not implemented by completely distinct neural mechanisms but are instead two modes of an integrated dynamical system. Here, we investigate this proposal by examining
Externí odkaz:
https://doaj.org/article/7cb1aa2640da4edcb57893f936903f37
Autor:
Tariq Daouda, Maude Dumont-Lagacé, Albert Feghaly, Yahya Benslimane, Rébecca Panes, Mathieu Courcelles, Mohamed Benhammadi, Lea Harrington, Pierre Thibault, François Major, Yoshua Bengio, Étienne Gagnon, Sébastien Lemieux, Claude Perreault
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 10 (2021)
MHC-I associated peptides (MAPs) play a central role in the elimination of virus-infected and neoplastic cells by CD8 T cells. However, accurately predicting the MAP repertoire remains difficult, because only a fraction of the transcriptome generates
Externí odkaz:
https://doaj.org/article/cbd385c9465f4eb1bec7127d68136b08
Autor:
Maude Dumont-Lagacé, Albert Feghaly, Marie-Christine Meunier, Marcie Finney, Wouter Van't Hof, Emeline Masson Frenet, Guy Sauvageau, Sandra Cohen
Publikováno v:
Transplantation and cellular therapy. 28(7)
Cord blood (CB) stem cell transplantation offers a greater tolerance to HLA mismatches compared to adult-derived stem cell transplants (i.e., bone marrow or peripheral blood stem cells). Indeed, 4/6 or 5/8 HLA-matched CB transplantations are regularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c414511a01511a4fba8c32f55f6d1f61
https://pubmed.ncbi.nlm.nih.gov/35311667
https://pubmed.ncbi.nlm.nih.gov/35311667
Autor:
Maude Dumont-Lagacé, Albert Feghaly, Gabrielle Thauvette, Marie-Christine Meunier, William Lemieux, Diane Fournier, Lucie Richard, Sébastien Lemieux, Guy Sauvageau, Sandra Cohen
Publikováno v:
Stem Cells Translational Medicine. 11:S30-S30
Introduction Cord blood (CB) banks have had to rely on large inventories of CB units to try to serve the largest possible proportion of the population, all the while prioritizing collection of non-Caucasian ethnic groups. However, due to the high lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b408c95c727362b24084f05952aba501
https://doi.org/10.1093/stcltm/szac057.025
https://doi.org/10.1093/stcltm/szac057.025
SummaryAmong various vaccination strategies, peptide-based vaccines appear as excellent candidates because they are cheap to produce, are highly stable and harbor low toxicity. However, predicting which MHC-I Associated Peptide (MAP) will ultimately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f992fbcbeaa097152629e099592c2e50
https://doi.org/10.1101/2021.02.04.429819
https://doi.org/10.1101/2021.02.04.429819
Several theoretical models suggest that deciding about actions and executing them are not completely distinct neural mechanisms but instead two modes of an integrated dynamical system. Here, we investigate this proposal by examining how neural activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df12c580db3066a84784c73563330425
https://doi.org/10.1101/2020.10.22.350280
https://doi.org/10.1101/2020.10.22.350280
Autor:
Albert Feghaly, Catherine Thériault, Grégory Ehx, Josée Hébert, Sébastien Lemieux, Eric Bonneil, Luca Vago, Guy Sauvageau, Jean-Philippe Laverdure, Pierre Thibault, Chantal Durette, Caroline Rulleau, Joel Lanoix, Jean-David Larouche, Marie-Pierre Hardy, Krystel Vincent, Anca Apavaloaei, Leslie Hesnard, Céline M. Laumont, Jean-Sébastien Delisle, Claude Perreault, Nandita Noronha
Publikováno v:
Immunity. 54(4)
Summary Acute myeloid leukemia (AML) has not benefited from innovative immunotherapies, mainly because of the lack of actionable immune targets. Using an original proteogenomic approach, we analyzed the major histocompatibility complex class I (MHC c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea5da67884e96cfb20df5a75499300f
https://pubmed.ncbi.nlm.nih.gov/33852826
https://pubmed.ncbi.nlm.nih.gov/33852826
Autor:
Mariana Acevedo, Lian Mignacca, Yan Yifei, François Major, Gerardo Ferbeyre, Julie Robitaille, Roqaya Imane, Philippe Desjardins, Etienne Gagnon, Nicolas Scott, Jordan Quenneville, Albert Feghaly
Publikováno v:
Nucleic Acids Research. 46:8181-8196
MicroRNAs (miRNAs) are ribonucleic acids (RNAs) of ∼21 nucleotides that interfere with the translation of messenger RNAs (mRNAs) and play significant roles in development and diseases. In bilaterian animals, the specificity of miRNA targeting is de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3071d57f1983654938c5001f0020ce7e
https://doi.org/10.1093/nar/gky546
https://doi.org/10.1093/nar/gky546
Autor:
Albert Feghaly, Yahya Benslimane, Lea Harrington, Mohamed Benhammadi, Claude Perreault, Mathieu Courcelles, Sébastien Lemieux, Tariq Daouda, Maude Dumont-Lagacé, François Major, Yoshua Bengio, Rébecca Panes, Pierre Thibault, Etienne Gagnon
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 10, p e1009482 (2021)
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 10 (2021)
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 10 (2021)
MHC-I associated peptides (MAPs) play a central role in the elimination of virus-infected and neoplastic cells by CD8 T cells. However, accurately predicting the MAP repertoire remains difficult, because only a fraction of the transcriptome generates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87870db4161becf25a846a1452be8b25
https://doi.org/10.1371/journal.pcbi.1009482
https://doi.org/10.1371/journal.pcbi.1009482