Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Albert D. Friesen"'
Autor:
Albert D Friesen, Olivier Thériault, Mohamed Chahine, Hugo Poulin, George Roby Thomas, Waleed A Al-Shaqha
Publikováno v:
Canadian journal of physiology and pharmacology. 92(3)
P2X receptors are cation-permeable ligand-gated ion channels that open in response to the binding of ATP. These receptors are present in many excitable cells, including neurons, striated muscle cells, epithelial cells, and leukocytes. They mediate fa
Autor:
Albert D. Friesen, Elena Duta, Michael I. Anazodo, Jim A. Wright, Mark A. Wainberg, Horacio Salomon
Publikováno v:
Nucleosides and Nucleotides. 16:1241-1249
Fully thioated antisense molecules are often cytotoxic and non-specitic in action. GPI2A is thioated at 7 base positions. GPI2A posses sequence-specific activity against HIV-1 gene expression and viral replication without sigdcant cytotoxicity. Parti
Autor:
Pradip K. Maiti, Howard A. Kaplan, Michael D. Dan, G. Yancey Gillespie, William C. Halliday, Ashok K. Prashar, Xuanmin He, Albert D. Friesen
Publikováno v:
Journal of Neuro-Oncology. 35:93-100
The present study was undertaken to determine thepattern of immunoreactivity of BT32/A6, a human IgMmonoclonal antibody (MAb), with the following histological panels:1) 30 human and non-human cell lines, 2)32 normal human tissues, and 3) 28 tumorsof
Autor:
Ashok K. Prashar, Pradip K. Maiti, Mark C. Griffin, Elizabeth M. Earley, Howard A. Kaplan, Michael D. Dan, Albert D. Friesen, Xin Y. Yuan
Publikováno v:
Journal of Neurosurgery. 82:475-480
✓ The purpose of this study was to ascertain how various growth parameters may influence the labeling of SK-MG-1, a human glioma cell line, by BT32/A6, a human immunoglobulin M monoclonal antibody (MAb). By growing SKMG-1 cells at different culture
Autor:
Euan Burton, Karen Lovetri, Srinivasa Madhyastha, Albert D. Friesen, Purushottam V. Gawande, Nandadeva Yakandawala, George G. Zhanel, Tony Romeo
Publikováno v:
Antimicrobial agents and chemotherapy. 50(5)
The colonization of uropathogenic bacteria on urinary catheters resulting in biofilm formation frequently leads to the infection of surrounding tissue and often requires removal of the catheter. Infections associated with biofilms are difficult to tr
Autor:
Linda Stang, Vinh Pham, Albert D. Friesen, Doug Froese, Ashfaq Shuaib, Tara Whitney, James Diakur, Chen Xu, Wasim Haque, John Yao, Wenlian Zhang
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(18)
The B 6 vitamers have been shown to display beneficial therapeutic effects in cardiovascular related disorders. The design of novel antiplatelet agents using pyridoxine as a template has led to the discovery of a class of novel cardio- and cerebro-pr
Autor:
Vinh Pham, Vince Chen, John Yao, Tara Whitney, James Diakur, Albert D. Friesen, Wasim Haque, Wenlian Zhang, Doug Froese
Publikováno v:
Journal of medicinal chemistry. 46(17)
On the basis of previous reports that the natural cofactor pyridoxal 5'-phosphate 1 appears to display cardioprotective properties, a series of novel mimetics of this cofactor were envisioned. As pyridoxal 5'-phosphate is a natural compound and is su
Publikováno v:
Biochemical and biophysical research communications. 229(1)
GPI2A is a 20-mer antisense oligonucleotide sequence that is complementary to a region of the HIV-1gaggene. An analysis of viral core antigen p24 protein synthesis inhibition was performed with cells expressing HIV-1 proteins, following treatment wit
Autor:
Michael I. Anazodo, Elena Duta, M. Wamberg, Albert D. Friesen, Caiqiong Liu, C. Power, Jim A. Wright
Publikováno v:
Antiviral Research. 34:A63
Publikováno v:
Journal of Food Biochemistry. 13:215-239
Two double-headed isoinhibitors of endogenous alpha-amylase and subtilisin have been purified from triticale by immobilized copper affinity chromatography followed by S-Sepharose Fast Flow ion exchange chromatography and preparative isoelectric focus