Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Albert D Kim"'
Autor:
Qiuyu Guo, Albert D Kim, Bin Li, Andrew Ransick, Helena Bugacov, Xi Chen, Nils O Lindström, Aaron Brown, Leif Oxburgh, Bing Ren, Andrew P McMahon
Publikováno v:
eLife, Vol 10 (2021)
Externí odkaz:
https://doaj.org/article/4a17a71608174361b4325471c7e71eee
Autor:
Lori L O'Brien, Qiuyu Guo, Emad Bahrami-Samani, Joo-Seop Park, Sean M Hasso, Young-Jin Lee, Alan Fang, Albert D Kim, Jinjin Guo, Trudy M Hong, Kevin A Peterson, Scott Lozanoff, Ramya Raviram, Bing Ren, Ben Fogelgren, Andrew D Smith, Anton Valouev, Andrew P McMahon
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007181 (2018)
Nephron progenitor number determines nephron endowment; a reduced nephron count is linked to the onset of kidney disease. Several transcriptional regulators including Six2, Wt1, Osr1, Sall1, Eya1, Pax2, and Hox11 paralogues are required for specifica
Externí odkaz:
https://doaj.org/article/435e97a2f642461e8fa6f0e4415c1cce
Autor:
Zipeng Zeng, Biao Huang, Riana K. Parvez, Yidan Li, Jyunhao Chen, Ariel C. Vonk, Matthew E. Thornton, Tadrushi Patel, Elisabeth A. Rutledge, Albert D. Kim, Jingying Yu, Brendan H. Grubbs, Jill A. McMahon, Nuria M. Pastor-Soler, Kenneth R. Hallows, Andrew P. McMahon, Zhongwei Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here, the authors model the collecting duct system in kidneys by taking ureteric bud (UB) progenitor cells from both mouse and human primary tissues, as well as from hESC and hiPSC to generate organoids, which can model congenital anomalies of the ki
Externí odkaz:
https://doaj.org/article/7d4f8c87de714171bfaad82e1c28c88c
Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter
Autor:
Albert D. Kim, Blue B. Lake, Song Chen, Yan Wu, Jinjin Guo, Riana K. Parvez, Tracy Tran, Matthew E. Thornton, Brendan Grubbs, Jill A. McMahon, Kun Zhang, Andrew P. McMahon
Publikováno v:
iScience, Vol 20, Iss , Pp 402-414 (2019)
Summary: Analysis of kidney disease-causing genes and pathology resulting from systemic diseases highlight the importance of the kidney's filtering system, the renal corpuscles. To elucidate the developmental processes that establish the renal corpus
Externí odkaz:
https://doaj.org/article/995590a1a8c740a0a2777e2e2dff5922
Autor:
Núria M. Pastor-Soler, Albert D. Kim, Riana K. Parvez, Kenneth R. Hallows, Zhongwei Li, Jill A. McMahon, Tadrushi Patel, Ariel Vonk, Zipeng Zeng, Yidan Li, Matthew E. Thornton, Jingying Yu, Biao Huang, Jyunhao Chen, Elisabeth A. Rutledge, Andrew P. McMahon, Brendan H. Grubbs
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Current kidney organoids model development and diseases of the nephron but not the contiguous epithelial network of the kidney’s collecting duct (CD) system. Here, we report the generation of an expandable, 3D branching ureteric bud (UB) organoid c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e791ec4e333f3bb48ea1f6de3ab9e21
https://doi.org/10.1038/s41467-021-23911-5
https://doi.org/10.1038/s41467-021-23911-5
Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter
Autor:
Matthew E. Thornton, Brendan H. Grubbs, Yan Wu, Andrew P. McMahon, Blue B. Lake, Jinjin Guo, Jill A. McMahon, Riana K. Parvez, Song Chen, Kun Zhang, Tracy S. Tran, Albert D. Kim
Publikováno v:
iScience, Vol 20, Iss, Pp 402-414 (2019)
iScience
iScience
Summary Analysis of kidney disease-causing genes and pathology resulting from systemic diseases highlight the importance of the kidney's filtering system, the renal corpuscles. To elucidate the developmental processes that establish the renal corpusc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c021b04d8e50f9f7bfb3b62d78239b3a
http://www.sciencedirect.com/science/article/pii/S2589004219303670
http://www.sciencedirect.com/science/article/pii/S2589004219303670
Autor:
Andrew P. McMahon, Jinjin Guo, Andrew Ransick, Jill A. McMahon, Alicja Tadych, Olga G. Troyanskaya, Jian Zhou, Xi Chen, Rachel Sealfon, Andrew D. Smith, Bill Hill, Seth Ruffins, Riana K. Parvez, Tracy S. Tran, Elizabeth Lovero, Aaron Watters, Aaron B. Wong, Nils O. Lindström, Brendan H. Grubbs, Chris Armit, Albert D. Kim, Guilherme De Sena Brandine, Matthew E. Thornton
Publikováno v:
Dev Cell
SummaryCongenital abnormalities of the kidney and urinary tract are amongst the most common birth defects affecting 3% of newborns. The human kidney develops over a 30-week period in which a nephron progenitor pool gives rise to around a million neph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7298ade961250a887bfab3bcea4b75
Autor:
Núria M. Pastor-Soler, Yidan Li, Brendan H. Grubbs, Zhongwei Li, Jingying Yu, Riana K. Parvez, Jill A. McMahon, Jyunhao Chen, Zipeng Zeng, Andrew P. McMahon, Albert D. Kim, Kenneth R. Hallows, Ariel Vonk, Tadrushi Patel, Elisabeth A. Rutledge, Matthew E. Thornton, Biao Huang
Kidney organoids model development and diseases of the nephron but not the contiguous epithelial network of the kidney’s collecting duct (CD) system. Here, we report the generation of an expandable, 3D branching ureteric bud (UB) organoid culture m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a80ea71674b8ac413bcc82ee0c1a4e
https://doi.org/10.1101/2020.04.27.049031
https://doi.org/10.1101/2020.04.27.049031
Autor:
Andrew P. McMahon, Jinjin Guo, Ahmed Abdelhalim, Robert Schuler, Qiuyu Guo, Carl Kesselman, Matthew E. Thornton, Jill A. McMahon, Riana K. Parvez, Christopher D. Liao, Albert D. Kim, Laurence Basking, Elisabeth A. Rutledge, Tracy S. Tran, Gohar Saribekyan, Brendan H. Grubbs, Seth Ruffins, Nils O. Lindström
Publikováno v:
Journal of the American Society of Nephrology. 29:785-805
Human kidney function is underpinned by approximately 1,000,000 nephrons, although the number varies substantially, and low nephron number is linked to disease. Human kidney development initiates around 4 weeks of gestation and ends around 34-37 week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa71f93e74b15dd337bc0dd80d55b957
https://doi.org/10.1681/asn.2017080887
https://doi.org/10.1681/asn.2017080887
Autor:
Hannah G. Black, Andrew P. McMahon, Jinjin Guo, Andrew Ransick, Jing Liu, Albert D. Kim, Junhyong Kim, Gregory F. Alvarado, Qin Zhu, Nils O. Lindström
SummaryChronic kidney disease affects 10% of the population with notable differences in ethnic and sex-related susceptibility to kidney injury and disease. Kidney dysfunction leads to significant morbidity and mortality, and chronic disease in other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e52d97a50e167c5b579a9dab392a016
https://doi.org/10.1101/673335
https://doi.org/10.1101/673335