Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Albert C.M. Ong"'
Autor:
Ronald D. Perrone, Dorothee Oberdhan, John Ouyang, Daniel G. Bichet, Klemens Budde, Arlene B. Chapman, Berenice Y. Gitomer, Shigeo Horie, Albert C.M. Ong, Vicente E. Torres, A. Neil Turner, Holly Krasa
Publikováno v:
Kidney International Reports, Vol 8, Iss 5, Pp 989-1001 (2023)
Introduction: The course of autosomal dominant polycystic kidney disease (ADPKD) varies greatly among affected individuals, necessitating natural history studies to characterize the determinants and effects of disease progression. Therefore, we condu
Externí odkaz:
https://doaj.org/article/6263893d07674a6789c237002dc53cb4
Autor:
Ronald D. Perrone, Ali Hariri, Pascal Minini, Curie Ahn, Arlene B. Chapman, Shigeo Horie, Bertrand Knebelmann, Michal Mrug, Albert C.M. Ong, York P.C. Pei, Vicente E. Torres, Vijay Modur, Ronald T. Gansevoort
Publikováno v:
Kidney Medicine, Vol 4, Iss 10, Pp 100538- (2022)
Rationale & Objective: Venglustat, a glucosylceramide synthase inhibitor, inhibits cyst growth and reduces kidney failure in mouse models of autosomal dominant polycystic kidney disease (ADPKD). STAGED-PKD aims to determine the safety and efficacy of
Externí odkaz:
https://doaj.org/article/66ff3b0e6417477da59ccf6a9cdbba1d
Autor:
Roman-Ulrich Müller, A. Lianne Messchendorp, Henrik Birn, Giovambattista Capasso, Emilie Cornec-Le Gall, Olivier Devuyst, Albertien van Eerde, Patrick Guirchoun, Tess Harris, Ewout J. Hoorn, Nine V.A.M. Knoers, Uwe Korst, Djalila Mekahli, Yannick Le Meur, Tom Nijenhuis, Albert C.M. Ong, John A. Sayer, Franz Schaefer, Aude Servais, Vladimir Tesar, Roser Torra, Stephen B. Walsh and Ron T. Gansevoort
Publikováno v:
Počki, Vol 11, Iss 1, Pp 37-39 (2022)
No abstract
Externí odkaz:
https://doaj.org/article/3f3763f45a78472d9048eb2d6d9503c1
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
Mutations in PKD1 (encoding for polycystin-1 [PC1]) are found in 80%–85% of patients with autosomal dominant polycystic kidney disease (ADPKD). We tested the hypothesis that changes in actin dynamics result from PKD1 mutations through dysregulation
Externí odkaz:
https://doaj.org/article/5a9969d7d28a4e509127941488dce554
Publikováno v:
Clinical Kidney Journal
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of end-stage kidney failure. At present, only one drug, tolvaptan, has been approved for use to slow disease progression, but its use is limited by reduced tolera
Autor:
Albert C.M. Ong, Ron T. Gansevoort
Publikováno v:
Kidney Int
Kidney International, 100(3), 513-515. ELSEVIER SCIENCE INC
Kidney International, 100(3), 513-515. ELSEVIER SCIENCE INC
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by growth of kidney cysts and glomerular filtration rate (GFR) decline. Metformin was found to impact cystogenesis in preclinical models of polycystic disease, is generally conside
Publikováno v:
Renal Failure
article-version (VoR) Version of Record
Renal Failure, Vol 43, Iss 1, Pp 1-15 (2021)
article-version (VoR) Version of Record
Renal Failure, Vol 43, Iss 1, Pp 1-15 (2021)
Objectives\ud \ud A meta-analysis and systematic review was conducted on kidney-related outcomes of three recent pandemics: SARS, MERS, and COVID-19, which were associated with potentially fatal acute respiratory distress syndrome (ARDS).\ud \ud \ud
Autor:
Huamu Chen, Min Li, Xuefei Gao, Dantong Li, Xiaohong Wu, Miaoyue Hu, Liangzhong Sun, Haiyan Wang, Zhihui Yue, Albert C.M. Ong, Xiaoya Wei, Hongrong Lin
Nephronophthisis (NPH) is the most prevalent monogenetic disorder leading to end-stage renal failure (ESRD) in childhood. Mutations in Nphp1, encoding a cilia-localized protein, account for the majority of NPH cases. Despite its identification many y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2f1e92a0607c6ac444b064fb785ce5
Autor:
Albertien M. van Eerde, Miguel Barroso-Gil, Fouad T. Chebib, Yannick Le Meur, Vinh Toan Huynh, Andrew Mallett, Amali Mallawaarachchi, Marc Kribs, Himanshu Goel, Eléonore Ponlot, Chirag Patel, John A. Sayer, Albert C.M. Ong, Marie-Pierre Audrézet, Peter C. Harris, Siriane Lefevre, Sarah R. Senum, Valoris Le Brun, Emilie Cornec-Le Gall, Aurore Després
Publikováno v:
Kidney International
Kidney International, Nature Publishing Group, 2020, 98, pp.476-487. ⟨10.1016/j.kint.2020.02.022⟩
Kidney Int
Kidney International, Nature Publishing Group, 2020, 98, pp.476-487. ⟨10.1016/j.kint.2020.02.022⟩
Kidney Int
Monoallelic mutations of DNAJB11 were recently described in seven pedigrees with atypical clinical presentations of autosomal dominant polycystic kidney disease. DNAJB11 encodes one of the main cofactors of the endoplasmic reticulum chaperon BiP, a h
Autor:
Mónica Furlano, Jean Winterbottom, Nathalie Demoulin, Emilie Cornec-Le Gall, Esther Meijer, Roser Torra, Olivier Devuyst, Roslyn J. Simms, Anna Caroli, Albert C.M. Ong, Ron T. Gansevoort, Norberto Perico, Yannick LeMeur
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims ADPKD is the most common inherited kidney disease in man, a major cause of end-stage renal disease and is a significant medical and economic burden worldwide. However, the impact of this major disease on the quality of life of pat