Výsledky vyhledávání - "Albert Bilos"

Akademický článek

Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates

Autor: Maarten van der Velden, Albert Bilos, Jeroen J. M. W. van den Heuvel, Sanna R. Rijpma, Evelien G. E. Hurkmans, Robert W. Sauerwein, Frans G. M. Russel, Jan B. Koenderink

Publikováno v: Malaria Journal, Vol 16, Iss 1, Pp 1-12 (2017)

Abstract Background Malaria, HIV/AIDS, and tuberculosis endemic areas show considerable geographical overlap, leading to incidence of co-infections. This requires treatment with multiple drugs, potentially causing adverse drug–drug interactions (DD

Externí odkaz: https://doaj.org/article/b27f86145f49479db057cc1f0f96e3c4

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Akademický článek

The effect of eplerenone on adenosine formation in humans in vivo: a double-blinded randomised controlled study.

Autor: T N A van den Berg, Jaap Deinum, Albert Bilos, A Rogier T Donders, Gerard A Rongen, Niels P Riksen

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e111248 (2014)

It has been suggested that mineralocorticoid receptor antagonists have direct cardioprotective properties, because these drugs reduce mortality in patients with heart failure. In murine models of myocardial infarction, mineralocorticoid receptor anta

Externí odkaz: https://doaj.org/article/757cbe05964348a9a1bd92491a0cd489

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Editor’s Highlight: Placental Disposition and Effects of Crizotinib: An Ex Vivo Study in the Isolated Dual-Side Perfused Human Cotyledon

Autor: Joris van Drongelen, Gaby A M Eliesen, Petra H.H. van den Broek, Albert Bilos, Rick Greupink, Jeanne Pertijs, Jeroen J. van den Heuvel, Frans G. M. Russel

Publikováno v: Toxicological Sciences. 157:500-509

Tyrosine kinase inhibitors (TKIs) play an important role in cancer pharmacotherapy, yet there is limited data on their use during pregnancy. We studied placental disposition and placental toxicity of crizotinib, a TKI used to treat nonsmall cell lung

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eac6abab466b121e6bef41cf9e6038e
https://doi.org/10.1093/toxsci/kfx063

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Effect of two dosages of sodium chloride intake on the blood pressure response to caffeinated coffee in humans in vivo

Autor: Niels P. Riksen, Anne C. Esselink, Lisanne M Bril, Renée W Langenhuijsen, Albert Bilos, Gerard A. Rongen

Publikováno v: International Journal of Food Sciences and Nutrition, 70, 1014-1019
International Journal of Food Sciences and Nutrition, 70, 8, pp. 1014-1019

Contains fulltext : 208798.pdf (Publisher’s version ) (Open Access) High sodium intake increases cardiovascular risk by increasing blood pressure. The intake of coffee elevates blood pressure acutely. Preclinical evidence shows that this action of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd21ab045f40eec0555f11895788cf3
http://hdl.handle.net/2066/208798

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MRP1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum

Autor: Maarten van der Velden, Jan B. Koenderink, Robert W. Sauerwein, Albert Bilos, Koen van de Wetering, Sanna R. Rijpma, Frans G. M. Russel, Sunny Mahakena, Robert S. Jansen

Publikováno v: FEBS Letters, 590, 482-92
FEBS Letters, 590, 4, pp. 482-92

Contains fulltext : 170847.pdf (Publisher’s version ) (Closed access) Multidrug resistance-associated proteins (MRP) of Plasmodium falciparum have been associated with altered drug sensitivity. Knowledge on MRP substrate specificity is indispensibl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00aabd291bf00d3edfa2be3ee0fa2af6
https://hdl.handle.net/2066/170847

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Vascular and metabolic effects of the haem oxygenase-1 inducer haem arginate in subjects with the metabolic syndrome: A translational cross-over study

Autor: Paul Smits, Sebastiaan W C Pennings, Wilbert H.M. Peters, Frank A. D. T. G. Wagener, Mirrin J. Dorresteijn, Albert Bilos, Douwe Dekker

Publikováno v: Diabetes and Vascular Disease Research, 13(1), 41. SAGE Publications Ltd
Diabetes & Vascular Disease Research, 13, 1, pp. 41-8
Diabetes & Vascular Disease Research, 13, 41-8

Item does not contain fulltext This translational randomized and vehicle-controlled cross-over study was performed to assess the impact of haem arginate treatment on haem oxygenase-1 induction, endothelial function and insulin sensitivity in subjects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df67f3f583c84fa1d9be9c832fc9f67a
https://hdl.handle.net/2066/171925

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Statin Lactonization by Uridine 5′-Diphospho-glucuronosyltransferases (UGTs)

Autor: Tom J.J. Schirris, Frans G. M. Russel, Albert Bilos, Tina Ritschel, Jan A.M. Smeitink

Publikováno v: Molecular Pharmaceutics, 12, 4048-55
Molecular Pharmaceutics, 12, 11, pp. 4048-55

Contains fulltext : 152742.pdf (Publisher’s version ) (Closed access) Statins are cholesterol-lowering drugs that have proven to be effective in lowering the risk of major cardiovascular events. Although well tolerated, statin-induced myopathies ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928b0fc434d1c36f8beb8844ac217198
https://doi.org/10.1021/acs.molpharmaceut.5b00474

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Alkaline phosphatase protects against renal inflammation through dephosphorylation of lipopolysaccharide and adenosine triphosphate

Autor: Rosalinde Masereeuw, Stefania Geraci, Albert Bilos, Martijn J. Wilmer, Peter Pickkers, B Kraenzlin, Norbert Gretz, Suzanne Heemskerk, Esther Peters

Publikováno v: British Journal of Pharmacology. 172:4932-4945

BACKGROUND AND PURPOSE: Recently, two phase-II trials demonstrated improved renal function in critically ill patients with sepsis-associated acute kidney injury treated with the enzyme alkaline phosphatase. Here, we elucidated the dual active effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f2eb1868f6fc2d6205ed82a4f28d0d8
https://doi.org/10.1111/bph.13261

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Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

Autor: Julien Beyrath, Jan A.M. Smeitink, Werner J.H. Koopman, Ulrich Brandt, Richard J. Rodenburg, G. Herma Renkema, Nicol C. Voermans, Peter H.G.M. Willems, Albert Bilos, Tina Ritschel, Tom J.J. Schirris, Baziel G.M. van Engelen, Frans G. M. Russel

Publikováno v: Cell Metabolism, 22, 3, pp. 399-407
Cell Metabolism, 22, 399-407

Contains fulltext : 154004.pdf (Publisher’s version ) (Closed access) Cholesterol-lowering statins effectively reduce the risk of major cardiovascular events. Myopathy is the most important adverse effect, but its underlying mechanism remains enigm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb3ae4355702b991b4da6c4df878dd0

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Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol

Autor: Jan B. Koenderink, Reinout van Crevel, Albert Bilos, Rob E. Aarnoutse, Lindsey H.M. te Brake, Aaron Ohene Buaben, Jeroen J. M. W. van den Heuvel, Frans G. M. Russel

Publikováno v: Antimicrobial Agents and Chemotherapy, 60, 7105-7114
Antimicrobial Agents and Chemotherapy, 60, 12, pp. 7105-7114

It is largely unknown if simultaneous administration of tuberculosis (TB) drugs and metformin leads to drug-drug interactions (DDIs). Disposition of metformin is determined by organic cation transporters (OCTs) and multidrug and toxin extrusion prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a62de5f6d66cf86506def2410d0363d
https://pubmed.ncbi.nlm.nih.gov/27645247

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