EFFECTS OF ANTIDEPRESSANT TREATMENT ON BEHAVIOR, LIPIDOME, AND MITOCHONDRIAL ACTIVITY OF DIFFERENT RAT BRAIN AREAS.

Autor: Ekaterina Noskova, Roberto Fernández, Egoitz Astigarraga, Albert Adell, Gabriel Barreda-Gómez

Publikováno v: IBRO Neuroscience Reports, Vol 15, Iss , Pp S619- (2023)

Externí odkaz: https://doaj.org/article/3e96c6e464ed4fab9643fcdff34dea3e

Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT1A Receptor Biased Agonist

Autor: Sharon Cabanu, Fuencisla Pilar-Cuéllar, Paula Zubakina, Eva Florensa-Zanuy, Júlia Senserrich, Adrian Newman-Tancredi, Albert Adell

Publikováno v: Pharmaceuticals, Vol 15, Iss 3, p 337 (2022)

Depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-HT) is considered to be the major neurotransmitter involved in its etiology and treatment. In this context, 5-HT1A receptors have attracted interest as tar

Externí odkaz: https://doaj.org/article/57a3290157564379bb93367a54345fe3

Characterization of the Antitumor Potential of Extracts of Cannabis sativa Strains with High CBD Content in Human Neuroblastoma

Autor: Laura Sánchez-Sánchez, Javier García, Roberto Fernández, Ekaterina Noskova, June Egiguren-Ortiz, Marina Gulak, Eneko Ochoa, Antonio Laso, Mikel Oiarbide, José Ignacio Santos, María Fe Andrés, Azucena González-Coloma, Albert Adell, Egoitz Astigarraga, Gabriel Barreda-Gómez

Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3837

Cannabis has been used for decades as a palliative therapy in the treatment of cancer. This is because of its beneficial effects on the pain and nausea that patients can experience as a result of chemo/radiotherapy. Tetrahydrocannabinol and cannabidi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db5d793c867d93c7d320dfb7feb5ee1
http://hdl.handle.net/10810/60113

Structural connectivity and subcellular changes after antidepressant doses of ketamine and Ro 25-6981 in the rat: an MRI and immuno-labeling study

Autor: Arantxa Blasco-Serra, Emma Muñoz-Moreno, Fuencisla Pilar-Cuéllar, Albert Adell, Raquel Pascual-Antón, Guadalupe Soria, Emilio Garro-Martínez, Víctor M Campa, Eva Florensa-Zanuy, Xavier López-Gil

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Brain Struct Funct . 2021 Nov;226(8):2603-2616
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Brain Structure & Function

© The Author(s) 2021.
Ketamine has rapid and robust antidepressant effects. However, unwanted psychotomimetic effects limit its widespread use. Hence, several studies examined whether GluN2B-subunit selective NMDA antagonists would exhibit a be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ed966472ea1376252ac603adfb6046
https://doi.org/10.1007/s00429-021-02354-0

β-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System

Autor: Fuencisla Pilar-Cuéllar, Emilio Garro-Martínez, Rebeca Vidal, Josep Amigó, Albert Adell, Elena Castro, Laura Gómez-Acero, Raquel Gutiérrez-Lanza, Álvaro Díaz, Angel Pazos, Eva Florensa-Zanuy, Makoto Mark Taketo

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

We previously reported that the inactivation (cKO) or the stabilization (cST) of β-catenin in cells expressing the astrocyte-specific glutamate aspartate transporter (GLAST) is associated with the vulnerability or resilience to exhibit anxious/depre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccf49ed50c347fe94eb7630841674bc
https://doi.org/10.1007/s12035-019-01841-0