Zobrazeno 1 - 10 of 86 pro vyhledávání: '"Albert A. Hagège"'
1
Akademický článek
Dosing and Safety Profile of Aficamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy: Results From SEQUOIA‐HCM
Autor: Caroline J. Coats, Ahmad Masri, Michael E. Nassif, Roberto Barriales‐Villa, Michael Arad, Nuno Cardim, Lubna Choudhury, Brian Claggett, Hans‐Dirk Düngen, Pablo Garcia‐Pavia, Albert A. Hagège, James L. Januzzi, Matthew M. Y. Lee, Gregory D. Lewis, Chang‐Sheng Ma, Martin S. Maron, Zi Michael Miao, Michelle Michels, Iacopo Olivotto, Artur Oreziak, Anjali T. Owens, John A. Spertus, Scott D. Solomon, Jacob Tfelt‐Hansen, Marion van Sinttruije, Josef Veselka, Hugh Watkins, Daniel L. Jacoby, Polina German, Stephen B. Heitner, Stuart Kupfer, Justin D. Lutz, Fady I. Malik, Lisa Meng, Amy Wohltman, Theodore P. Abraham
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Aficamten, a novel cardiac myosin inhibitor, reversibly reduces cardiac hypercontractility in obstructive hypertrophic cardiomyopathy. We present a prespecified analysis of the pharmacokinetics, pharmacodynamics, and safety of aficamten in
Externí odkaz: https://doaj.org/article/ecd7f5b3949f4a8ca276c42cd7292a3f
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2
Akademický článek
Targeted Mybpc3 Knock-Out Mice with Cardiac Hypertrophy Exhibit Structural Mitral Valve Abnormalities
Autor: Daniel P. Judge, Hany Neamatalla, Russell A. Norris, Robert A. Levine, Jonathan T. Butcher, Nicolas Vignier, Kevin H. Kang, Quangtung Nguyen, Patrick Bruneval, Marie-Cécile Perier, Emmanuel Messas, Xavier Jeunemaitre, Annemarieke de Vlaming, Roger Markwald, Lucie Carrier, Albert A. Hagège
Publikováno v: Journal of Cardiovascular Development and Disease, Vol 2, Iss 2, Pp 48-65 (2015)
MYBPC3 mutations cause hypertrophic cardiomyopathy, which is frequently associated with mitral valve (MV) pathology. We reasoned that increased MV size is caused by localized growth factors with paracrine effects. We used high-resolution echocardiogr
Externí odkaz: https://doaj.org/article/e53b289b975d48c5bc0807cfeddadbdc
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3
Akademický článek
Long-Term Functional Benefits of Epicardial Patches as Cell Carriers
Autor: Hadhami Hamdi, Valérie Planat-Benard, Alain Bel, Hany Neamatalla, Laetitia Saccenti, Damelys Calderon, Valérie Bellamy, Martin Bon, Marie-Cécile Perrier, Chantal Mandet, Patrick Bruneval, Louis Casteilla, Albert A. Hagège, Michel Pucéat, Onnik Agbulut, Philippe Menasché
Publikováno v: Cell Transplantation, Vol 23 (2014)
Both enzymatic dissociation of cells prior to needle-based injections and poor vascularization of myocardial infarct areas are two important contributors to cell death and impede the efficacy of cardiac cell therapy. Because these limitations could b
Externí odkaz: https://doaj.org/article/0258de226aaf4f84869c56b87cf5f5f4
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4
Development of the Hypertrophic Cardiomyopathy Symptom Questionnaire (HCMSQ): A New Patient-Reported Outcome (PRO) Instrument
Autor: Matthew Reaney, Veleka Allen, Amy J. Sehnert, Liang Fang, Albert A. Hagège, Srihari S. Naidu, Iacopo Olivotto
Publikováno v: PharmacoEconomics - Open. 6:563-574
Currently, there is no patient-reported outcome (PRO) instrument specifically designed to evaluate hypertrophic cardiomyopathy (HCM).We present the development and psychometric validation of a novel PRO measure, the HCM Symptom Questionnaire version
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f3d7bdd71296f3b35837b8f71c845f
https://doi.org/10.1007/s41669-022-00335-5
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5
Aetiological classification and prognosis in patients with heart failure with preserved ejection fraction
Autor: Orianne Domengé, Albert A. Hagège, Michel Azizi, Etienne Puymirat, Elie Mousseaux, Mariana Mirabel, Laurence Amar, Anne-Sophie Jannot, Jean-Sébastien Hulot, Jean-Baptiste Carves, Eva Vermersch, Anne Blanchard, Claire Carette, Maxime Wack, Marine Livrozet, Julien Le Guen, Alexandre Karras, Marie-Cécile Bories, Antoine Fayol
Publikováno v: ESC Heart Failure, Vol 9, Iss 1, Pp 519-530 (2022)
ESC Heart Failure
ESC Heart Failure, Wiley, 2021, ⟨10.1002/ehf2.13717⟩
ESC Heart Failure, 2022, 9 (1), pp.519-530. ⟨10.1002/ehf2.13717⟩
ESC Heart Failure, 2021, ⟨10.1002/ehf2.13717⟩
Aims Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome with various causes that may influence prognosis. Methods and results We extracted the electronic medical records for 2180 consecutive patients hospitalized betwe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712039f2f019869102a06d791a8a26f0
https://doaj.org/article/5f158428d0644d99951a0bf7aa7cd91c
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7
Genome-wide association meta-analysis supports genes involved in valve and cardiac development to associate with mitral valve prolapse
Autor: Russell A. Norris, Albert A. Hagège, Nabila Bouatia-Naji, Jean-Jacques Schott, Sergiy Kyryachenko, Xavier Jeunemaitre, Philippe Amouyel, Stéphanie Debette, Thierry Le Tourneau, Mengyao Yu, Christian Dina
Publikováno v: Circulation-Genomic and Precision Medicine
Circulation-Genomic and Precision Medicine, 2021, 14 (5), pp.CIRCGEN120003148. ⟨10.1161/CIRCGEN.120.003148⟩
Circ Genom Precis Med
ObjectiveMitral valve prolapse (MVP) is a common cardiac valve disease, which affects 1 in 40 in the general population. Previous GWAS have identified six risk loci for MVP. But these loci explained only partially the genetic risk for MVP. We aim to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9832771b54a64d550694ec1d34f809f
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8
In vitro controlled release of extracellular vesicles for cardiac repair from poly(glycerol sebacate) acrylate-based polymers
Autor: Julie L.N. Dubois, Thomas Hamada, Maria N. Pereira, Philippe Menasché, Albert A. Hagège, Valérie Bellamy, Laetitia Pidial
Publikováno v: Acta Biomaterialia
Acta Biomaterialia, Elsevier, 2020, 115, pp.92-103. ⟨10.1016/j.actbio.2020.08.015⟩
International audience; Cell therapy to restore cardiac function in chronic heart failure has been extensively studied. However, its therapeutic value is limited due to poor cell engraftment and survival and the therapeutic outcomes have been attribu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2dfe757f293b3457e15deb029d9cbe
https://pubmed.ncbi.nlm.nih.gov/32814141
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10
Risk of atrial fibrillation in hypertrophic cardiomyopathy: A clustering analysis based on the French registry on hypertrophic cardiomyopathy (REMY)
Autor: Guillaume Bouzillé, Patricia Reant, Fabien Labombarda, Albert A. Hagège, Thibaud Damy, M. Hourqueig, J-C Eicher, Gilbert Habib, Mariana Mirabel, Erwan Donal, Olivier Huttin, P. Charron
Publikováno v: Archives of Cardiovascular Diseases Supplements. 13:21-22
Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): CHU Rennes, Inserm, LTSI – UMR 1099, F-35000 Rennes, France Assistance Publique-Hôpitaux de Paris-Centre Université de Paris, University of Paris onbeha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c8bac57052d36a803e92648fa8f1d9
https://doi.org/10.1016/j.acvdsp.2020.10.082
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