Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Albert, Salehi"'
Autor:
Israa Mohammad Al-Amily, Marie Sjögren, Pontus Duner, Mohammad Tariq, Claes B. Wollheim, Albert Salehi
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 557 (2023)
The activation of G Protein-Coupled Receptor 56 (GPR56), also referred to as Adhesion G-Protein-Coupled Ceceptor G1 (ADGRG1), by Collagen Type III (Coll III) prompts cell growth, proliferation, and survival, among other attributes. We investigated th
Externí odkaz:
https://doaj.org/article/f25366dd43244619aa0b89add67b5c83
Autor:
Elisa Vergari, Jakob G. Knudsen, Reshma Ramracheya, Albert Salehi, Quan Zhang, Julie Adam, Ingrid Wernstedt Asterholm, Anna Benrick, Linford J. B. Briant, Margarita V. Chibalina, Fiona M. Gribble, Alexander Hamilton, Benoit Hastoy, Frank Reimann, Nils J. G. Rorsman, Ioannis I. Spiliotis, Andrei Tarasov, Yanling Wu, Frances M. Ashcroft, Patrik Rorsman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Impaired glucagon secretion in patients with diabetes causes hypoglycemia. Here the authors show that therapeutic concentrations of insulin inhibit alpha-cell glucagon secretion by stimulating delta-cell insulin receptor and the release of somatostat
Externí odkaz:
https://doaj.org/article/9d4aeee6ff1d49cdae2f6687f5fe8637
Autor:
Davide Basco, Quan Zhang, Albert Salehi, Andrei Tarasov, Wanda Dolci, Pedro Herrera, Ioannis Spiliotis, Xavier Berney, David Tarussio, Patrik Rorsman, Bernard Thorens
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Glucagon secretion is promoted during hypoglycemia and inhibited by increased glucose levels. Here, Basco et al. show that glucokinase suppresses glucose-regulated glucagon secretion by modulating the intracellular ATP/ADP ratio and the closure of KA
Externí odkaz:
https://doaj.org/article/0248c76c4524407a805ca6e24356aff3
Autor:
Hayat Aljaibeji, Debasmita Mukhopadhyay, Abdul Khader Mohammed, Sarah Dhaiban, Mahmood Y. Hachim, Noha M. Elemam, Nabil Sulaiman, Albert Salehi, Jalal Taneera
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Previous work has shown that reduced expression of PLCXD3, a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin secretion with an unclear mechanism. In the current study, we aim to investigate the mechanism under
Externí odkaz:
https://doaj.org/article/55019bc111574dcb8c6929f5a1fa0aee
Autor:
Amjad Ali, Hema Unnikannan, Jasmin Shafarin, Khuloud Bajbouj, Jalal Taneera, Jibran Sualeh Muhammad, Haydar Hasan, Albert Salehi, Samir Awadallah, Mawieh Hamad
Publikováno v:
Endocrine. 76:543-557
Metformin (MF) intake associates with reduced levels of circulating low-density lipoprotein-cholesterol (LDL-C). This has been attributed to the activation of AMPK, which differentially regulates the expression of multiple genes involved in cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c90072672b27b057bf3d6492e952640
https://doi.org/10.1007/s12020-022-03022-x
https://doi.org/10.1007/s12020-022-03022-x
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165668 (2016)
Metformin lowers diabetic blood glucose primarily by reducing hepatic gluconeogenesis and increasing peripheral glucose uptake. However, possible effects by metformin on beta-cell function are incompletely understood. We speculated that metformin mig
Externí odkaz:
https://doaj.org/article/1cf2ed1499484ae7b6ff84813beb8665
Publikováno v:
Pflugers Archiv
We have recently shown that the G protein-coupled receptor 142 (GPR142) is expressed in both rodent and human pancreatic β-cells. Herein, we investigated the cellular distribution of GPR142 within islets and the effects of selective agonists of GPR1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afcdad5e2ff03f278bf317985f9311c
https://doi.org/10.1007/s00424-019-02262-7
https://doi.org/10.1007/s00424-019-02262-7
Autor:
Inga Prokopenko, Wenny Poon, Reedik Mägi, Rashmi Prasad B, S Albert Salehi, Peter Almgren, Peter Osmark, Nabila Bouatia-Naji, Nils Wierup, Tove Fall, Alena Stančáková, Adam Barker, Vasiliki Lagou, Clive Osmond, Weijia Xie, Jari Lahti, Anne U Jackson, Yu-Ching Cheng, Jie Liu, Jeffrey R O'Connell, Paul A Blomstedt, Joao Fadista, Sami Alkayyali, Tasnim Dayeh, Emma Ahlqvist, Jalal Taneera, Cecile Lecoeur, Ashish Kumar, Ola Hansson, Karin Hansson, Benjamin F Voight, Hyun Min Kang, Claire Levy-Marchal, Vincent Vatin, Aarno Palotie, Ann-Christine Syvänen, Andrea Mari, Michael N Weedon, Ruth J F Loos, Ken K Ong, Peter Nilsson, Bo Isomaa, Tiinamaija Tuomi, Nicholas J Wareham, Michael Stumvoll, Elisabeth Widen, Timo A Lakka, Claudia Langenberg, Anke Tönjes, Rainer Rauramaa, Johanna Kuusisto, Timothy M Frayling, Philippe Froguel, Mark Walker, Johan G Eriksson, Charlotte Ling, Peter Kovacs, Erik Ingelsson, Mark I McCarthy, Alan R Shuldiner, Kristi D Silver, Markku Laakso, Leif Groop, Valeriya Lyssenko
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004235 (2014)
Variants in the growth factor receptor-bound protein 10 (GRB10) gene were in a GWAS meta-analysis associated with reduced glucose-stimulated insulin secretion and increased risk of type 2 diabetes (T2D) if inherited from the father, but inexplicably
Externí odkaz:
https://doaj.org/article/426bbcbc38894f88b836facbc9420ecc
Autor:
Pontus, Duner, Albert, Salehi
Publikováno v:
Journal of Clinical Medicine Research
The dreadful fear of the coronavirus disease 2019 (COVID-19), which is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with the deadly consequences, requires rapid development of pharmacological cures. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b9c6e39bba9ee57c23203e1aa4b4f96
https://pubmed.ncbi.nlm.nih.gov/33447309
https://pubmed.ncbi.nlm.nih.gov/33447309
Autor:
Jalal Taneera, Mahmood Y. Hachim, Albert Salehi, Hayat Aljaibeji, Rifat Hamoudi, Ibrahim Y. Hachim, Noha Mousaad Elemam, Abdul Khader Mohammed, Nabil Sulaiman
Publikováno v:
Genes
Genes, Vol 11, Iss 461, p 461 (2020)
Volume 11
Issue 4
Genes, Vol 11, Iss 461, p 461 (2020)
Volume 11
Issue 4
The United Arab Emirates National Diabetes and Lifestyle Study (UAEDIAB) has identified obesity, hypertension, obstructive sleep apnea, and dyslipidemia as common phenotypic characteristics correlated with diabetes mellitus status. As these phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070e312363569f06dfad870684116881
http://europepmc.org/articles/PMC7230604
http://europepmc.org/articles/PMC7230604