Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Albert, J Becker"'
Autor:
Daniel S. Galvis-Montes, Karen M. J. van Loo, Ashley J. van Waardenberg, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Transient brain insults including status epilepticus (SE) can initiate a process termed ‘epileptogenesis’ that results in chronic temporal lobe epilepsy. As a consequence, the entire tri-synaptic circuit of the hippocampus is fundamental
Externí odkaz:
https://doaj.org/article/2d824e767dd14c728075aa14d652228a
Autor:
Philipp Müller, Dirk Dietrich, Susanne Schoch, Julika Pitsch, Albert J. Becker, Silvia Cases-Cunillera
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106364- (2024)
Gangliogliomas (GGs) represent the most frequent glioneuronal tumor entity associated with chronic recurrent seizures; rare anaplastic GGs variants retain the glioneuronal character. So far, key mechanisms triggering chronic hyperexcitability in the
Externí odkaz:
https://doaj.org/article/ab464e022fb04863b4ddb1e4bca64b6c
Autor:
Amira Sayed Hanafy, Pia Steinlein, Julika Pitsch, Mariella Hurtado Silva, Natascha Vana, Albert J. Becker, Mark Evan Graham, Susanne Schoch, Alf Lamprecht, Dirk Dietrich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The blood-brain barrier (BBB) tightly and dynamically regulates exchange with the brain. Here, the authors report a brain slice approach to study the native BBB in a highly controlled manner by combining intravascular perfusion and multiphoton micros
Externí odkaz:
https://doaj.org/article/4cb633c9c9004c6bbbdb5c97f9e673c4
Autor:
Andre Dik, Guido Widman, Andreas Schulte‐Mecklenbeck, Juri‐Alexander Witt, Julika Pitsch, Kristin S. Golombeck, Jan Wagner, Marco Gallus, Christine Strippel, Niels Hansen, Constanze Mönig, Saskia Räuber, Heinz Wiendl, Christian E. Elger, Rainer Surges, Sven G. Meuth, Christoph Helmstaedter, Catharina C. Gross, Albert J. Becker, Nico Melzer
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 12, Pp 2289-2301 (2021)
Abstract Objective Direct pathogenic effects of autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GAD65) in autoimmune limbic encephalitis (LE) have been questioned due to its intracellular localization. We therefore hypothesized a
Externí odkaz:
https://doaj.org/article/9d05e3b0b880426b8a6d71870f8730c4
Autor:
Johannes Wach, Motaz Hamed, Tim Lampmann, Ági Güresir, Frederic Carsten Schmeel, Albert J. Becker, Ulrich Herrlinger, Hartmut Vatter, Erdem Güresir
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveMIB-1 index is an important predictor of meningioma progression. However, MIB-1 index is not available in the preoperative tailored medical decision-making process. A preoperative scoring sheet independently estimating MIB-1 indices in spina
Externí odkaz:
https://doaj.org/article/a470dceb5b334c809d53c754fe453cc3
Autor:
Niels Hansen, Guido Widman, Demet Önder, Kerstin Schwing, Pitshaporn Leelaarporn, Indra Prusseit, Randi von Wrede, Rainer Surges, Albert J. Becker, Juri-Alexander Witt, Christian E. Elger, Christoph Helmstaedter
Publikováno v:
Journal of Translational Autoimmunity, Vol 5, Iss , Pp 100167- (2022)
Background: Our goal is to investigate the autoantibodies’ presence and immune cells in the bioprobes of autoimmune encephalitis (AE) patients with distinct phenotypes as a promising target in AE. Methods: We retrospectively analyzed immune cells v
Externí odkaz:
https://doaj.org/article/d33506b91f094685a2bf1f758638c07d
Autor:
Despina Tsortouktzidis, Anna R. Tröscher, Herbert Schulz, Thoralf Opitz, Susanne Schoch, Albert J. Becker, Karen M. J. van Loo
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2022)
Precise genome editing in combination with viral delivery systems provides a valuable tool for neuroscience research. Traditionally, the role of genes in neuronal circuits has been addressed by overexpression or knock-out/knock-down systems. However,
Externí odkaz:
https://doaj.org/article/aaf2e69f713440a4b28de2318c21faa1
Autor:
Malin S Pohlentz, Philipp Müller, Silvia Cases-Cunillera, Thoralf Opitz, Rainer Surges, Motaz Hamed, Hartmut Vatter, Susanne Schoch, Albert J Becker, Julika Pitsch
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0271995 (2022)
ObjectiveInflammation of brain structures, in particular the hippocampal formation, can induce neuronal degeneration and be associated with increased excitability manifesting as propensity for repetitive seizures. An increase in the abundance of indi
Externí odkaz:
https://doaj.org/article/b473bab3c14b4299b4b666c55045f99f
Autor:
Attila Rácz, Albert J. Becker, Carlos M. Quesada, Valeri Borger, Hartmut Vatter, Rainer Surges, Christian E. Elger
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Purpose: Focal cortical dysplasias (FCDs) are a frequent cause of drug-resistant focal epilepsies. These lesions are in many cases amenable to epilepsy surgery. We examined 12-month and long-term post-surgical outcomes and its predictors including po
Externí odkaz:
https://doaj.org/article/da2cccfb32c94070948e3d17fe71179b
Autor:
Julia C Kuehn, Carolin Meschede, Christoph Helmstaedter, Rainer Surges, Randi von Wrede, Elke Hattingen, Hartmut Vatter, Christian E Elger, Susanne Schoch, Albert J Becker, Julika Pitsch
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241289 (2020)
Temporal lobe adult-onset seizures (TAOS) related to autoimmunity represent an increasingly recognized disease syndrome within the spectrum of epilepsies. In this context, certain autoantibodies (autoABs) were often associated with limbic encephaliti
Externí odkaz:
https://doaj.org/article/a283b3ab84954644b6368a14fe7f6bcb