Treatment outcome of atypical EGFR mutations in the German National Network Genomic Medicine Lung Cancer (nNGM)

Autor: Simon, Ronald, Sauter, Guido, Volk, Alexander, Neumann, Jens, Klauschen, Frederick, Weichert, Wilko, Kalhori, Naser, Lüthen, Reinhard, Stöhr, Robert, Schubart, Chistoph, Wacker, Heidemarie, Fuchs, Florian, Hartmann, Nils, Graf, Stefanie, Brandts, Christian, Wild, Peter, Demes, Melanie, Reis, Henning, Rohde, Gernot, Janning, M., Süptitz, J., Albers-Leischner, C., Delpy, P., Tufman, A., Velthaus-Rusik, J.-L., Reck, M., Jung, A., Kauffmann-Guerrero, D., Bonzheim, I., Brändlein, S., Hummel, H.-D., Wiesweg, M., Schildhaus, H.-U., Stratmann, J.A., Sebastian, M., Alt, J., Buth, J., Esposito, I., Berger, J., Tögel, L., Saalfeld, F.C., Wermke, M., Merkelbach-Bruse, S., Hillmer, A.M., Klauschen, F., Bokemeyer, C., Buettner, R., Wolf, J., Loges, S.

Publikováno v: In Annals of Oncology June 2022 33(6):602-615

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Mobocertinib in Patients with EGFR Exon 20 Insertion-Positive Non-Small Cell Lung Cancer (MOON): An International Real-World Safety and Efficacy Analysis.

Autor: Illini O; Department of Respiratory and Critical Care Medicine, Klinik Floridsdorf, Vienna Healthcare Group, Bruenner Straße 68, A-1210 Vienna, Austria.; Karl Landsteiner Institute of Lung Research and Pulmonary Oncology, A-1210 Vienna, Austria., Saalfeld FC; Clinic for Internal Medicine I, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases, 01307 Dresden, Germany.; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany., Christopoulos P; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Thoraxklinik and Translational Lung Research Center (TLRC), member of the German Center for Lung Research (DZL), Heidelberg University Hospital, 69126 Heidelberg, Germany., Duruisseaux M; Respiratory Department and Early Phase, Louis Pradel Hospital, Hospices Civils de Lyon Cancer Institute, 69002 Lyon, France.; Oncopharmacology Laboratory, Cancer Research Center of Lyon, Unité Mixte de Recherche (UMR), Institut National de la Santé et de la Recherche Médicale (INSERM), 1052 Centre National de la Recherche Scientifique (CNRS), 5286 Lyon, France.; Université Claude Bernard, Université de Lyon, 69622 Villeurbanne cedex, France., Vikström A; Department of Pulmonary Medicine, University Hospital Linköping, 58185 Linköping, Sweden., Peled N; The Hemsely Cancer Center, Shaare Zedek Medical Center, Jerusalem 9103102, Israel., Demedts I; Department of Pulmonary Diseases, AZ Delta, Deltalaan 1, 8800 Roeselare, Belgium., Dudnik E; Head, Thoracic Oncology Service, Assuta Medical Centers, Tel-Aviv 6329302, Israel.; Faculty of Health Sciences, Ben-Gurion Unversity of the Negev, Be'er Sheva 84105, Israel., Eisert A; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Lung Cancer Group Cologne, Department I for Internal Medicine and Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50937 Cologne, Germany., Hashemi SMS; Department of Pulmonary Medicine, Amsterdam UMC, VU University Medical Center, Cancer Center Amsterdam, 1081 Amsterdam, The Netherlands., Janzic U; Medical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.; Medical Oncology Unit, University Clinic Golnik, 4204 Golnik, Slovenia., Kian W; The Hemsely Cancer Center, Shaare Zedek Medical Center, Jerusalem 9103102, Israel.; Institute of Oncology, Assuta Ashdod University Hospital, Ashdod 7747629, Israel., Mohorcic K; Medical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia., Mohammed S; Kent Oncology Centre, Maidstone and Tunbridge Wells NHS Trust, Kent TN24QJ, UK., Silvoniemi M; Department of Pulmonary Diseases, Turku University Hospital, University of Turku, 20014 Turku, Finland., Rothschild SI; Center for Oncology & Hematology and Comprehensive Cancer Center, Cantonal Hospital Baden, 5404 Baden, Switzerland., Schulz C; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department of Internal Medicine II, University Hospital, 93053 Regensburg, Germany., Wesseler C; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department of Pneumology, Asklepios Tumorzentrum Hamburg, Klinikum Harburg, 21075 Hamburg, Germany., Addeo A; Oncology Department, University Hospital Geneva, 1205 Geneva, Switzerland., Armster K; Department of Pneumology, Universitätsklinikum Krems, 3500 Krems an der Donau, Austria., Itchins M; Department of Medical Oncology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.; Northern Clinical School, University of Sydney, St Leonards, NSW 2065, Australia., Ivanović M; Department of Oncology, University Medical Centre Maribor, 2000 Maribor, Slovenia., Kauffmann-Guerrero D; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Division of Respiratory Medicine and Thoracic Oncology, Department of Medicine V, Thoracic Oncology Center Munich, University Hospital, University of Munich (LMU), 81377 Munich, Germany., Koivunen J; Department of Oncology and Radiotherapy, Oulu University Hospital, 90014 Oulu, Finland.; Cancer and Translational Medicine Research Unit, University of Oulu, 90014 Oulu, Finland.; Medical Research Center Oulu, 90014 Oulu, Finland., Kuon J; Department Thoracic Oncology, SLK Fachklinik Löwenstein, 74245 Löwenstein, Germany., Pavlakis N; Department of Medical Oncology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia.; Northern Clinical School, University of Sydney, St Leonards, NSW 2065, Australia., Piet B; Department of Respiratory Medicine, Radboudumc, 6225 GA Nijmegen, The Netherlands., Sebastian M; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department of Medicine, Hematology/Oncology, University Hospital, University of Frankfurt, 60596 Frankfurt am Main, Germany., Velthaus-Rusik JL; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Comprehensive Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany., Wannesson L; Istituto Oncologico della Svizzera Italiana, 6500 Bellinzona, Switzerland., Wiesweg M; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; West German Cancer Center, Department of Medical Oncology, University Duisburg-Essen, 45147 Essen, Germany., Wurm R; Division of Pulmonology, Department of Internal Medicine, LKH-Universitätsklinikum, Medical University of Graz, 8036 Graz, Austria., Albers-Leischner C; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Comprehensive Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany., Aust DE; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department for Pathology, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany., Janning M; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; DKFZ-Hector Cancer Institute at the University Medical Center Mannheim, 68167 Mannheim, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; German Center for Lung Research (DZL), 69120 Heidelberg, Germany., Fabikan H; Karl Landsteiner Institute of Lung Research and Pulmonary Oncology, A-1210 Vienna, Austria., Herold S; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department for Pathology, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany., Klimova A; Core Unit for Data Management and Analytics, National Center for Tumor Diseases, 01307 Dresden, Germany., Loges S; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; DKFZ-Hector Cancer Institute at the University Medical Center Mannheim, 68167 Mannheim, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; German Center for Lung Research (DZL), 69120 Heidelberg, Germany., Sharapova Y; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; DKFZ-Hector Cancer Institute at the University Medical Center Mannheim, 68167 Mannheim, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; German Center for Lung Research (DZL), 69120 Heidelberg, Germany., Schütz M; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department for Pathology, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany., Weinlinger C; Karl Landsteiner Institute of Lung Research and Pulmonary Oncology, A-1210 Vienna, Austria., Valipour A; Department of Respiratory and Critical Care Medicine, Klinik Floridsdorf, Vienna Healthcare Group, Bruenner Straße 68, A-1210 Vienna, Austria.; Karl Landsteiner Institute of Lung Research and Pulmonary Oncology, A-1210 Vienna, Austria., Overbeck TR; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department of Hematology and Medical Oncology, University Medical Center Göttingen, Göttingen University, 37075 Göttingen, Germany., Griesinger F; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.; Department of Hematology and Oncology, Pius University Hospital, University Medicine Oldenburg, 26121 Oldenburg, Germany., Jakopovic M; Department for Respiratory Diseases Jordanovac, University Hospital Center Zagreb, 10000 Zagreb, Croatia.; School of Medicine, University of Zagreb, 10000 Zagreb, Croatia., Hochmair MJ; Department of Respiratory and Critical Care Medicine, Klinik Floridsdorf, Vienna Healthcare Group, Bruenner Straße 68, A-1210 Vienna, Austria.; Karl Landsteiner Institute of Lung Research and Pulmonary Oncology, A-1210 Vienna, Austria., Wermke M; Clinic for Internal Medicine I, University Hospital Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany.; National Center for Tumor Diseases, 01307 Dresden, Germany.; National Network Genomic Medicine Lung Cancer (nNGM), 50937 Cologne, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 03; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 03.