Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Albee, Messing"'
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/c8a7bb495d784a699e22801c2b343fb6
Autor:
Michelle M. Boyd, Suzanne J. Litscher, Laura L. Seitz, Albee Messing, Tracy L. Hagemann, Lara S. Collier
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background Alexander disease (AxD) is a rare neurodegenerative disorder that is caused by dominant mutations in the gene encoding glial fibrillary acidic protein (GFAP), an intermediate filament that is primarily expressed by astrocytes. In
Externí odkaz:
https://doaj.org/article/1f287bbee59c40abaa415f56c48a0634
Publikováno v:
Cells, Vol 12, Iss 7, p 978 (2023)
Alexander disease (AxD) is caused by mutations in the gene for glial fibrillary acidic protein (GFAP), an intermediate filament expressed by astrocytes in the central nervous system. AxD-associated mutations cause GFAP aggregation and astrogliosis, a
Externí odkaz:
https://doaj.org/article/73cf2e06e61d4e96bc33ab64935f77de
Autor:
Albee Messing
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 11, Iss 1, Pp 1-4 (2019)
Abstract Background Alexander disease is caused by dominantly acting mutations in glial fibrillary acidic protein (GFAP), the major intermediate filament of astrocytes in the central nervous system. Main body In addition to the sequence variants that
Externí odkaz:
https://doaj.org/article/63ab39b70d614bd985004e5d90724aa3
Autor:
Michael Brenner, Albee Messing
Publikováno v:
ASN Neuro, Vol 13 (2021)
Expression of the GFAP gene has attracted considerable attention because its onset is a marker for astrocyte development, its upregulation is a marker for reactive gliosis, and its predominance in astrocytes provides a tool for their genetic manipula
Externí odkaz:
https://doaj.org/article/8519bc11f91b450797ecc740ec7d3f04
Publikováno v:
Journal of the History of the Neurosciences. :1-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::187f2db0d4111e8a043e65e825ebde99
https://doi.org/10.1080/0964704x.2023.2190354
https://doi.org/10.1080/0964704x.2023.2190354
Autor:
Albee Messing, Michael Brenner
Publikováno v:
ASN Neuro, Vol 12 (2020)
Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament family of proteins, it has become a subject for study in fields as diverse a
Externí odkaz:
https://doaj.org/article/713dc578fb2b42eab692e802b2a95867
Autor:
Liqun Wang, Jing Xia, Jonathan Li, Tracy L. Hagemann, Jeffrey R. Jones, Ernest Fraenkel, David A. Weitz, Su-Chun Zhang, Albee Messing, Mel B. Feany
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Alexander disease is a rare neurodegeneration caused by mutations in a glial gene GFAP. Here, Wang and colleagues show in animal models of Alexander disease that GFAP mutant brain and cells have greater tissue and cellular stiffness and greater activ
Externí odkaz:
https://doaj.org/article/36c12df858ac434183e838e24dc960c5
Autor:
Liqun Wang, Hassan Bukhari, Linghai Kong, Tracy L. Hagemann, Su-Chun Zhang, Albee Messing, Mel B. Feany
Publikováno v:
J Neurosci
Anastasis is a recently described process in which cells recover after late-stage apoptosis activation. The functional consequences of anastasis for cells and tissues are not clearly understood. UsingDrosophila, rat and human cells and tissues, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006458fbdb887a687f4839167f5fbcff
https://doi.org/10.1523/jneurosci.1659-21.2021
https://doi.org/10.1523/jneurosci.1659-21.2021
Autor:
Jeffrey R. Jones, Linghai Kong, Michael G. Hanna, IV, Brianna Hoffman, Robert Krencik, Robert Bradley, Tracy Hagemann, Jeea Choi, Matthew Doers, Marina Dubovis, Mohammad Amin Sherafat, Anita Bhattacharyya, Christina Kendziorski, Anjon Audhya, Albee Messing, Su-Chun Zhang
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 947-958.e4 (2018)
Summary: How mutations in glial fibrillary acidic protein (GFAP) cause Alexander disease (AxD) remains elusive. We generated iPSCs from two AxD patients and corrected the GFAP mutations to examine the effects of mutant GFAP on human astrocytes. AxD a
Externí odkaz:
https://doaj.org/article/8661b3e265394aa380281091f516e8d2