Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Albebson L. Lim"'
Autor:
Albebson L. Lim, Bailey W. Miller, Zhenjian Lin, Mark A. Fisher, Louis R. Barrows, Margo G. Haygood, Eric W. Schmidt
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Turnercyclamycin A and B lipopeptides exhibit Gram-negative bacteria-specific toxicity. This includes CDC urgent threat organisms such as multidrug-resistant Acinetobacter baumannii. Like the last-line agent colistin, turnercyclamycins inter
Externí odkaz:
https://doaj.org/article/54c4046ef672420ebbd5753d2a69f3bd
Autor:
Albebson L. Lim, Philip Moos, Christopher D. Pond, Erica C. Larson, Laura J. Martins, Matthew A. Szaniawski, Vicente Planelles, Louis R. Barrows
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 386-413 (2022)
HIV-1 cDNA pre-integration complexes persist for weeks in macrophages and remain transcriptionally active. While previous work has focused on the transcription of HIV-1 genes; our understanding of the cellular milieu that accompanies viral production
Externí odkaz:
https://doaj.org/article/d117a10300674c17bc372d36e1db60f3
Autor:
Cheryl Dowell, Zhenjian Lin, Baldomero M. Olivera, Ronald W. Hughen, Randall T. Peterson, Albebson L. Lim, Jie Zhang, Kevin Chase, J. Michael McIntosh, Noemi D. Paguigan, Lee S. Leavitt, Eric W. Schmidt, Shrinivasan Raghuraman, Manju Karthikeyan, Christopher A. Reilly, Cassandra E. Deering-Rice, Jortan O. Tun, Alan R. Light
Publikováno v:
ACS Chem Neurosci
In our efforts to discover new drugs to treat pain, we identified molleamines A-E (1-5) as major neuroactive components of the sea slug, Pleurobranchus forskalii, and their prey, Didemnum molle, tunicates. The chemical structures of molleamines were
Drug-resistant Acinetobacter is a challenging, deadly pathogen of increasing prevalence in the US healthcare system. Recently, we described a series of lipopeptides, the turnercyclamycins, which retain potency against Acinetobacter strains that are r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301d00a1fcba501e737641e903a48792
https://doi.org/10.1101/2021.11.01.466777
https://doi.org/10.1101/2021.11.01.466777
Autor:
Eric W. Schmidt, Albebson L. Lim, Kari L. Aoyagi, Colin Manoil, Jeannie F. Bailey, Mark A. Fisher, Zhenjian Lin, Louis R. Barrows, Margo G. Haygood, Bailey W. Miller
Publikováno v:
Cell Chem Biol
Summary Teredinibacter turnerae is an intracellular bacterial symbiont in the gills of wood-eating shipworms, where it is proposed to use antibiotics to defend itself and its animal host. Several biosynthetic gene clusters are conserved in T. turnera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4d19ff56dc9f5893cccf01e9199f63
https://europepmc.org/articles/PMC8605984/
https://europepmc.org/articles/PMC8605984/
Autor:
Manju Karthikeyan, Jortan O. Tun, Kevin Chase, Lee S. Leavitt, Albebson L. Lim, Shrinivasan Raghuraman, Cheryl Dowell, Ronald W. Hughen, Alan R. Light, Baldomero M. Olivera, J. M. McIntosh, Jie Zhang, Noemi D. Paguigan, Eric W. Schmidt, Christopher A. Reilly, Zhenjian Lin, Cassandra E. Deering-Rice, Randall T. Peterson
In our efforts to discover new drugs to treat pain, we identified molleamines A-E (1-5) as major neuroactive components of the sea slug, Pleurobranchus forskalii and their prey, Didemnum molle tunicates. The chemical structures of molleamines were el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a93867834e3506529c91e592477639ba
https://doi.org/10.1101/2021.05.17.444536
https://doi.org/10.1101/2021.05.17.444536
Autor:
Albebson L. Lim, Christopher D. Pond, Laura J. Martins, Planelles, Erica C. Larson, Philip J. Moos, Louis R. Barrows, Matthew A. Szaniawski
HIV-1 cDNA pre-integration complexes have been shown to persist for weeks in macrophages and to be transcriptionally active. Early and late gene transcripts are produced, along with some viral proteins, yet whole virus is not. While previous work has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::423e2bbe01f812074460f679a7a06482
https://doi.org/10.1101/2021.04.21.440655
https://doi.org/10.1101/2021.04.21.440655
Autor:
Tosifa A. Memon, Nicole Schmitt, Jackson Carter, Kevin Chase, Noemi D. Paguigan, Yannan Yan, Shrinivasan Raghuraman, Zhenjian Lin, Eric W. Schmidt, Albebson L. Lim, Christopher A. Reilly, Bo Hjorth Bentzen, Russell W. Teichert, Manju Karthikeyan, Baldomero M. Olivera, Lee S. Leavitt, Sean Christensen
Publikováno v:
Paguigan, N D, Yan, Y, Karthikeyan, M, Chase, K, Carter, J, Leavitt, L S, Lim, A L, Lin, Z, Memon, T, Christensen, S, Bentzen, B H, Schmitt, N, Reilly, C A, Teichert, R W, Raghuraman, S, Olivera, B M & Schmidt, E W 2021, ' The Tunicate Metabolite 2-(3,5-Diiodo-4-methoxyphenyl)ethan-1-amine Targets Ion Channels of Vertebrate Sensory Neurons ', ACS chemical biology, vol. 16, no. 9, pp. 1654-1662 . https://doi.org/10.1021/acschembio.1c00328
Marine tunicates produce defensive amino-acid derived metabolites, including 2-(3,5-diiodo-4-methoxyphenyl)ethan-1-amine (DIMTA), but their mechanisms of action are rarely known. Using an assay-guided approach, we found that out of the many different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9884ca44604783f84921e5567db85434
https://curis.ku.dk/ws/files/285240582/The_tunicate_metabolite_2_3_5_diiodo_4_methoxyphenyl_ethan_1_.pdf
https://curis.ku.dk/ws/files/285240582/The_tunicate_metabolite_2_3_5_diiodo_4_methoxyphenyl_ethan_1_.pdf
Autor:
Bailey W. Miller, Albebson L. Lim, Zhenjian Lin, Jeannie Bailey, Louis R. Barrows, Colin Manoil, Eric W. Schmidt, Margo G. Haygood
Teredinibacter turnerae is an intracellular bacterial symbiont that lives in the gills of wood-eating shipworms, where it is proposed to use antibiotics to defend itself and its animal host. Several biosynthetic gene clusters are conserved in T. turn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab1951e4a5d7cbaaccdb9328dcd2b22
https://doi.org/10.26434/chemrxiv.13215578
https://doi.org/10.26434/chemrxiv.13215578
Autor:
Christopher D. Pond, Erica C. Larson, Albebson L. Lim, Grover L. Waldrop, Matthew Craft, Mirela Čavužić, Louis R. Barrows, Eric W. Schmidt
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233485 (2020)
PLoS ONE
PLoS ONE
Antimicrobial resistance is a growing global health and economic concern. Current antimicrobial agents are becoming less effective against common bacterial infections. We previously identified pyrrolocins A and C, which showed activity against a vari