Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Albana Gattelli"'
Autor:
Sabrina A. Vallone, Martín García Solá, Carolina Schere-Levy, Roberto P. Meiss, Gladys N. Hermida, Lewis A. Chodosh, Edith C. Kordon, Nancy E. Hynes, Albana Gattelli
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 3 (2022)
RET is a receptor tyrosine kinase with oncogenic potential in the mammary epithelium. Several receptors with oncogenic activity in the breast are known to participate in specific developmental stages. We found that RET is differentially expressed dur
Externí odkaz:
https://doaj.org/article/f52ccb7806184957a96b202402aab883
Autor:
Carolina Schere-Levy, Melisa Suberbordes, Darío M. Ferri, Marina Ayre, Albana Gattelli, Edith C. Kordon, Ana R. Raimondi, Thomas Walther
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3642 (2022)
Oral Squamous Cell Carcinoma (OSCC) is the most common malignant cancer affecting the oral cavity. It is characterized by high morbidity and very few therapeutic options. Angiotensin (Ang)-(1-7) is a biologically active heptapeptide, generated predom
Externí odkaz:
https://doaj.org/article/a6a11743dc5c44c18c1b116deac3fc70
Autor:
Alessia Bottos, Dagmar Gotthardt, Jason W. Gill, Albana Gattelli, Anna Frei, Alexandar Tzankov, Veronika Sexl, Aleksandra Wodnar-Filipowicz, Nancy E. Hynes
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
JAK inhibitors are currently undergoing evaluation in clinical trials for advanced breast cancer. Here, the authors show that JAK pathway inhibition increases metastasis in mouse models of breast cancer by impairing NK anti-tumour activity and that t
Externí odkaz:
https://doaj.org/article/86420aae63434acfa4d1039c29037e97
Autor:
Nancy E. Hynes, Edith C. Kordon, Albana Gattelli, Robert D. Cardiff, Martín E. García Solá, Lewis A. Chodosh, Tim Roloff
Publikováno v:
Oncogene. 37:4046-4054
The receptor tyrosine kinase Ret, a key gain-of-function mutated oncoprotein in thyroid carcinomas, has recently been implicated in other cancer types. While Ret copy number gains and mutations have been reported at low frequencies in breast tumors,
Autor:
Deborah J. Stumpo, Micaela Stedile, Nancy E. Hynes, Albana Gattelli, Edith C. Kordon, Roberto Meiss, Lourdes Pérez Cuervo, María Victoria Goddio, Johanna M. Tocci, Perry J. Blackshear
Publikováno v:
Oncotarget
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Tristetraprolin (TTP), an mRNA-binding protein that negatively controls levels of inflammatory factors, is highly expressed in the lactating mouse mammary gland. To determine the biological relevance of this expression profile, we developed bi-transg
Autor:
Nancy E. Hynes, Lewis A. Chodosh, Edith C. Kordon, Robert D. Cardiff, Roberto Meiss, Carolina Shere-Levy, Albana Gattelli, Sabrina A. Vallone, Martín E García Solá
Publikováno v:
Cancer Research. 80:3685-3685
Loss of normal development is a hallmark of cancer. Thus, understanding the mechanisms of tissue-specific developmental regulation and the changes that occur during tumorigenesis may provide insights of both diagnostic and therapeutic importance. In
Publikováno v:
Cancer Research. 72:PD01-06
The Ret receptor tyrosine kinase is overexpressed in approximately 30% of human breast cancers, many of which are estrogen receptor-alpha positive (ER+). Using the ER+ breast cancer models MCF7 and T47D, we have shown that RET is an ER target gene an
Autor:
Dagmar Gotthardt, Alessia Bottos, Aleksandra Wodnar-Filipowicz, Jason Gill, Alexandar Tzankov, Albana Gattelli, Veronika Sexl, Anna Frei, Nancy E. Hynes
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The JAK/STAT pathway is an attractive target for breast cancer therapy due to its frequent activation, and clinical trials evaluating JAK inhibitors (JAKi) in advanced breast cancer are ongoing. Using patient biopsies and preclinical models of breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42511f44d7b530daee9274df8b59a02
https://www.nature.com/articles/ncomms12258
https://www.nature.com/articles/ncomms12258
Autor:
Matías Blaustein, Carolina Schere Levy, Omar A. Coso, Victoria Slomiansky, Albana Gattelli, Federico Pelisch, Edith C. Kordon, Karen Nahmod, Anabella Srebrow
Publikováno v:
Journal of Cellular Biochemistry. 110:857-865
It has been reported that expression of tumor necrosis factor superfamily members occur at the onset of the mammary gland post-lactational involution. One of these proteins, tumor necrosis factor alpha (TNFalpha), is a major mediator of inflammation
Autor:
Lucio H. Castilla, Carolina Schere-Levy, Albana Gattelli, María Julieta Binaghi, Roberto Meiss, Ana Quaglino, María Cecilia Cirio, Edith C. Kordon, Natalia J. Martinez
Publikováno v:
Cancer Research. 64:5193-5199
Mouse mammary tumor virus (LA) induces pregnancy-dependent mammary tumors that progress toward autonomy. Here we show that in virgin females, pregnancy-dependent tumor transplants are able to remain dormant for up to 300 days. During that period, the