Výsledky vyhledávání - "Albana Cumashi"

Akademický článek

Fucans, but not fucomannoglucuronans, determine the biological activities of sulfated polysaccharides from Laminaria saccharina brown seaweed.

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e17283 (2011)

Sulfated polysaccharides from Laminaria saccharina (new name: Saccharina latissima) brown seaweed show promising activity for the treatment of inflammation, thrombosis, and cancer; yet the molecular mechanisms underlying these properties remain poorl

Externí odkaz: https://doaj.org/article/81db8383eece4973aaf03285706bf918

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LGALS3BP, lectin galactoside-binding soluble 3 binding protein, induces vascular endothelial growth factor in human breast cancer cells and promotes angiogenesis

Autor: Annalisa Di Risio, Axel Ullrich, Rossano Lattanzio, Enza Piccolo, Nicola Tinari, Albana Cumashi, Clara Natoli, Francesca Spinella, Sara Traini, Rossana La Sorda, Imma Fichera, Mauro Piantelli, Anna Bagnato, Pavlos Stampolidis, Stefano Iacobelli, Daniela Semeraro, Maurizia D'Egidio

Publikováno v: Journal of Molecular Medicine. 91:83-94

Elevated serum or tissue levels of lectin galactoside-binding soluble 3 binding protein (LGALS3BP) have been associated with short survival and development of metastasis in a variety of human cancers. However, the role of LGALS3BP, particularly in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3a7b3abcbcf6eefcb3b73e5523d097
https://doi.org/10.1007/s00109-012-0936-6

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P53 mutations in colorectal cancer from northern Iran: Relationships with site of tumor origin, microsatellite instability and K-ras mutations

Autor: Mauro Piantelli, Stefano Iacobelli, Mahshid Hormazdi, Renato Mariani-Costantini, Faraz Bishehsari, Reza Malekzadeh, Maria Cristina Curia, Reza Ansari, Alessandro Cama, Naser Rakhshani, Rossano Lattanzio, Hafez Fakheri, Mahboobeh Mahdavinia, Daniela Semeraro, Fabio Verginelli, Masoud Sotoudeh, Laura De Lellis, Albana Cumashi

Publikováno v: Journal of Cellular Physiology. 216:543-550

CRC-associated P53 mutations have not been studied extensively in non-Western countries at relatively low CRC risk. We examined, for the first time, 196 paraffin-embedded CRC cases from Northern Iran for mutations in P53 exons 5-8 using PCR-direct se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fdadf389d6976e2c0919d7a3aaaa04
https://doi.org/10.1002/jcp.21428

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Interactions of Mast Cell Tryptase with Thrombin Receptors and PAR-2

Autor: Albana Cumashi, Robert Numerof, Marina Molino, Mark Dreyer, Norman Schechter, James A. Hoxie, James D. Clark, Elliot S. Barnathan, Marilyn J. Woolkalis, Lawrence F. Brass

Publikováno v: Journal of Biological Chemistry. 272:4043-4049

Tryptase is a serine protease secreted by mast cells that is able to activate other cells. In the present studies we have tested whether these responses could be mediated by thrombin receptors or PAR-2, two G-protein-coupled receptors that are activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1635baf6da9556386cff5f4cc41f08
https://doi.org/10.1074/jbc.272.7.4043

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Sunitinib malate (SU-11248) alone or in combination with low-dose docetaxel inhibits the growth of DU-145 prostate cancer xenografts

Autor: Clara Natoli, Albana Cumashi, Rossano Lattanzio, Nicola Tinari, Stefano Iacobelli, Mauro Piantelli, Cosmo Rossi

Publikováno v: Cancer letters. 270(2)

The aim of the study was to evaluate the activity of the antiangiogenic agent SU-11248 (sunitinib malate, Sutent®), alone or in combination with docetaxel. To this end, animals bearing DU-145 human hormone-refractory prostate cancer (HRPC) xenograft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ba974d2ba0bd710f910a6828948639
https://pubmed.ncbi.nlm.nih.gov/18586384

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A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds

Autor: Licia Totani, M. E. Preobrazhenskaya, Anatolii I. Usov, Antonio Piccoli, Armida D'Incecco, Maeve Kelly, Nikolay E. Nifantiev, Galina E. Morozevich, Maria I. Bilan, Nicola Tinari, N. A. Ushakova, Alexey A. Grachev, Stefano Iacobelli, Albana Cumashi, Nadezhda E. Ustyuzhanina, A. E. Berman, Gabriel A. Rabinovich, Craig J. Sanderson

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The anti-inflammatory, antiangiogenic, anticoagulant, and antiadhesive properties of fucoidans obtained from nine species of brown algae were studied in order to examine the influence of fucoidan origin and composition on their biological activities.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c88ae6aa01f3afc1598b506086dd846
https://academic.oup.com/glycob/article-lookup/doi/10.1093/glycob/cwm014

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Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis

Autor: Domenico Ciavardelli, Gabriel A. Rabinovich, Albana Cumashi, Ida Iurisci, Enza Piccolo, Nikolay E. Nifantiev, Nicola Tinari, Maurizia D'Egidio, Germán A Bianco, Stefano Iacobelli

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Galectins, a family of structurally related carbohydrate-binding proteins, contribute to different events associated with cancer biology, including apoptosis, homotypic cell aggregation, angiogenesis and tumor-immune escape. To interfere with galecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf01acd031d7d42c7160ff998aa1cff
https://academic.oup.com/glycob/article/16/3/210/716073

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Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects

Autor: Albana Cumashi, Manuela Iezzi, Paolo Innocenti, Enza Piccolo, Adolfo Saiardi, Massimo Broggini, Barry V. L. Potter, Andrew M. Riley, Stefano Iacobelli, Marco Falasca, Cosmo Rossi, Tania Maffucci, H. Yasmin Godage

Publikováno v: Cancer research. 65(18)

The purpose of this study was to investigate the antiangiogenic and in vivo properties of the recently identified phosphatidylinositol 3-kinase (PI3K)/Akt inhibitor Inositol(1,3,4,5,6) pentakisphosphate [Ins(1,3,4,5,6)P5]. Because activation of the P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a094c9f824dd6e24b419358b2b626d
https://pubmed.ncbi.nlm.nih.gov/16166311

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Neutrophil proteases can inactivate human PAR3 and abolish the co-receptor function of PAR3 on murine platelets

Autor: Albana Cumashi, Antonio De Blasi, Marina Molino, Nicola Celli, Helenia Ansuini, Lawrence F. Brass, Peter J. O'Brien

SummaryThree members of the protease-activated receptor family, PAR1, PAR3 and PAR4, are activated when thrombin cleaves the receptor N-terminus, exposing a tethered ligand. Proteases other than thrombin can also cleave PAR family members and, depend

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b546d1bae72e6844e079a62cc3dcc39
http://hdl.handle.net/11573/452763

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