Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Alban, Longchamp"'
Autor:
Ozge Sila Ozgur, Mclean Taggart, Mohammedreza Mojoudi, Casie Pendexter, Irina Filz von Reiterdank, Anil Kharga, Heidi Yeh, Mehmet Toner, Alban Longchamp, Shannon N. Tessier, Korkut Uygun
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Preserving organs at subzero temperatures with halted metabolic activity holds the potential to prolong preservation and expand the donor organ pool for transplant. Our group recently introduced partial freezing, a novel approach in high-sub
Externí odkaz:
https://doaj.org/article/0a44f97abddf4e259e421489770299b9
Autor:
Thomas Agius, Raffaella Emsley, Arnaud Lyon, Michael R. MacArthur, Kevin Kiesworo, Anna Faivre, Louis Stavart, Martine Lambelet, David Legouis, Sophie de Seigneux, Déla Golshayan, Francois Lazeyras, Heidi Yeh, James F. Markmann, Korkut Uygun, Alejandro Ocampo, Sarah J. Mitchell, Florent Allagnat, Sébastien Déglise, Alban Longchamp
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Dietary restriction promotes resistance to surgical stress in multiple organisms. Counterintuitively, current medical protocols recommend short-term carbohydrate-rich drinks (carbohydrate loading) prior to surgery, part of a multimodal perio
Externí odkaz:
https://doaj.org/article/ffeaabec74c8436cb692b16a68581716
Autor:
Salomé Kuntz, Céline Deslarzes, Alexandre Than Vinh Nguyen, Alban Longchamp, Rosalinda D'Amico, Justine Longchamp, Anne Lejay, Nabil Chakfé, Sébastien Déglise
Publikováno v:
EJVES Vascular Forum, Vol 62, Iss , Pp 8-14 (2024)
Introduction: Endovascular aneurysm sealing (EVAS) appeared to be an innovative alternative to conventional endovascular abdominal aortic aneurysm repair. However, high rates of midterm failure of EVAS led to withdrawal of the device from the market.
Externí odkaz:
https://doaj.org/article/d957b2ce93f0422f83876a267e77ecf0
Autor:
Alban Longchamp, MD, PhD, Fermin M. Fontan, MD, Mohamed M. Aburawi, MD, Corey Eymard, MD, Negin Karimian, MD, PhD, Danielle Detelich, MD, Casie Pendexter, BS, Stephanie Cronin, MS, Thomas Agius, MS, Sonal Nagpal, MBA, Peony Dutta Banik, BS, Shannon N. Tessier, PhD, Sinan Ozer, MBA, Francis L. Delmonico, MD, Korkut Uygun, PhD, Heidi Yeh, MD, James F. Markmann, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 4, p e1609 (2024)
Background. Brief normothermic machine perfusion is increasingly used to assess and recondition grafts before transplant. During normothermic machine perfusion, metabolic activity is typically maintained using red blood cell (RBC)–based solutions.
Externí odkaz:
https://doaj.org/article/396aa870c24442cab2483459c99fec7e
Autor:
Thomas Agius, MS, Julien Songeon, MS, Arnaud Lyon, MD, Justine Longchamp, MD, Raphael Ruttimann, BS, Florent Allagnat, PhD, Sébastien Déglise, MD, Jean-Marc Corpataux, MD, Déla Golshayan, MD, PhD, Léo Buhler, MD, Raphael Meier, MD, PhD, Heidi Yeh, MD, James F. Markmann, MD, PhD, Korkut Uygun, PhD, Christian Toso, MD, PhD, Antoine Klauser, PhD, Francois Lazeyras, PhD, Alban Longchamp, MD, PhD
Publikováno v:
Transplantation Direct, Vol 9, Iss 11, p e1508 (2023)
Background. In rodents, hydrogen sulfide (H2S) reduces ischemia-reperfusion injury and improves renal graft function after transplantation. Here, we hypothesized that the benefits of H2S are conserved in pigs, a more clinically relevant model. Method
Externí odkaz:
https://doaj.org/article/62a376d8015c4df09588e2f10fda8ffe
Autor:
Yanis Berkane, Justine Hayau, Irina Filz von Reiterdank, Anil Kharga, Laura Charlès, Abele B. Mink van der Molen, J. Henk Coert, Nicolas Bertheuil, Mark A. Randolph, Curtis L. Cetrulo, Alban Longchamp, Alexandre G. Lellouch, Korkut Uygun
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
Ex vivo preservation of transplanted organs is undergoing spectacular advances. Machine perfusion is now used in common practice for abdominal and thoracic organ transportation and preservation, and early results are in favor of substantially improve
Externí odkaz:
https://doaj.org/article/cc3af59de2134081ba834eaf550c4f04
Autor:
Cyril Statzer, Jin Meng, Richard Venz, Monet Bland, Stacey Robida-Stubbs, Krina Patel, Dunja Petrovic, Raffaella Emsley, Pengpeng Liu, Ianessa Morantte, Cole Haynes, William B. Mair, Alban Longchamp, Milos R. Filipovic, T. Keith Blackwell, Collin Y. Ewald
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The authors showed that, in C. elegans, inhibition of translation or mTORC1 increases ATF-4 expression independently of ISR signalling. ATF-4 promotes longevity by increasing hydrogen sulfide production by the enzyme CTH-2.
Externí odkaz:
https://doaj.org/article/0b2d369bb38048e0accd70b4ceb4ae16
Autor:
Kevin Kiesworo, MS, Michael R. MacArthur, PhD, Peter Kip, MD, PhD, Thomas Agius, MS, Diane Macabrey, MS, Martine Lambelet, BS, Lauriane Hamard, PhD, C.-Keith Ozaki, MD, James R. Mitchell, PhD, Sébastien Déglise, MD, Sarah J. Mitchell, PhD, Florent Allagnat, PhD, Alban Longchamp, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100095- (2023)
Objective: Hydrogen sulfide is a proangiogenic gas produced primarily by the transsulfuration enzyme cystathionine-γ-lyase (CGL). CGL-dependent hydrogen sulfide production is required for neovascularization in models of peripheral arterial disease.
Externí odkaz:
https://doaj.org/article/b42f3d703389433f826588a2962e476a
Autor:
Thomas Agius, MS, Julien Songeon, MS, Antoine Klauser, PhD, Florent Allagnat, PhD, Grégoire Longchamp, MD, Raphael Ruttimann, BS, Arnaud Lyon, MD, Julijana Ivaniesevic, PhD, Raphael Meier, MD, PhD, Sébastien Déglise, MD, James F. Markmann, MD, PhD, Korkut Uygun, PhD, Leo Buhler, MD, Christian Toso, MD, PhD, Jean-Marc Corpataux, MD, Francois Lazeyras, PhD, Alban Longchamp, MD, PhD
Publikováno v:
Transplantation Direct, Vol 8, Iss 10, p e1354 (2022)
Background. The ideal preservation temperature for donation after circulatory death kidney grafts is unknown. We investigated whether subnormothermic (22 °C) ex vivo kidney machine perfusion could improve kidney metabolism and reduce ischemia-reperf
Externí odkaz:
https://doaj.org/article/9276f252910e4f959f46c683d1fc53c6
Autor:
Diane Macabrey, Jaroslava Joniová, Quentin Gasser, Clémence Bechelli, Alban Longchamp, Severine Urfer, Martine Lambelet, Chun-Yu Fu, Guenter Schwarz, Georges Wagnières, Sébastien Déglise, Florent Allagnat
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Therapies to accelerate vascular repair are currently lacking. Pre-clinical studies suggest that hydrogen sulfide (H2S), an endogenous gasotransmitter, promotes angiogenesis. Here, we hypothesized that sodium thiosulfate (STS), a clinically relevant
Externí odkaz:
https://doaj.org/article/b67cad54c98c42b880d158e82afd8e42