Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Alban, Girault"'
Autor:
Mélissa Aubin Vega, Alban Girault, Émilie Meunier, Jasmine Chebli, Anik Privé, Annette Robichaud, Damien Adam, Emmanuelle Brochiero
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Acute respiratory distress syndrome (ARDS) is characterized by an exacerbated inflammatory response, severe damage to the alveolar-capillary barrier and a secondary infiltration of protein-rich fluid into the airspaces, ultimately leading to respirat
Externí odkaz:
https://doaj.org/article/4b228a77fedb46b29c61d583e81c66ea
Autor:
Mélissa Aubin Vega, Alban Girault, Damien Adam, Jasmine Chebli, Anik Privé, Émilie Maillé, Annette Robichaud, Emmanuelle Brochiero
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Alveolar ion and fluid absorption is essential for lung homeostasis in healthy conditions as well as for the resorption of lung edema, a key feature of acute respiratory distress syndrome. Liquid absorption is driven by active transepithelial sodium
Externí odkaz:
https://doaj.org/article/6aacdb21c09e4a729b3a925b1fee8a25
Autor:
Emilie Lereclus, Mira Tout, Alban Girault, Nadine Baroukh, Morgane Caulet, Christophe Borg, Olivier Bouché, David Ternant, Gilles Paintaud, Thierry Lecomte, William Raoul
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Colorectal cancer is a major public health issue worldwide. Interleukin-17 (IL-17) and Th17 (T-helper cell type 17)-related molecules are involved in tumor development and in resistance to bevacizumab, an anti-vascular endothelial
Externí odkaz:
https://doaj.org/article/a8c37056c41044d689e6b839974df1b8
Autor:
Christophe Vandier, Philippe Bougnoux, Virginie Joulin, Pierre Besson, Michelle Pinault, Paul-Alain Jaffrès, Jean-Pierre Haelters, Flavie Arbion, Alban Girault, Thibauld Oullier, Christine Collin, Jean-Christophe Pagès, Maxime Guéguinou, Séverine Marionneau-Lambot, Gaëlle Fromont, Lucie Clarysse, Marie Potier-Cartereau, Aurélie Chantôme
PDF file - 579K, S1. Validation of the MDA-MB-435s cell system expressing luciferase gene and expressing or not KCNN3 gene. S2. SK3 knockdown reduced the development of metastases in cancer cell xenograft models. A) SK3 knockdown reduced the metastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d555adbcffe04e87d3b59d34a2c8cc68
https://doi.org/10.1158/0008-5472.22396100.v1
https://doi.org/10.1158/0008-5472.22396100.v1
Autor:
Julie, Schnipper, Sana, Kouba, Frédéric, Hague, Alban, Girault, Marie-Sophie, Telliez, Stéphanie, Guénin, Ahmed, Ahidouch, Stine Falsig, Pedersen, Halima, Ouadid-Ahidouch
Publikováno v:
Cancers. 14(19)
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with a low overall survival rate of less than 10% and limited therapeutic options. Fluctuations in tumor microenvironment pH are a hallmark of PDAC development and p
Autor:
Julie Schnipper, Sana Kouba, Frédéric Hague, Alban Girault, Pierre Rybarczyk, Marie-Sophie Telliez, Stéphanie Guénin, Riad Tebbakha, Henri Sevestre, Ahmed Ahidouch, Stine Falsig Pedersen, Halima Ouadid-Ahidouch
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7923
Schnipper, J, Kouba, S, Hague, F, Girault, A, Rybarczyk, P, Telliez, M-S, Guenin, S, Tebbakha, R, Sevestre, H, Ahidouch, A, Pedersen, S F & Ouadid-Ahidouch, H 2022, ' The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca 2+-Independent Manner ', International Journal of Molecular Sciences, vol. 23, no. 14, 7923 . https://doi.org/10.3390/ijms23147923
Schnipper, J, Kouba, S, Hague, F, Girault, A, Rybarczyk, P, Telliez, M-S, Guenin, S, Tebbakha, R, Sevestre, H, Ahidouch, A, Pedersen, S F & Ouadid-Ahidouch, H 2022, ' The TRPC1 Channel Forms a PI3K/CaM Complex and Regulates Pancreatic Ductal Adenocarcinoma Cell Proliferation in a Ca 2+-Independent Manner ', International Journal of Molecular Sciences, vol. 23, no. 14, 7923 . https://doi.org/10.3390/ijms23147923
Dysregulation of the transient receptor canonical ion channel (TRPC1) has been found in several cancer types, yet the underlying molecular mechanisms through which TRPC1 impacts pancreatic ductal adenocarcinoma (PDAC) cell proliferation are incomplet
Autor:
Maxime Guéguinou, Sajida Ibrahim, Jérôme Bourgeais, Alison Robert, Trayambak Pathak, Xuexin Zhang, David Crottès, Jacques Dupuy, David Ternant, Valérie Monbet, Roseline Guibon, Hector Flores-Romero, Antoine Lefèvre, Stéphanie Lerondel, Alain Le Pape, Jean-François Dumas, Philippe G. Frank, Alban Girault, Romain Chautard, Françoise Guéraud, Ana J. García-Sáez, Mehdi Ouaissi, Patrick Emond, Olivier Sire, Olivier Hérault, Gaëlle Fromont-Hankard, Christophe Vandier, David Tougeron, Mohamed Trebak, William Raoul, Thierry Lecomte
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, 2022, 79 (6), pp.article n° 284. ⟨10.1007/s00018-022-04311-4⟩
Cellular and Molecular Life Sciences, 2022, 79 (6), pp.article n° 284. ⟨10.1007/s00018-022-04311-4⟩
Colorectal cancer (CRC) is associated with high mortality worldwide and new targets are needed to overcome treatment resistance. Recent evidences highlight a role of the mitochondria calcium homeostasis in the development of CRC. In this context, we
Publikováno v:
Reviews of physiology, biochemistry and pharmacology. 181
In recent years, it has been shown that breast cancer consists not only of neoplastic cells, but also of significant alterations in the surrounding stroma or tumor microenvironment. These alterations are now recognized as a critical element for breas
Autor:
Alban, Girault, Marta, Peretti, Mehdi, Badaoui, Anaïs, Hémon, Hamid, Morjani, Halima, Ouadid-Ahidouch
Publikováno v:
Am J Cancer Res
It’s now clearly established that the tumor microenvironment participates to tumor development. Among the different actors contributing to these processes, ion channels, located at the cancer cell surface, play a major role. We recently demonstrate
Autor:
Morgane Caulet, Driffa Moussata, Chantal Barin-Le Guellec, Christophe Vandier, Aurélie Chantôme, Benjamin Anon, Clémence Perray, Bérenger Largeau, Alban Girault, Thierry Lecomte
Publikováno v:
Cancer Chemotherapy and Pharmacology. 82:149-157
Data suggest a role of the potassium channel SK3 (KCNN3 gene) in oxaliplatin-induced neurotoxicity (OIN). Length variations in the polymorphic CAG repeat of the KCNN3 gene may be associated with the risk of OIN. We performed patch-clamp experiments o