Altered innate immune profile in blood of systemic mastocytosis patients

Autor: Alba Pérez‐Pons, María Jara‐Acevedo, Ana Henriques, Paula Navarro‐Navarro, Andrés C. García‐Montero, Iván Álvarez‐Twose, Carlos E. Pedreira, Laura Sánchez‐Muñoz, Daniela Damasceno, Carolina Caldas, Javier I. Muñoz‐González, Almudena Matito, Juan Flores‐Montero, Oscar González‐López, Ignacio Criado, Andrea Mayado, Alberto Orfao

Publikováno v: Clinical and Translational Allergy, Vol 12, Iss 6, Pp n/a-n/a (2022)

Abstract Background Mast cells (MC) from systemic mastocytosis (SM) patients release MC mediators that lead to an altered microenvironment with potential consequences on innate immune cells, such as monocytes and dendritic cells (DC). Here we investi

Externí odkaz: https://doaj.org/article/dd7db6ae0e5a44aeb3411ba56ebf9c86

Frequency and prognostic impact of blood-circulating tumor mast cells in mastocytosis

Autor: Andrea Mayado, Iván Álvarez-Twose, María Jara-Acevedo, Ana Gabriela Henriques, Javier I. Muñoz-González, Laura Sánchez-Muñoz, Alba Pérez-Pons, Alberto Orfao, Carolina Caldas, Lidia Torres-Rivera, Andrés C. García-Montero, Almudena Matito

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Circulating tumor mast cells (CTMCs) have been identified in the blood of a small number of patients with advanced systemic mastocytosis (SM). However, data are limited about their frequency and prognostic impact in patients with MC activation syndro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5b2a0edf1a12390d4d7e4fa0c09eb7
https://doi.org/10.1182/blood.2021012694

Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study

Autor: Blanca Xicoy, Peter Valent, Juliana Schwaab, Khalid Shoumariyeh, Enrique Colado, Francesco Olivieri, Annette Schmitt-Graeff, Javier I. Muñoz-González, Andrés C. García-Montero, Georg Greiner, Iván Álvarez-Twose, Carlos Fernandez-Gimenez, Andreas Reiter, Jason Gotlib, María Jara-Acevedo, Ana Gabriela Henriques, Roberta Zanotti, Andrea Mayado, Alba Pérez-Pons, Cecelia Perkins, Wolfgang R. Sperr, Irene Luna, Mohamad Jawhar, Elvira Mora-Casterá, Maria-Helena Bañas, Ilaria Tanasi, Patrizia Bonadonna, Guillermo Martín-Sánchez, Laura Sánchez-Muñoz, Georgina Gener-Ricós, Amanda Nuñez-García, Manuel Jurado-Chacón, Leonor Senent, Justus Duyster, Carolina Caldas, Alberto Orfao

Publikováno v: Lancet Haematology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Digital.CSIC. Repositorio Institucional del CSIC
LANCET HAEMATOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

[Background]: Several risk stratification models have been proposed in recent years for systemic mastocytosis but have not been directly compared. Here we designed and validated a risk stratification model for progression-free survival (PFS) and over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87102b3cac8f78fab9b21cacc7454d2b
https://doi.org/10.1016/s2352-3026(20)30400-2

Monocyte subsets and serum inflammatory and bone-associated markers in monoclonal gammopathy of undetermined significance and multiple myeloma

Autor: Alberto Orfao, Alba Pérez-Pons, Noemi Puig, Paula Arana, Wouter B L van den Bossche, Brian G.M. Durie, Cristina Teodosio, Andrea Mayado, Alfonso Romero, Fernando Solano, Juan Flores-Montero, Jacques J.M. van Dongen, Julia Almeida, Luzalba Sanoja-Flores, Daniela Damasceno, Sergio Matarraz, Bruno Paiva

Publikováno v: Cancers, 13(6). MDPI
Cancers; Volume 13; Issue 6; Pages: 1454
Cancers, 13(6):1454, 1-18. Multidisciplinary Digital Publishing Institute (MDPI)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cancers
Cancers, Vol 13, Iss 1454, p 1454 (2021)

© 2021 by the authors.
Monocyte/macrophages have been shown to be altered in monoclonal gammopathy of undetermined significance (MGUS), smoldering (SMM) and active multiple myeloma (MM), with an impact on the disruption of the homeostasis of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598850a5f48b2c114d723786267bc1e1
http://hdl.handle.net/1887/3196560