Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alba Nin‐Hill"'
Autor:
Alexandre M. J. Gomila, Gonzalo Pérez-Mejías, Alba Nin-Hill, Alejandra Guerra-Castellano, Laura Casas-Ferrer, Sthefany Ortiz-Tescari, Antonio Díaz-Quintana, Josep Samitier, Carme Rovira, Miguel A. De la Rosa, Irene Díaz-Moreno, Pau Gorostiza, Marina I. Giannotti, Anna Lagunas
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Electron transfer between mitochondrial cytochrome c and subunit of cytochrome bc 1 can proceed at long distance. Here the authors investigate further the mechanism and show phosphorylation regulation of the interactions between the protein partners
Externí odkaz:
https://doaj.org/article/920316e566aa4c3caedde8b39a1e3048
Autor:
Sukanya Luang, Xavier Fernández-Luengo, Alba Nin-Hill, Victor A. Streltsov, Julian G. Schwerdt, Santiago Alonso-Gil, James R. Ketudat Cairns, Stéphanie Pradeau, Sébastien Fort, Jean-Didier Maréchal, Laura Masgrau, Carme Rovira, Maria Hrmova
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Barley β-d-glucan glucohydrolase is a glycoside hydrolase family 3 (GH3) enzyme critical for growth and development. Here the authors carryout mutagenesis, structural analyses and multi-scale molecular dynamics to examine the binding and conformatio
Externí odkaz:
https://doaj.org/article/4f9e72f63f2e475ebb7a7c53d7164632
Autor:
Anna Lagunas, Alejandra Guerra-Castellano, Alba Nin-Hill, Irene Díaz-Moreno, Miguel A. De la Rosa, Josep Samitier, Carme Rovira, Pau Gorostiza
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Electron transport chains rely on interactions between redox proteins, but the distance-dependence of the electron transfer rate through the solution is unknown. Here, the authors show that the current between two redox protein partners occurs at lon
Externí odkaz:
https://doaj.org/article/10ac0900b1754d54a485a9a162ceadd6
Publikováno v:
Essays in Biochemistry. 67:355-372
In silico modelling of proteins comprises a diversity of computational tools aimed to obtain structural, electronic, and/or dynamic information about these biomolecules, capturing mechanistic details that are challenging to experimental approaches, s
Autor:
Valentina Borlandelli, Zachary Armstrong, Alba Nin‐Hill, Jeroen D. C. Codée, Lluís Raich, Marta Artola, Carme Rovira, Gideon J. Davies, Herman S. Overkleeft
Publikováno v:
ChemMedChem
Degradation of the extracellular matrix (ECM) supports tissue integrity and homeostasis, but is also a key factor in cancer metastasis. Heparanase (HPSE) is a mammalian ECM-remodeling enzyme with β-D-endo-glucuronidase activity overexpressed in seve
Publikováno v:
Hansen, T, Nin-Hill, A, Codée, J D C, Hamlin, T A & Rovira, C 2022, ' Rational Tuning of the Reactivity of Three-Membered Heterocycle Ring Openings via S N 2 Reactions ', Chemistry-A European Journal, vol. 28, no. 60, e202201649 . https://doi.org/10.1002/chem.202201649
Chemistry-A European Journal, 28(60):e202201649. Wiley-VCH Verlag
Chemistry: a European Journal, 28(60):e202201649
Chemistry European Journal
Chemistry-A European Journal, 28(60):e202201649. Wiley-VCH Verlag
Chemistry: a European Journal, 28(60):e202201649
Chemistry European Journal
The development of small-molecule covalent inhibitors and probes continuously pushes the rapidly evolving field of chemical biology forward. A key element in these molecular tool compounds is the “electrophilic trap” that allows a covalent linkag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc82704bd9aff5cb359d917d888385c7
https://hdl.handle.net/1871.1/06a556c6-680f-464f-a10c-72b037300188
https://hdl.handle.net/1871.1/06a556c6-680f-464f-a10c-72b037300188
Publikováno v:
Current Opinion in Chemical Biology. 74:102282
Autor:
Nicholas G. S. McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin‐Hill, Daniël Linzel, Chihaya Yamada, Takatoshi Arakawa, Akihiro Ishiwata, Yukishige Ito, Gijsbert A. Marel, Jeroen D. C. Codée, Shinya Fushinobu, Herman S. Overkleeft, Carme Rovira, Gideon J. Davies
Publikováno v:
Angewandte Chemie. 133:5818-5822
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(60)
The development of small-molecule covalent inhibitors and probes continuously pushes the rapidly evolving field of chemical biology forward. A key element in these molecular tool compounds is the "electrophilic trap" that allows a covalent linkage wi
Autor:
Alba Nin-Hill, Carme Rovira
Publikováno v:
ACS Catalysis. 10:12091-12097
Krabbe disease is a neurodegenerative disorder related to misfunction of β-galactocerebrosidase (GALC), a glycosidase that cata-lyzes the cleavage of β-galactosidic bonds in glycosphingolipids. Her...