Hyperbranched polymers as non-viral vectors for gene delivery

Autor: Alazzo, Ali

The successful clinical translation of non-viral gene delivery systems has yet to be achieved due to the biological and technical obstacles to preparing a safe, potent and cost-effective vector. Hyperbranched polymers have emerged as promising candid

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.765514

DESIGN AND EVALUATION OF PROPOLIS-LOADED BUCCAL PATCHES.

Autor: ALAZZO, Ali, AL-NIMA, Amina Mudhafar, AL-QATTAN, Mohammed Nooraldeen

Publikováno v: Journal of Faculty of Pharmacy of Ankara University / Ankara Üniversitesi Eczacilik Fakültesi Dergisi; 2024, Vol. 48 Issue 3, p993-1003, 11p

LC-MS metabolomics comparisons of cancer cell and macrophage responses to methotrexate and polymer-encapsulated methotrexate

Autor: Al-Natour, Mohammad Ahmad, Alazzo, Ali, Ghaemmaghami, Amir M., Kim, Dong-Hyun, Alexander, Cameron

Publikováno v: In International Journal of Pharmaceutics: X December 2019 1

Investigating histidinylated highly branched poly(lysine) for siRNA delivery

Autor: Gurnani, Pratik, Alazzo, Ali, Gumus, Nurcan, Stolnik, Snjezana, Rahman, Ruman, Spriggs, Keith, Alexander, Cameron

The temporary silencing of disease-associated genes utilising short interfering RNA (siRNA) is a potent and selective route for addressing a wide range of life limiting disorders. However, the few clinically approved siRNA therapies rely on lipid bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::bc570f69c904a0890ac90d95cfec879c

Structural variations in hyperbranched polymers prepared via thermal polycondensation of lysine and histidine and their effects on DNA delivery.

Autor: Alazzo, Ali^1,2, Lovato, Tatiana¹, Collins, Hilary¹, Taresco, Vincenzo¹, Stolnik, Snjezana¹, Soliman, Mahmoud³, Spriggs, Keith¹, Alexander, Cameron¹ cameron.alexander@nottingham.ac.uk

Publikováno v: Journal of Interdisciplinary Nanomedicine. Jun2018, Vol. 3 Issue 2, p38-54. 17p.