Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Alayna E. Loiselle"'
Autor:
H. Mark Kenney, Chia-Lung Wu, Alayna E. Loiselle, Lianping Xing, Christopher T. Ritchlin, Edward M. Schwarz
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-20 (2022)
Abstract Background Lymphatic dysfunction exists in tumor necrosis factor transgenic (TNF-Tg) mice and rheumatoid arthritis (RA) patients. While joint-draining TNF-Tg popliteal lymphatic vessels (PLVs) have deficits in contractility during end-stage
Externí odkaz:
https://doaj.org/article/4e1ae8c2a72c4427a3e1df0e23045f60
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/09b4247ff8b94ed6849c613620e1afed
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Tendons are composed of a heterogeneous cell environment, with Scleraxis-lineage (ScxLin) cells being the predominant population. Although ScxLin cells are required for maintenance of tendon homeostasis, their functions during tendon healing are unkn
Externí odkaz:
https://doaj.org/article/d17363014ea74a64a7c50749c286391f
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Tendon injuries heal via scar tissue rather than regeneration. This healing response forms adhesions between the flexor tendons in the hand and surrounding tissues, resulting in impaired range of motion and hand function. Mechanistically, in
Externí odkaz:
https://doaj.org/article/930aa5bc24584e0e8f7273072e04ab6d
Publikováno v:
Bone Reports, Vol 10, Iss , Pp - (2019)
Type I and Type II Diabetes dramatically impair skeletal health. Altered Insulin Receptor (IR) signaling is a common feature of both diseases, and insulin has potent bone anabolic functions. Several previous studies have demonstrated that loss of IR
Externí odkaz:
https://doaj.org/article/b99f90e35c4d442fbb5903c3d25c1d39
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/c4741748dcd74ca4a5001f6000456862
Autor:
Katherine T Best, Antonion Korcari, Keshia E Mora, Anne EC Nichols, Samantha N Muscat, Emma Knapp, Mark R Buckley, Alayna E Loiselle
Publikováno v:
eLife, Vol 10 (2021)
Despite the requirement for Scleraxis-lineage (ScxLin) cells during tendon development, the function of ScxLin cells during adult tendon repair, post-natal growth, and adult homeostasis have not been defined. Therefore, we inducibly depleted ScxLin c
Externí odkaz:
https://doaj.org/article/42aa64b560f842b5bf477511668be005
Publikováno v:
Connective Tissue Research. 64:1-13
Aging is a complex and progressive process where the tissues of the body demonstrate a decreased ability to maintain homeostasis. During aging, there are substantial cellular and molecular changes, with a subsequent increase in susceptibility to path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc20639426f58d1a57d080d41ef235d
https://doi.org/10.1080/03008207.2022.2102004
https://doi.org/10.1080/03008207.2022.2102004
Autor:
Jessica E Ackerman, Anne EC Nichols, Valentina Studentsova, Katherine T Best, Emma Knapp, Alayna E Loiselle
Publikováno v:
eLife, Vol 8 (2019)
Identification of pro-regenerative approaches to improve tendon healing is critically important as the fibrotic healing response impairs physical function. In the present study we tested the hypothesis that S100a4 haploinsufficiency or inhibition of
Externí odkaz:
https://doaj.org/article/1ffb29c4d1f24c7dac0c94373922909f
Publikováno v:
Tissue Engineering Part B: Reviews.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e87b2902e9ce55188f852f03a2a32f
https://doi.org/10.1089/ten.teb.2022.0188
https://doi.org/10.1089/ten.teb.2022.0188