Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alayna Caffrey"'
Autor:
Kelly M. Shepardson, Benjamin Schwarz, Kyle Larson, Rachelle V. Morton, John Avera, Kimberly McCoy, Alayna Caffrey, Ann Harmsen, Trevor Douglas, Agnieszka Rynda-Apple
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/c0d0e91da9d0443183322e9c08973f4a
Autor:
Robert J. Torphy, Yi Sun, Ronggui Lin, Alayna Caffrey-Carr, Yuki Fujiwara, Felix Ho, Emily N. Miller, Martin D. McCarter, Traci R. Lyons, Richard D. Schulick, Ross M. Kedl, Yuwen Zhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Immunologically cold tumours don’t respond to immune checkpoint blockade inhibition due to poor recruitment of anti-tumour T cells. Authors show here that melanoma-associated lymphatic endothelial cells express G Protein-Coupled Receptor 182 that s
Externí odkaz:
https://doaj.org/article/e28ef266f4f9432191d2ec9e4d7e33a0
Autor:
Marina E. Kirkland, McKenzie Stannard, Caitlin H. Kowalski, Dallas Mould, Alayna Caffrey-Carr, Rachel M. Temple, Brandon S. Ross, Lotus A. Lofgren, Jason E. Stajich, Robert A. Cramer, Joshua J. Obar
Publikováno v:
mSphere, Vol 6, Iss 6 (2021)
ABSTRACT Aspergillus fumigatus isolates display significant heterogeneity in growth, virulence, pathology, and inflammatory potential in multiple murine models of invasive aspergillosis. Previous studies have linked the initial germination of a funga
Externí odkaz:
https://doaj.org/article/a9d97d6657df4007937c146b431aced9
Autor:
Elizabeth A. Thompson, Patricia A. Darrah, Kathryn E. Foulds, Elena Hoffer, Alayna Caffrey-Carr, Sophie Norenstedt, Leif Perbeck, Robert A. Seder, Ross M. Kedl, Karin Loré
Publikováno v:
Cell Reports, Vol 28, Iss 5, Pp 1127-1135.e4 (2019)
Summary: Using non-human primates (NHPs), mice, and human primary cells, we found a role for interleukin-10 (IL-10) in the upregulation of the tissue-resident memory T cell (TRM) marker CD103. In NHPs, intravenous, but not subcutaneous, immunization
Externí odkaz:
https://doaj.org/article/8414394f6b7d4b949f761c63d98542d3
Autor:
Kelly M. Shepardson, Benjamin Schwarz, Kyle Larson, Rachelle V. Morton, John Avera, Kimberly McCoy, Alayna Caffrey, Ann Harmsen, Trevor Douglas, Agnieszka Rynda-Apple
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT Although viruses and viral capsids induce rapid immune responses, little is known about viral pathogen-associated molecular patterns (PAMPs) that are exhibited on their surface. Here, we demonstrate that the repeating protein subunit pattern
Externí odkaz:
https://doaj.org/article/bf3aeed89b554e81bd3b7e859806801e
Autor:
Kelly M Shepardson, Anupam Jhingran, Alayna Caffrey, Joshua J Obar, Benjamin T Suratt, Brent L Berwin, Tobias M Hohl, Robert A Cramer
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004378 (2014)
Hypoxia inducible factor 1α (HIF1α) is the mammalian transcriptional factor that controls metabolism, survival, and innate immunity in response to inflammation and low oxygen. Previous work established that generation of hypoxic microenvironments o
Externí odkaz:
https://doaj.org/article/4ec4164d03554a5692a1a6b58ab063dd
Autor:
Ross M. Kedl, Benjamin Willett, Zheming Xu, Jared Klarquist, Christopher A. Hunter, Andrew Getahun, Scott B. Thompson, Daniel L. Aldridge, Alayna Caffrey-Carr, Eric W. Cross
Publikováno v:
SSRN Electronic Journal.
The close relationship between B cells and CD4 T cells has been carefully studied, revealing a collaborative effort, where B cells promote the activation, differentiation, and expansion of CD4 T cells, while the so-called “helper” cells provide s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dc080f22e6e105296868d49df84e17a
https://doi.org/10.2139/ssrn.3844714
https://doi.org/10.2139/ssrn.3844714
Autor:
Marina E Kirkland Mitchell, Alayna Caffrey-Carr, McKenzie Stannard, Caitlin H Kowalski, Dallas L Mould, Rachel Temple, Robert A Cramer, Joshua J Obar
Publikováno v:
The Journal of Immunology. 204:82.14-82.14
Fungal infections are emerging global health threats, costing the United States $7.2 billion annually in health care costs, with Aspergillus fumigatus accounting for $1.2 billion of those costs, the highest for a single fungal species and tied with C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8bb2ea1ae56c48e34a3da9ac184aade
https://doi.org/10.4049/jimmunol.204.supp.82.14
https://doi.org/10.4049/jimmunol.204.supp.82.14
Autor:
Alayna Caffrey, Joshua J. Obar
Publikováno v:
Current opinion in microbiology. 32
Fungi encounter numerous stresses in a mammalian host, including the immune system, which they must adapt to in order to grow and cause disease. The host immune system tunes its response to the threat level posed by the invading pathogen. We discuss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff50a2241041c1c076614d8a662e6cd
https://pubmed.ncbi.nlm.nih.gov/27351354
https://pubmed.ncbi.nlm.nih.gov/27351354
Autor:
Arsa Thammahong, Amariliz Rivera, Julianne Zickovich, Kelly M. Shepardson, Vanessa Espinosa, Kimberly M. Hilmer, Joshua J. Obar, Christopher P. Watschke, Robert A. Cramer, Margaret M. Lehmann, Alayna Caffrey, Bridget M. Barker
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 11, Iss 1, p e1004625 (2015)
PLoS Pathogens, Vol 11, Iss 1, p e1004625 (2015)
Aspergillus fumigatus is a mold that causes severe pulmonary infections. Our knowledge of how A. fumigatus growth is controlled in the respiratory tract is developing, but still limited. Alveolar macrophages, lung resident macrophages, and airway epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3225316f9c10d4d965d99c3bdee4efbf
http://europepmc.org/articles/PMC4309569
http://europepmc.org/articles/PMC4309569