Using genetics to explore complement C5 as a druggable protein in periodontitis.

Autor: Alayash Z; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany., Baumeister SE; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany., Holtfreter B; Department of Restorative Dentistry, Periodontology, Endodontology, and Preventive and Pediatric Dentistry, University Medicine Greifswald, Greifswald, Germany., Kocher T; Department of Restorative Dentistry, Periodontology, Endodontology, and Preventive and Pediatric Dentistry, University Medicine Greifswald, Greifswald, Germany., Baurecht H; Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany., Ehmke B; Clinic for Periodontology and Conservative Dentistry, University of Münster, Münster, Germany., Reckelkamm SL; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany.; Clinic for Periodontology and Conservative Dentistry, University of Münster, Münster, Germany., Nolde M; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Oct 08; Vol. 15, pp. 1407431. Date of Electronic Publication: 2024 Oct 08 (Print Publication: 2024).

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Prognostic models for predicting clinical disease progression, worsening and activity in people with multiple sclerosis.

Autor: Reeve K; Epidemiology, Biostatistics and Prevention Institute, University of Zürich, Zurich, Switzerland., On BI; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany., Havla J; lnstitute of Clinical Neuroimmunology, Ludwig-Maximilians-Universität München, Munich, Germany., Burns J; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany.; Pettenkofer School of Public Health, Munich, Germany., Gosteli-Peter MA; University Library, University of Zurich, Zurich, Switzerland., Alabsawi A; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany., Alayash Z; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany.; Institute of Health Services Research in Dentistry, University of Münster, Muenster, Germany., Götschi A; Epidemiology, Biostatistics and Prevention Institute, University of Zürich, Zurich, Switzerland., Seibold H; IGDORE, Munich, Germany., Mansmann U; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Munich, Germany.; Pettenkofer School of Public Health, Munich, Germany., Held U; Epidemiology, Biostatistics and Prevention Institute, University of Zürich, Zurich, Switzerland.

Publikováno v: The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2023 Sep 08; Vol. 9. Cochrane AN: CD013606. Date of Electronic Publication: 2023 Sep 08.

Downregulation of interleukin 6 signaling might reduce the risk of periodontitis: a drug target Mendelian randomization study.

Autor: Nolde M; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany., Alayash Z; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany., Reckelkamm SL; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany., Kocher T; Department of Restorative Dentistry, Periodontology, Endodontology, and Preventive and Pediatric Dentistry, University Medicine Greifswald, Greifswald, Germany., Ehmke B; Clinic for Periodontology and Conservative Dentistry, University of Münster, Münster, Germany., Holtfreter B; Department of Restorative Dentistry, Periodontology, Endodontology, and Preventive and Pediatric Dentistry, University Medicine Greifswald, Greifswald, Germany., Baurecht H; Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany., Georgakis MK; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany.; Program in Medical and Population Genetics, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, United States., Baumeister SE; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Jun 05; Vol. 14, pp. 1160148. Date of Electronic Publication: 2023 Jun 05 (Print Publication: 2023).

Effect of interleukin-17 on periodontitis development: An instrumental variable analysis.

Autor: Baumeister SE; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany., Holtfreter B; Department of Restorative Dentistry, Periodontology, Endodontology, and Preventive and Pediatric Dentistry, University Medicine Greifswald, Greifswald, Germany., Lars Reckelkamm S; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany., Hagenfeld D; Clinic for Periodontology and Conservative Dentistry, University of Münster, Münster, Germany., Kocher T; Department of Restorative Dentistry, Periodontology, Endodontology, and Preventive and Pediatric Dentistry, University Medicine Greifswald, Greifswald, Germany., Alayash Z; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany., Ehmke B; Clinic for Periodontology and Conservative Dentistry, University of Münster, Münster, Germany., Baurecht H; Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany., Nolde M; Institute of Health Services Research in Dentistry, University of Münster, Münster, Germany.

Publikováno v: Journal of periodontology [J Periodontol] 2023 May; Vol. 94 (5), pp. 616-621. Date of Electronic Publication: 2023 Jan 30.