Ramucirumab with cisplatin and fluoropyrimidine as first-line therapy in patients with metastatic gastric or junctional adenocarcinoma (RAINFALL): a double-blind, randomised, placebo-controlled, phase 3 trial.

Autor: Fuchs CS; Yale Cancer Center, Smilow Cancer Hospital, New Haven, CT, USA. Electronic address: charles.fuchs@yale.edu., Shitara K; National Cancer Center Hospital East, Kashiwa, Japan., Di Bartolomeo M; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Lonardi S; Istituto Oncologico Veneto-IRCCS, Padova, Italy., Al-Batran SE; Institute of Clinical Cancer Research at Krankenhaus Nordwest, UCT-University Cancer Center, Frankfurt, Germany., Van Cutsem E; University Hospitals Gasthuisberg, Leuven and KULeuven, Belgium., Ilson DH; Memorial Sloan Kettering Cancer Center, New York, NY, USA., Alsina M; Vall d'Hebron University Hospital and Institute of Oncology, Barcelona, Spain., Chau I; Royal Marsden Hospital, Sutton, Surrey, United Kingdom., Lacy J; Yale Cancer Center, Smilow Cancer Hospital, New Haven, CT, USA., Ducreux M; Gustave Roussy Cancer Centre, Grand Paris, Villejuif, France; Université Paris-Saclay, France., Mendez GA; Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina., Alavez AM; Center for Clinical Care and Research in Oncology, Merida, Yucatan, Mexico., Takahari D; The Cancer Institute Hospital of JFCR, Tokyo, Japan., Mansoor W; The Christie NHS Foundation Trust, Manchester, UK., Enzinger PC; Dana-Farber Cancer Institute, Boston, MA, USA., Gorbounova V; N N Blokhin Russian Cancer Research Center, Moscow, Russia., Wainberg ZA; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Hegewisch-Becker S; HOPE-Practice for Oncology, Hamburg, Germany., Ferry D; Eli Lilly and Company, New York City, NY, USA., Lin J; Eli Lilly and Company, Indianapolis, IN, USA., Carlesi R; Eli Lilly Italia, Florence, Italy., Das M; Eli Lilly and Company, Indianapolis, IN, USA., Shah MA; Weill Cornell Medical College, NY, USA; New York Presbyterian Hospital, New York, NY, USA.

Publikováno v: The Lancet. Oncology [Lancet Oncol] 2019 Mar; Vol. 20 (3), pp. 420-435. Date of Electronic Publication: 2019 Feb 01.