Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alastair Morgan Mackay"'
Publikováno v:
Experimental Hematology. 36:1176-1185
Objective Bone marrow stromal cells (MSC) are multipotent adult stem cells that have emerged as promising candidates for cell therapy in disorders including cardiac infarction, stroke, and spinal cord injury. While harvesting methods used by differen
Autor:
Min S. Kim, Vladimir Isachenko, Fred Levine, Alastair Morgan Mackay, Ayub G.-M. I. Lulat, Igor I. Katkov, Evgenia Isachenko
Publikováno v:
International Journal of Refrigeration. 29:346-357
Cells held in a liquid milieu undergo processes that cause progressive loss of viability. To prevent such degradation, cells need to be placed in conditions that essentially stop all chemical reactions for the duration of the time of storage. Because
Publikováno v:
Blood. 104:3410-3413
Magnetic resonance (MR) tracking of magnetically labeled cells is a relatively new technique to noninvasively determine the biodistribution and migration of transplanted or transfused stem cells in vivo.[1][1] The recent paper by Arbab et al[2][2] re
Autor:
Linda Howard, Birgit Neuhuber, Lisa Kostura, Itzhak Fischer, Alastair Morgan Mackay, Gianluca Gallo
Publikováno v:
Journal of Neuroscience Research. 77:192-204
Bone marrow stromal cells (MSC), which represent a population of multipotential mesenchymal stem cells, have been reported to undergo rapid and robust transformation into neuron-like phenotypes in vitro following treatment with chemical induction med
Autor:
Ronald Hoffman, Robert Dodds, Randell G. Young, Julius V. Turian, Carrington Cobbs, Alastair Morgan Mackay, Prasad Alur, Steven M. Devine, Michael P. Archambault, Jade Borneman, Amelia Bartholomew, Wenxin Pang, Nadim Mahmud, Padmavathy Vanguri
Publikováno v:
Experimental Hematology. 32:494-501
Objective The aim of this study was to examine the effects of the route of administration [intrabone marrow (IBM) vs intravenous (IV)] and the role of conditioning with irradiation in optimizing mesenchymal stem cell (MSC) transplantation. Materials
Publikováno v:
NMR in Biomedicine. 17:513-517
Magnetic resonance (MR) tracking of superparamagnetic iron oxide (SPIO)-labeled cells is a relatively new technique to non-invasively determine the biodistribution and migration of transplanted stem cells. A number of studies have recently reported e
Autor:
Diana Buyaner, Ronald Hoffman, Mandy Siatskas, Wayne Hardy, Nadim Mahmud, Sheila Patil, Cord Sturgeon, Alastair Morgan Mackay, Karen Ferrer, Joseph D. Mosca, Mary Nelson, Annemarie Moseley, Robert J. Deans, Steven M. Devine, Amelia Bartholomew
Publikováno v:
Human Gene Therapy. 12:1527-1541
Human mesenchymal stem cells (MSCs) are capable of differentiating into multiple mesenchymal lineages including chondrocytes, osteocytes, adipocytes, and marrow stromal cells. Using a nonhuman primate model, we evaluated nonhuman primate MSCs as targ
Autor:
Stephanie R. Oppenheimer, Jason Brunnabend, Iskren Puhlev, Alastair Morgan Mackay, Stephen L. Gordon, Fred Levine
Publikováno v:
Cryobiology. 43(2)
As cell therapies advance from research laboratories to clinical application, there is the need to transport cells and tissues across long distances while maintaining cell viability and function. Currently cells are successfully stored and shipped un
Autor:
Robin Douglas, Donald William Jr. Ward Road Simonetti, Stephen C. Beck, Stewart Craig, Daniel R. Marshak, Joseph D. Mosca, Mark Aaron Moorman, Mark F. Pittenger, Alastair Morgan Mackay, Rama K. Jaiswal
Publikováno v:
Science (New York, N.Y.). 284(5411)
Human mesenchymal stem cells are thought to be multipotent cells, which are present in adult marrow, that can replicate as undifferentiated cells and that have the potential to differentiate to lineages of mesenchymal tissues, including bone, cartila
Autor:
Stephen C. Beck, Alastair Morgan Mackay, Mark F. Pittenger, Clinton O. Chichester, Frank Barry, J. Mary Murphy
Publikováno v:
Tissue engineering. 4(4)
In the adult human, mesenchymal stem cells (MSCs) resident in bone marrow retain the capacity to proliferate and differentiate along multiple connective tissue lineages, including cartilage. In this study, culture-expanded human MSCs (hMSCs) of 60 hu