Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alastair Magness"'
Autor:
Alastair Magness, Emma Colliver, Katey S. S. Enfield, Claudia Lee, Masako Shimato, Emer Daly, David A. Moore, Monica Sivakumar, Karishma Valand, Dina Levi, Crispin T. Hiley, Philip S. Hobson, Febe van Maldegem, James L. Reading, Sergio A. Quezada, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The growing scale and dimensionality of multiplexed imaging require reproducible and comprehensive yet user-friendly computational pipelines. TRACERx-PHLEX performs deep learning-based cell segmentation (deep-imcyto), automated cell-type ann
Externí odkaz:
https://doaj.org/article/f61b4b8bd2f54cbd9679706490019396
Autor:
Helena Coggan, Clare E. Weeden, Philip Pearce, Mohit P. Dalwadi, Alastair Magness, Charles Swanton, Karen M. Page
Publikováno v:
Royal Society Open Science, Vol 11, Iss 7 (2024)
Mutations in the epidermal growth factor receptor (EGFR) are common in non-small cell lung cancer (NSCLC), particularly in never-smoker patients. However, these mutations are not always carcinogenic, and have recently been reported in histologically
Externí odkaz:
https://doaj.org/article/66b04cbe687f41668f6288b2cb3af1b2
Autor:
Charles Swanton, William Hill, Emilia Lim, Claudia Lee, Clare Weeden, Marcellus Augustine, Kezhong Chen, Feng-Che Kuan, Fabio Marongiu, Edward Evans, David Moore, Felipe Rodrigues, Febe van Maldegem, Jesse Boumelha, Selvaraju Veeriah, Andrew Rowan, Cristina Naceur-Lombardelli, Takahiro Karasaki, Monica Sivakumar, Deborah Caswell, Ai Nagano, Min Hyung Ryu, Ryan Huff, Shijia Li, Alastair Magness, Alejandro Suarez-Bonnet, Simon Priestnall, Margreet Lüchtenborg, Katrina Lavelle, Joanna Pethick, Steven Hardy, Fiona McRonald, Meng-Hung Lin, Clara Troccoli, Moumita Ghosh, York Miller, Daniel Merrick, Robert Keith, Maise Al Bakir, Chris Bailey, Lao Saal, Yilun Chen, Anthony George, Chris Abbosh, Nnennaya Kanu, Se-Hoon Lee, Nicholas McGranahan, Chistine Berg, Eva Grönroos, Julian Downward, Tyler Jacks, Christopher Carlsten, Ilaria Malanchi, Allan Hackshaw, Kevin Litchfield, Mariam Jamal-Hanjani, James DeGregori
Environmental carcinogenic exposures are major contributors to global disease burden yet how they promote cancer is unclear. Over 70 years ago, the concept of tumour promoting agents driving latent clones to expand was first proposed. In support of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59319a1fd502dd420ee185fca9f68dc0
https://doi.org/10.21203/rs.3.rs-1770054/v1
https://doi.org/10.21203/rs.3.rs-1770054/v1
Autor:
Alastair Magness, Katey Enfield, Mihaela Angelova, Emma Colliver, Emer Daly, Kristiana Grigoriadis, Claudia Lee, Oriol Pich, Philip Hobson, Dina Levi, Takahiro Karasaki, David Moore, Julian Downward, Erik Sahai, Mariam Jamal-Hanjani, Charles Swanton, TRACERx Consortium
Publikováno v:
Cancer Research. 82:1926-1926
Introduction: High dimensional imaging approaches such as imaging mass cytometry (IMC) are becoming widely used in cancer research. Such methods allow simultaneous observation of many cell types and their functional states and can provide valuable sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0683008e6b0667ccd1e81d4461b72e8b
https://doi.org/10.1158/1538-7445.am2022-1926
https://doi.org/10.1158/1538-7445.am2022-1926
Autor:
Mihaela Angelova, Katey Enfield, Alastair Magness, Emma Colliver, Masako Shimato, Claudia Lee, David A. Moore, Febe Van Maldegem, Philip Hobson, Dina Levi, James L. Reading, Crispin T. Hiley, Julian Downward, Erik Sahai, Charles Swanton
Publikováno v:
Cancer Research. 82:6113-6113
Introduction. Studying cell-to-cell variation within the tumour’s native context is crucial for fully understanding tumour heterogeneity and its impact on disease progression and therapy response. Tumour cells and their surrounding stromal cells ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8db54e0b58ebcfe97a22dcdefa5fffd0
https://doi.org/10.1158/1538-7445.am2022-6113
https://doi.org/10.1158/1538-7445.am2022-6113