Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Alastair J. Strain"'
Autor:
Alastair J. Strain, Luca Fabris, Mario Strazzabosco, Rocio I.R. Macias, Massimiliano Cadamuro, Paolo Simioni, Jose J.G. Marin
Publikováno v:
Liver Cancer International. 3:5-16
Publikováno v:
Hepatoma Research. 9:14
Intrahepatic cholangiocarcinoma (iCCA) is a rare neoplasm of the bile ducts with a low survival rate, whose incidence is continuously increasing and is associated with a rich and varied tumor microenvironment (TME). Although the main mutations charac
Autor:
Alberto Lasagni, Massimiliano Cadamuro, Claudia Maria Radu, Arianna Calistri, Matteo Pilan, Clarissa Valle, Pietro Angelo Bonaffini, Adriana Vitiello, Sandro Sironi, Maria Grazia Alessio, Previtali Giulia, Michela Seghezzi, Andrea Gianatti, Mario Strazzabosco, Alastair J Strain, Elena Campello, Luca Spiezia, Giorgio Palu, Cristina Parolin, Aurelio Sonzogni, Paolo Simioni, Luca Fabris
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
European Journal of Clinical Investigation. 40:575-584
P>Background/aims Conflicting observations exist concerning the role of nuclear factor kappa B (NF kappa B) in alcoholic liver disease (ALD) in animal models. To date no studies have examined this aspect in human liver tissue. We here assessed cytoki
Publikováno v:
Journal of Hepatology. 43:687-695
BACKGROUND/AIMS: In vitro and animal data suggest that alcohol and hepatitis C virus (HCV) proteins might interfere with Stat3 signaling, a potential regulator of liver cell apoptosis and proliferation. METHODS: We assessed Stat3 expression, activity
Autor:
David Tosh, Alastair J. Strain
Publikováno v:
Journal of Hepatology. 42:S75-S84
Liver diseases affect approximately 17.5% of the population [1] with the most severe cases being treated by orthotopic transplantation. Liver transplantation has become almost a routine procedure with one-year survival rates exceeding 80% [2]. One al
Autor:
Alastair J. Strain, Stefan G. Hubscher
Publikováno v:
Hepatology. 41:439-442
Publikováno v:
The American journal of pathology, Vol. 162, no. 2, p. 587-596 (2003)
In rats, activation of the cytokine-inducible transcription factor signal transducer and activator of transcription 3 (Stat3) is impaired in the liver after ethanol administration. The aim was to examine Stat3 expression, localization, and activity i
Publikováno v:
The American Journal of Pathology. 160:1695-1703
The Jagged and Delta family of transmembrane proteins are ligands for Notch receptors, which control the proliferation and/or differentiation of many cell lineages. Expression and localization of these ligands in the adult human liver has not been fu