Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alastair Dg. Lawson"'
Autor:
Alex Macpherson, Maisem Laabei, Zainab Ahdash, Melissa A Graewert, James R Birtley, Monika-Sarah ED Schulze, Susan Crennell, Sarah A Robinson, Ben Holmes, Vladas Oleinikovas, Per H Nilsson, James Snowden, Victoria Ellis, Tom Eirik Mollnes, Charlotte M Deane, Dmitri Svergun, Alastair DG Lawson, Jean MH van den Elsen
Publikováno v:
eLife, Vol 10 (2021)
Bovines have evolved a subset of antibodies with ultra-long heavy chain complementarity determining regions that harbour cysteine-rich knob domains. To produce high-affinity peptides, we previously isolated autonomous 3–6 kDa knob domains from bovi
Externí odkaz:
https://doaj.org/article/11009d4406c0451a844e90851ac87e3f
Autor:
Susan J. Crennell, Charlotte M. Deane, Vladas Oleinikovas, Ben Holmes, Jean M. H. van den Elsen, Alastair Dg Lawson, James Snowden, Maisem Laabei, Sarah Robinson, Dmitri I. Svergun, Zainab Ahdash, James R. Birtley, Monika-Sarah E. D. Schulze, Victoria Ellis, Alex Macpherson, Melissa A. Graewert, Per H. Nilsson, Tom Eirik Mollnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5aac6f122017b049092e52978a26843
https://doi.org/10.7554/elife.63586.sa2
https://doi.org/10.7554/elife.63586.sa2
Autor:
Mark Jairaj, Emma Dave, Ralph Adams, Shauna West, Laura Griffin, Oliver Zaccheo, Sam Philip Heywood, David Paul Humphreys, Tom Ceska, Joanne E. Compson, Alastair Dg. Lawson, Terry Baker
Publikováno v:
mAbs
We generated an anti-albumin antibody, CA645, to link its Fv domain to an antigen-binding fragment (Fab), thereby extending the serum half-life of the Fab. CA645 was demonstrated to bind human, cynomolgus, and mouse serum albumin with similar affinit