Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alasdair J. Edgar"'
Autor:
Alasdair J Edgar
Publikováno v:
DNA Sequence. 18:235-241
Two new cDNAs, human GPR107 and murine GPR108, were cloned from mammalian lung that are members of a novel gene family encoding proteins that are predicted to have an amino-terminal hydrophobic signal peptide sequence, a long extracellular domain and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ba639d429ec014ab4e0d00fb02a022
https://doi.org/10.1080/10425170701207182
https://doi.org/10.1080/10425170701207182
Autor:
Alasdair J. Edgar, Julia M. Polak
Publikováno v:
Biochemical and Biophysical Research Communications. 292:617-625
We have cloned 3 novel murine cDNAs encoding proteins containing an alpha/beta hydrolase fold; a catalytic domain found in a very wide range of enzymes. These proteins belong to the prosite UPF0017 uncharacterized protein family and we have named the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee1c976a6d7cd85e11271d9f273cc37
https://doi.org/10.1006/bbrc.2002.6692
https://doi.org/10.1006/bbrc.2002.6692
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 25:119-124
To identify changes in gene expression associated with emphysema, we used differential display to compare RNA extracted from emphysematous lungs with that of unused donor tissues taken at the time of transplant. A differentially expressed sequence wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ba57ca6a0a09fb9c076667ccbdb052
https://doi.org/10.1165/ajrcmb.25.1.4417
https://doi.org/10.1165/ajrcmb.25.1.4417
Publikováno v:
Journal of Biomedical Materials Research. 55:151-157
The effect of the ionic products of Bioglass 45S5 dissolution on the gene-expression profile of human osteoblasts was investigated by cDNA microarray analysis of 1,176 genes. Treatment with the ionic products of Bioglass 45S5 dissolution increased th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0817661e7b0deb31a290983aa10e84d
https://doi.org/10.1002/1097-4636(200105)55:2<151::aid-jbm1001>3.0.co
https://doi.org/10.1002/1097-4636(200105)55:2<151::aid-jbm1001>3.0.co
Autor:
Alasdair J. Edgar, Julia M. Polak
Publikováno v:
Biochemical and Biophysical Research Communications. 277:622-630
In the yeast Saccharomyces cerevisiae, a membrane coat complex is required for endosome to Golgi retrograde transport. The vacuolar protein sorting proteins Vps29p, Vps35p, and Vps26p are required for pre-vacuolar/late endosome to Golgi retrieval of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233d991a35d464cb4678075aa09e7fcd
https://doi.org/10.1006/bbrc.2000.3727
https://doi.org/10.1006/bbrc.2000.3727
Autor:
Dieter C. Gruenert, Matilde R. Chacón, Anne E. Bishop, Thomas J. Evans, Alasdair J. Edgar, Julia M. Polak, Qing-Hai Meng
Publikováno v:
The Journal of Pathology. 190:126-132
The bronchial epithelium in cystic fibrosis (CF) expresses very low levels of the inducible form of nitric oxide synthase (iNOS). The product of iNOS, nitric oxide (NO), mediates anti-microbial effects and can reduce neutrophil sequestration in the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d23ecbfe891002a1b5ca729f0d1f8113
https://doi.org/10.1002/(sici)1096-9896(200002)190:2<126::aid-path500>3.0.co
https://doi.org/10.1002/(sici)1096-9896(200002)190:2<126::aid-path500>3.0.co
Autor:
Jonathan P. Bennett, Alasdair J. Edgar
Publikováno v:
Journal of Anatomy. 195:173-184
In mice a molecular motor of the myosin V class (designated myosin Va) is known to be the product of the dilute locus, where a mutation prevents melanosome transport in melanocytes. There is conflicting evidence about whether it has a role in dendrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb08bdd132dcf071fe14e7a8a2f4334
https://doi.org/10.1046/j.1469-7580.1999.19520173.x
https://doi.org/10.1046/j.1469-7580.1999.19520173.x
Autor:
Alasdair J Edgar
Publikováno v:
Journal of Muscle Research and Cell Motility. 11:323-330
BHK gelsolin migrated on non-denaturing 8-25% polyacrylamide gels with an apparent molecular mass of 80 kDa. In the absence of Ca2+ no complex formation occurred between BHK gelsolin and actin. In the presence of Ca2+ two complex species were found:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba658805b2ed18b3f27b367b76f9a64
https://doi.org/10.1007/bf01766670
https://doi.org/10.1007/bf01766670
Publikováno v:
Respiratory Research
Respiratory Research, Vol 7, Iss 1, p 1 (2006)
Respiratory Research, Vol 7, Iss 1, p 1 (2006)
Background To elucidate further the pathogenesis of sporadic, idiopathic pulmonary arterial hypertension (IPAH) and identify potential therapeutic avenues, differential gene expression in IPAH was examined by suppression subtractive hybridisation (SS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a89e76c66282f4407175fe6dc2b9aa0
http://hdl.handle.net/10044/1/29592
http://hdl.handle.net/10044/1/29592
Autor:
Alasdair J Edgar
Publikováno v:
BMC Genomics
BMC Genomics, Vol 6, Iss 1, p 32 (2005)
BMC Genomics, Vol 6, Iss 1, p 32 (2005)
Background There are three pathways of L-threonine catabolism. The enzyme L-threonine aldolase (TA) has been shown to catalyse the conversion of L-threonine to yield glycine and acetaldehyde in bacteria, fungi and plants. Low levels of TA enzymatic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479648536ceeeb6d50ca9000f06a35eb
https://pubmed.ncbi.nlm.nih.gov/15757516
https://pubmed.ncbi.nlm.nih.gov/15757516