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Structural transitions modulate the chaperone activities of Grp94.

Autor: Amankwah YS; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056.; Pelotonia Institute for Immuno-Oncology, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, OH 43210., Fleifil Y; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056., Unruh E; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056.; Cell, Molecular, and Structural Biology Graduate Program, Miami University, Oxford, OH 45056., Collins P; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056., Wang Y; Pelotonia Institute for Immuno-Oncology, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, OH 43210., Vitou K; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056., Bates A; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056., Obaseki I; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056., Sugoor M; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056., Alao JP; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056., McCarrick RM; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056., Gewirth DT; Hauptman-Woodward Medical Research Institute, Buffalo, NY 14203., Sahu ID; Natural Sciences Division, Campbellsville University, Campbellsville, KY 42718., Li Z; Pelotonia Institute for Immuno-Oncology, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, OH 43210., Lorigan GA; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056.; Cell, Molecular, and Structural Biology Graduate Program, Miami University, Oxford, OH 45056., Kravats AN; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056.; Cell, Molecular, and Structural Biology Graduate Program, Miami University, Oxford, OH 45056.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Mar 19; Vol. 121 (12), pp. e2309326121. Date of Electronic Publication: 2024 Mar 14.