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Autor:
Jasmine Nguyen, Alanr Burns, Haley O. Tucker, Benjamin Soibam, Tara L. Rasmussen, Suhujey Lopez, Nicolas Valenzuela, M. David Stewart, Ashley Benham, Harika Nagandla, Harry J. Wu, Robert J. Schwartz
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 9, Iss 3, Pp 347-359 (2016)
Disease Models & Mechanisms, Vol 9, Iss 3, Pp 347-359 (2016)
The Smyd1 gene encodes a lysine methyltransferase specifically expressed in striated muscle. Because Smyd1-null mouse embryos die from heart malformation prior to formation of skeletal muscle, we developed a Smyd1 conditional-knockout allele to deter