Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alanna Watson"'
Autor:
Stephanie A. Fox, Michael W.A. Chu, Linrui Guo, Fuyan Li, Brittany Balint, John Michael Arpino, Oula Akawi, Bob Kiaii, Caroline O'Neil, Jorge A. Wong, J. Geoffrey Pickering, Hao Yin, Alanna Watson, A. Dave Nagpal, Mackenzie A. Quantz
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Short leukocyte telomeres have been associated with adverse cardiovascular outcomes in population studies, but this relationship has not translated to patient care. The authors report a telomere length autologous r
Highlights • Short leukocyte telomeres have been associated with adverse cardiovascular outcomes in population studies, but this relationship has not translated to patient care. The authors report a telomere length autologous r
Autor:
Caroline O'Neil, Krista Hawrylyshyn, Sina Ghoreishi, Alanna Watson, Zengxuan Nong, J. Geoffrey Pickering, Hao Yin
Publikováno v:
Atherosclerosis Supplements. 32:113-114
Autor:
J. Geoffrey Pickering, Hao Yin, Zengxuan Nong, David W. Holdsworth, Caroline O'Neil, Robert Gros, Faran Vafaie, Alanna Watson, John-Michael Arpino, Michael W.A. Chu
Publikováno v:
Aging Cell
Collagen fibrils become resistant to cleavage over time. We hypothesized that resistance to type I collagen proteolysis not only marks biological aging but also drives it. To test this, we followed mice with a targeted mutation (Col1a1(r/r) ) that yi
Intrinsic directionality of migrating vascular smooth muscle cells is regulated by NAD+ biosynthesis
Autor:
Michael W. A. Chu, Victoria Thibert, Matthew J. Frontini, Eric van der Veer, Caroline O'Neil, J. Geoffrey Pickering, Hao Yin, Alanna Watson, Peter Szasz
Publikováno v:
Journal of Cell Science. 125:5770-5780
Summary Cell migration is central to tissue repair and regeneration but must proceed with precise directionality to be productive. Directional migration requires external cues but also depends on the extent to which cells can inherently maintain thei
Autor:
J. Geoffrey Pickering, Stephanie A. Fox, Caroline O'Neil, Hao Yin, Linrui Guo, Zengxuan Nong, Robert Gros, Oberdan Leo, Brittany Balint, Alanna Watson, Michael W.A. Chu
Publikováno v:
Circulation research. 120(12)
Rationale: The thoracic aortic wall can degenerate over time with catastrophic consequences. Vascular smooth muscle cells (SMCs) can resist and repair artery damage, but their capacities decline with age and stress. Recently, cellular production of n
Abstract 504: Telomere-based Assessment of Biological Age in Patients with Advanced Vascular Disease
Autor:
John-Michael Arpino, A. Dave Nagpal, Caroline O'Neil, Mackenzie A. Quantz, Stephanie A. Fox, Fuyan Li, J. Geoffrey Pickering, Alanna Watson, Michael W.A. Chu, Hao Yin, Oula Akawi, Bob Kiaii, Brittany Balint, Jorge A. Wong, L. Ray Guo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Introduction: Ascertaining the biological age of patients with advanced vascular disease could advance risk assessment and management. The extent to which telomeres shorten in leukocytes could be a marker of biological age because it reflects the acc
Publikováno v:
Archives of Dermatological Research. 301:307-317
We have examined coordinated integrin and growth factor regulation of primary keratinocyte migration mediated by phosphoinositide 3-kinase (PI3K) and mitogen-activated extracellular-regulated kinase (MEK)/extracellular signal-regulated kinase (ERK).
Autor:
Brittany Balint, Hao Yin, Zengxuan Nong, Stephanie Fox, Stephanie Rogers, Caroline O’Neil, Alanna Watson, John-Michael Arpino, Lindsay Chase, Michael M Chu, Geoffrey Pickering
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Individuals with a bicuspid aortic valve (BAV) are at increased risk for ascending aortic dilation and dissection. Loss of aortic medial smooth muscle cells (SMCs) and disruption of the extracellular matrix are well-recognized pathologies, but the un
Publisher Summary This chapter discusses one of the major barriers to renal regeneration, namely cell and tissue aging. Aging of the vasculature, a process that can profoundly limit functional repair and regeneration, will be emphasized. Molecular pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc8a0ac80421eb14a7c9fdd555712fd
https://doi.org/10.1016/b978-0-12-380928-5.10019-3
https://doi.org/10.1016/b978-0-12-380928-5.10019-3
Autor:
Anthony Atala, Walid Beghdadi, Ulrich Blank, Joseph V. Bonventre, Nica M. Borradaile, Philip Brudnicki, Qi Cao, G.A. Challen, Eric Daugas, Jeremy S. Duffield, Danilo Fliser, Jürgen Floege, Svetlana Gavrilov, Tammer Ghaly, Catherine Godson, Michael S. Goligorsky, Marc R. Hammerman, David C.H. Harris, Hisashi Hashimoto, Benjamin D. Humphreys, Barbara Imberti, Hye Ryoun Jang, Jaap A. Joles, Akio Kobayashi, Magda Kucia, Uta Kunter, Donald W. Landry, Laura Lasagni, Elena Lazzeri, Vincent Lee, Lilach O. Lerman, M.H. Little, Rui Liu, Vicente Mirabet, Matthieu Monge, Marina Morigi, Nance Beyer Nardi, Przemyslaw Nowacki, Kenji Osafune, J. Geoffrey Pickering, Glenn D. Prestwich, Hamid Rabb, Ton J. Rabelink, Janina Ratajczak, Mariusz Z. Ratajczak, Brian Ratliff, Giuseppe Remuzzi, Martin Rodriguez-Porcel, Paola Romagnani, Maarten B. Rookmaaker, Charles N. Serhan, Dong-Myung Shin, Lindolfo da Silva Meirelles, Pilar Solves, Florian E. Tögel, Marianne C. Verhaar, Yuko Wakamatsu, Yiping Wang, Alanna Watson, Christof Westenfelder, Christodoulos Xinaris, Shinya Yamanaka, Xiang-Yang Zhu, Anton Jan van Zonneveld
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ac686ad831baa308fae3ec2e3bf4e7
https://doi.org/10.1016/b978-0-12-380928-5.10032-6
https://doi.org/10.1016/b978-0-12-380928-5.10032-6