Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alanna Gabrielle Spiteri"'
Autor:
Duan Ni, Jian Tan, Paula Niewold, Alanna Gabrielle Spiteri, Gabriela Veronica Pinget, Dragana Stanley, Nicholas Jonathan Cole King, Laurence Macia
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Dietary fiber supports healthy gut bacteria and their production of short-chain fatty acids (SCFA), which promote anti-inflammatory cell development, in particular, regulatory T cells. It is thus beneficial in many diseases, including influenza infec
Externí odkaz:
https://doaj.org/article/a8b5ad3dc462415095b1621dcf72f0e4
Publikováno v:
Wishart, Claire L; Spiteri, Alanna G; Locatelli, Giuseppe; King, Nicholas J C (2023). Integrating transcriptomic datasets across neurological disease identifies unique myeloid subpopulations driving disease-specific signatures. GLIA, 71(4), pp. 904-925. Wiley-Blackwell 10.1002/glia.24314
Microglia and bone marrow-derived monocytes are key elements of central nervous system (CNS) inflammation, both capable of enhancing and dampening immune-mediated pathology. However, the study-specific focus on individual cell types, disease models o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebff6184a54d77098dadd621a2be4df
https://boris.unibe.ch/176034/1/Glia_-_2022_-_Wishart_-_Integrating_transcriptomic_datasets_across_neurological_disease_identifies_unique_myeloid.pdf
https://boris.unibe.ch/176034/1/Glia_-_2022_-_Wishart_-_Integrating_transcriptomic_datasets_across_neurological_disease_identifies_unique_myeloid.pdf
Autor:
Alanna Gabrielle Spiteri, Claire L. Wishart, Nicholas J. C. King, Giuseppe Locatelli, Roger Pamphlett
Publikováno v:
Spiteri, Alanna G; Wishart, Claire L; Pamphlett, Roger; Locatelli, Giuseppe; King, Nicholas J C (2022). Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function. Acta neuropathologica, 143(2), pp. 179-224. Springer-Verlag 10.1007/s00401-021-02384-2
Acta Neuropathologica
Acta Neuropathologica
In neurological diseases, the actions of microglia, the resident myeloid cells of the CNS parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive immune-mediated pathology. However, defining the precise roles of each ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95f12b1edacd502868a5c3ad160bf0e
https://doi.org/10.1007/s00401-021-02384-2
https://doi.org/10.1007/s00401-021-02384-2
Autor:
Iain L. Campbell, Rachel Louise Terry, Thomas M. Ashhurst, Claire L. Wishart, Nicholas J. C. King, Markus J. Hofer, Alanna Gabrielle Spiteri
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-24 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
BackgroundDifferentiating infiltrating myeloid cells from resident microglia in neuroinflammatory disease is challenging, because bone marrow-derived inflammatory monocytes infiltrating the inflamed brain adopt a ‘microglia-like’ phenotype. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae49962fb4459e1edf85045dbe644330
https://doaj.org/article/ebf58f4e1d3f4998b8f08e4ddf92213b
https://doaj.org/article/ebf58f4e1d3f4998b8f08e4ddf92213b
Autor:
Nicholas J. C. King, Diana Shinko, Alanna Gabrielle Spiteri, Thomas M. Ashhurst, Felix Marsh-Wakefield, Adrian L. Smith, Mark Read, Givanna H. Putri
Publikováno v:
Cytometry Part A. 101:237-253
As the size and complexity of high-dimensional (HD) cytometry data continue to expand, comprehensive, scalable, and methodical computational analysis approaches are essential. Yet, contemporary clustering and dimensionality reduction tools alone are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83960d837b1976f578b862c4061c5705
https://doi.org/10.1002/cyto.a.24350
https://doi.org/10.1002/cyto.a.24350
Autor:
Givanna H. Putri, Thomas M. Ashhurst, Diana Shinko, Felix Marsh-Wakefield, Nicholas J. C. King, Mark Read, Alanna Gabrielle Spiteri, Adrian L. Smith
As the size and complexity of high-dimensional cytometry data continue to expand, comprehensive, scalable, and methodical computational analysis approaches are essential. Yet, contemporary clustering and dimensionality reduction tools alone are insuf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a500e9da0f0e8b0d4b6c42be5fc3052
https://doi.org/10.1101/2020.10.22.349563
https://doi.org/10.1101/2020.10.22.349563
Autoimmunity is a significant health concern with diseases such as type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis, drastically increasing in prevalence over the last 30–40 years. The precise trigger for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d63e899ce09b335ab4110ba335b6bc7f
https://doi.org/10.1016/b978-0-12-812102-3.00021-x
https://doi.org/10.1016/b978-0-12-812102-3.00021-x