Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alanna G Spiteri"'
Autor:
Alanna G Spiteri, Nicholas J.C. King
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 6, Pp 1269-1270 (2023)
Externí odkaz:
https://doaj.org/article/a9f660f2fc7547a3a15f77a842e49842
Autor:
Yihan Wang, Shu Liu, Alanna G. Spiteri, Andrew Liem Hieu Huynh, Chenyin Chu, Colin L. Masters, Benjamin Goudey, Yijun Pan, Liang Jin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Several (inter)national longitudinal dementia observational datasets encompassing demographic information, neuroimaging, biomarkers, neuropsychological evaluations, and muti-omics data, have ushered in a new era of potential for integrating
Externí odkaz:
https://doaj.org/article/eefdc1e7f56e408da1410a2f95024c8a
Autor:
Alanna G. Spiteri, Tamara Suprunenko, Erin Cutts, Andrew Suen, Thomas M. Ashhurst, Barney Viengkhou, Nicholas J. C. King, Markus J. Hofer
Publikováno v:
Viruses, Vol 16, Iss 3, p 390 (2024)
CD8+ T cells are critical to the adaptive immune response against viral pathogens. However, overwhelming antigen exposure can result in their exhaustion, characterised by reduced effector function, failure to clear virus, and the upregulation of inhi
Externí odkaz:
https://doaj.org/article/26022dd0865c4e828fc5dc8f2712d9fb
Autor:
Alanna G. Spiteri, Duan Ni, Zheng Lung Ling, Laurence Macia, Iain L. Campbell, Markus J. Hofer, Nicholas J. C. King
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PLX5622 is a CSF-1R inhibitor and microglia-depleting reagent, widely used to investigate the biology of this central nervous system (CNS)-resident myeloid population, but the indirect or off-target effects of this agent remain largely unexplored. In
Externí odkaz:
https://doaj.org/article/5d28240282434c559993a2f7d3c82cd6
Autor:
Alanna G. Spiteri, Claire L. Wishart, Duan Ni, Barney Viengkhou, Laurence Macia, Markus J. Hofer, Nicholas J. C. King
Publikováno v:
Acta Neuropathologica Communications. 11
As the resident parenchymal myeloid population in the central nervous system (CNS), microglia are strategically positioned to respond to neurotropic virus invasion and have been implicated in promoting both disease resolution and progression in the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f8f19195c13684280b8220937dfbde1
https://doi.org/10.1186/s40478-023-01547-4
https://doi.org/10.1186/s40478-023-01547-4
Autor:
Gi Uk Jeong, Hyung-Jun Kwon, Wern Hann Ng, Xiang Liu, Hyun Woo Moon, Gun Young Yoon, Hye Jin Shin, In-Chul Lee, Zheng Lung Ling, Alanna G. Spiteri, Nicholas J. C. King, Adam Taylor, Ji Soo Chae, Chonsaeng Kim, Dae-Gyun Ahn, Kyun-Do Kim, Young Bae Ryu, Seong-Jun Kim, Suresh Mahalingam, Young-Chan Kwon
Publikováno v:
Nature Communications. 13
Although ocular manifestations are reported in patients with COVID-19, consensus on ocular tropism of SARS-CoV-2 is lacking. Here, we infect K18-hACE2 transgenic mice with SARS-CoV-2 using various routes. We observe ocular manifestation and retinal i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c72f7088209dbc87a443c2b520e40dd
https://doi.org/10.1038/s41467-022-35225-1
https://doi.org/10.1038/s41467-022-35225-1
Autor:
Jonathan D. Teo, Oana C. Marian, Alanna G. Spiteri, Madeline Nicholson, Huitong Song, Jasmine X. Y. Khor, Holly P. McEwen, Anjie Ge, Monokesh K. Sen, Laura Piccio, Jessica L. Fletcher, Nicholas J. C. King, Simon S. Murray, Jens C. Brüning, Anthony S. Don
Publikováno v:
GliaREFERENCES.
The sphingolipids galactosylceramide (GalCer), sulfatide (ST) and sphingomyelin (SM) are essential for myelin stability and function. GalCer and ST are synthesized mostly from C22-C24 ceramides, generated by Ceramide Synthase 2 (CerS2). To clarify th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd0aa8eae28e42f1e57fd6b417fb276
https://pubmed.ncbi.nlm.nih.gov/36583573
https://pubmed.ncbi.nlm.nih.gov/36583573
Autor:
Jonathan D Teo, Oana C Marian, Alanna G Spiteri, Madeline Nicholson, Huitong Song, Jasmine XY Khor, Holly P McEwen, Laura Piccio, Jessica L Fletcher, Nicholas JC King, Simon S Murray, Jens C Brüning, Anthony S Don
The sphingolipids galactosylceramide (GalCer), sulfatide (ST) and sphingomyelin (SM) are essential for myelin stability and function. GalCer and ST are synthesized mostly from C22-C24 ceramides, generated by Ceramide Synthase 2 (CerS2). To clarify th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e1391891c58ae3d3a01710b1ce6cb0
https://doi.org/10.1101/2022.05.29.493337
https://doi.org/10.1101/2022.05.29.493337
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::866e2df138a85c4138bb9011e8c9c529
https://doi.org/10.2139/ssrn.3970230
https://doi.org/10.2139/ssrn.3970230
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Inflammation of the brain parenchyma is characteristic of neurodegenerative, autoimmune, and neuroinflammatory diseases. During this process, microglia, which populate the embryonic brain and become a permanent sentinel myeloid population, are inexor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1fd5944b3e5eccff0a157df84258c10
http://europepmc.org/articles/PMC7752943
http://europepmc.org/articles/PMC7752943