Endothelin-1-mediated Drug Resistance in EGFR-mutant NSCLC

Autor: Pulido, Inés, Ollosi, Stephen, Aparisi, Salvador, Becker, Jeffrey H., Aliena-Valero, Alicia, Benet, Marta, Rodríguez, María L., López, Adrián, Tamayo-Torres, Eva, Chuliá-Peris, Lourdes, García-Cañaveras, Juan Carlos, Soucheray, Margaret, Dalheim, Annika V., Salom, Juan B., Qiu, Wei, Kaja, Simon, Fernández-Coronado, Javier Alcácer, Alandes, Sandra, Alcácer, Javier, Al-Shahrour, Fátima, Borgia, Jeffrey A., Juan, Oscar, Nishimura, Michael I., Lahoz, Agustín, Carretero, Julián, Shimamura, Takeshi

Publikováno v: Cancer Res

Progression on therapy in NSCLC is often evaluated radiographically; however, image-based evaluation of said therapies may not distinguish disease progression due to intrinsic tumor drug resistance or inefficient tumor penetration of the drugs. Here

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https://europepmc.org/articles/PMC7541638/

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Nicotinamide Riboside and Pterostilbene Cooperatively Delay Motor Neuron Failure in ALS SOD1 ^G93A Mice.

Autor: Obrador E; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain., Salvador R; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain., Marchio P; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain., López-Blanch R; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain., Jihad-Jebbar A; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain., Rivera P; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain., Vallés SL; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain., Banacloche S; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain., Alcácer J; Pathology Laboratory, Quirón Hospital, 46010, Valencia, Spain., Colomer N; Pathology Laboratory, Quirón Hospital, 46010, Valencia, Spain., Coronado JA; Pathology Laboratory, Quirón Hospital, 46010, Valencia, Spain., Alandes S; Pathology Laboratory, Quirón Hospital, 46010, Valencia, Spain., Drehmer E; Department of Health and Functional Valorization, Catholic University of San Vicente Martir, 46001, Valencia, Spain., Benlloch M; Department of Health and Functional Valorization, Catholic University of San Vicente Martir, 46001, Valencia, Spain., Estrela JM; Department of Physiology, Faculty of Medicine and Odontology, University of Valencia, 15 Av. Blasco Ibañez, 46010, Valencia, Spain. jose.m.estrela@uv.es.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2021 Apr; Vol. 58 (4), pp. 1345-1371. Date of Electronic Publication: 2020 Nov 10.