Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alana Vicente"'
Autor:
Alana Vicente, Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, Emma Groarke, Valentina Giudice, Jennifer Lotter, Xingmin Feng, Sachiko Kajigaya, Barbara Weinstein, Evette Barranta, Matthew J. Olnes, Ankur R. Parikh, Maher Albitar, Colin O. Wu, Ruba Shalhoub, Katherine R. Calvo, Danielle M. Townsley, Phillip Scheinberg, Cynthia E. Dunbar, Neal S. Young, Thomas Winkler
Publikováno v:
Haematologica, Vol 105, Iss 12 (2020)
Myelodysplastic syndromes (MDS) are a group of clonal myeloid disorders characterized by cytopenia and a propensity to develop acute myeloid leukemia (AML). The management of lower-risk (LR) MDS with persistent cytopenias remains suboptimal. Eltrombo
Externí odkaz:
https://doaj.org/article/d39465a6ea80433faa1359329e4d1aed
Autor:
Sachiko Kajigaya, Fernanda Gutierrez-Rodrigues, Nohad Masri, Rodrigo T. Calado, Marie Louise Coussa, Neal S. Young, Wassim Serhal, Nadine Jalkh, Eliane Chouery, Hussein Farhat, Carrie Diamond, Alana Vicente, Noha Bejjani, Fayez Abillama
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Hum Genet
Universidade de São Paulo (USP)
instacron:USP
Hum Genet
Phenotypic heterogeneity is often observed in patients with telomeropathies caused by pathogenic variants in telomere biology genes. However, the roles of recessive variants in these different phenotypes are not fully characterized. Our goal is to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21822e865c0d9442227088c4889885d1
Autor:
Maher Albitar, Fernanda Gutierrez-Rodrigues, Katherine R. Calvo, Valentina Giudice, Thomas Winkler, Phillip Scheinberg, Barbara Weinstein, Neal S. Young, Maria del Pilar Fernandez Ibanez, Cynthia E. Dunbar, Sachiko Kajigaya, Zhijie Wu, Danielle M. Townsley, Alana Vicente
Publikováno v:
Blood. 132:229-229
Eltrombopag (EPAG), a thrombopoietin receptor agonist, has been shown to improve hematopoiesis in patients with aplastic anemia (AA), but in MDS patients the effect of thrombopoietin mimetics in bone marrow function is still unclear. In this phase-2
Autor:
Diego V. Clé, Laura W. Dillon, Flavia S. Donaires, Neal S. Young, Fernanda Gutierrez-Rodrigues, Alana Vicente, André Pinto, Barbara A. Santana, Christopher S. Hourigan, James N. Cooper, Maria del Pilar Fernandez Ibanez, Rodrigo T. Calado, Sachiko Kajigaya, Danielle M. Townsley
Publikováno v:
Blood. 132:539-539
Telomerase reactivation by acquisition of mutations in the TERT promoter (TERTp) region is a mechanism of tumorigenesis. The most common TERTp mutations are located in positions -146, -124, and -57 upstream the initiation codon. In non-malignant dise