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of 4
pro vyhledávání: '"Alana MacDonald"'
Autor:
Yu-Jui Kung, Brandon Lam, Ssu-Hsueh Tseng, Alana MacDonald, Hsin-Fang Tu, Suyang Wang, John Lin, Ya Chea Tsai, T. C. Wu, Chien-Fu Hung
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-12 (2022)
Abstract Background For centuries, microbial-based agents have been investigated as a therapeutic modality for the treatment of cancer. In theory, these methods would be cheap to produce, broadly applicable in a wide array of cancer types, and could
Externí odkaz:
https://doaj.org/article/14e4a2b3d15f460e890051d6c0f95012
Autor:
Alana MacDonald, Brandon Lam, John Lin, Louise Ferrall, Yu Jui Kung, Ya Chea Tsai, T.-C. Wu, Chien-Fu Hung
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The phospholipid phosphatidylserine (PS) is naturally maintained on the cytoplasmic side of the plasma membrane. Independent of apoptosis, PS is redistributed to the surface of CD8 T cells in response to TCR-mediated activation. Annexin V (AnnV) is a
Externí odkaz:
https://doaj.org/article/6267ec4e7c5b4195b90c716ff716f756
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Interleukin 2 (IL-2) plays a fundamental role in both immune activation and tolerance and has revolutionized the field of cancer immunotherapy since its discovery. The ability of IL-2 to mediate tumor regression in preclinical and clinical settings l
Externí odkaz:
https://doaj.org/article/fb172ce1ca654f948f000f3fe9370909
Autor:
Rizwan Ahmed, Zahra Omidian, Adebola Giwa, Kusuma Ananth, kagan Ege Karakus, Mahamoud Aljack, Neha Majety, Angela Yang, Alana Macdonald, Sanjana Tyagi, Hao Zhang, Hamid Rabb, Chunfa Jie, Thomas Donner, Abdel Hamad
Publikováno v:
The Journal of Immunology. 206:21.03-21.03
PURPOSE: We have recently identified a previously unknown lymphocyte that is a dual expresser (DE) of productively rearranged and surface-expressed TCRαβ and BCR (surface immunoglobulin, Ig) (Ahmed et al, Cell, 2019: 177:11583). Importantly, a sing