Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alana Keyser"'
Autor:
Pia Steigler, Mukesh Chhiba, Veronica Francis, Alana Keyser, Deborah Abrahams, Willem Hanekom, Mpiko Ntsekhe, Thomas J. Scriba
Publikováno v:
Vaccine: X, Vol 11, Iss , Pp 100177- (2022)
Background: In the Investigation of the Management of Pericarditis (IMPI) randomized control, 2x2 factorial trial, Mycobacterium indicus pranii (MIP) immunotherapy, adjunctive corticosteroids or MIP combined with corticosteroids was compared to stand
Externí odkaz:
https://doaj.org/article/33ad3ecb40d44e7cadae047c7bba15b6
Autor:
Vinzeigh N. Leukes, Stephanus T. Malherbe, Andriette Hiemstra, Leigh A. Kotze, Kelly Roos, Alana Keyser, Dalene De Swardt, Andrea Gutschmidt, Gerhard Walzl, Nelita du Plessis
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Successful TB treatment is hampered by increasing resistance to the two most effective first-line anti-TB drugs, namely isoniazid and rifampicin, thus innovative therapies focused on host processes, termed host-directed therapies (HDTs), are promisin
Externí odkaz:
https://doaj.org/article/c412de5fcccf443887d1b48438fa8307
Autor:
April Kaur Randhawa, Muki S Shey, Alana Keyser, Blas Peixoto, Richard D Wells, Marwou de Kock, Lesedi Lerumo, Jane Hughes, Gregory Hussey, Anthony Hawkridge, Gilla Kaplan, Willem A Hanekom, Thomas R Hawn, South African Tuberculosis Vaccine Initiative Team
Publikováno v:
PLoS Pathogens, Vol 7, Iss 8, p e1002174 (2011)
The development of effective immunoprophylaxis against tuberculosis (TB) remains a global priority, but is hampered by a partially protective Bacillus Calmette-Guérin (BCG) vaccine and an incomplete understanding of the mechanisms of immunity to Myc
Externí odkaz:
https://doaj.org/article/28d80e4872fc46ada9936e6fa622d3e3
Autor:
Pia, Steigler, Mukesh, Chhiba, Veronica, Francis, Alana, Keyser, Deborah, Abrahams, Willem, Hanekom, Mpiko, Ntsekhe, Thomas J, Scriba
Publikováno v:
Vaccine: X. 11
In theParticipants with definite or probable TBP were randomly assigned to receive five injections ofImmunotherapy withConsistent with the lack of a significant clinical effect in the IMPI trial
Autor:
Lynn Morris, Francois Villinger, Rosamund Chapman, Gerald K. Chege, Alana Keyser, Craig H. Adams, Anna-Lise Williamson, Valerie Bekker
Publikováno v:
Viruses
Volume 13
Issue 3
Viruses, Vol 13, Iss 397, p 397 (2021)
Volume 13
Issue 3
Viruses, Vol 13, Iss 397, p 397 (2021)
Rhesus macaques can be readily infected with chimeric simian-human immunodeficiency viruses (SHIV) as a suitable virus challenge system for testing the efficacy of HIV vaccines. Three Chinese-origin rhesus macaques (ChRM) were inoculated intravenousl
Autor:
Julia Amsterdam, Alessandro Companie, Fajwa Opperman, Justin Shenje, Steven G. Reed, Elma Van Rooyen, Sandra Goliath, Julia Noble, Tom Rolf, Friedrich Thienemann, Ann Swarts, Rhea N. Coler, Amaryl Van Schalkwyk, Linda-Gail Bekker, Sarah Albertson, Alessandro Sette, Erica Smit, Angelique Mouton, Michele Tameris, Zachary K. Sagawa, Lebohang Makhethe, Yolandi Herselman, Aude Frevol, Yolundi Cloete, Simbarashe Mabwe, Nicole Bilek, Angelique Kany Kany Luabeya, Alana Keyser, Cecilia S. Lindestam Arlehamn, Andrew Fiore-Gartland, Tracey A. Day, Asma Toefy, Carolyn Jones, Thomas J. Scriba, Linda van der Merwe, Constance Schreuder, Natasja Botes, Susan Rossouw, Andreas H. Diacon, Humphrey Mulenga, Adam Penn-Nicholson, Devona Hofmeester, Sandra Kruger, Nelita du Plessis, Fan-Chi Hsu, Jill A. Ashman, Julie Vergara, Anna Marie Beckmann, Eunice Sinandile, Andre G. Loxton, Elisabeth Filander, Ashley Veldsman, Andrea Gutschmidt, Marwou de Kock, Leya Hassanally, Hadn Africa, Stuart Kahn, Yiwen Lu, Marcia Steyn, Timothy D. Reid, Gerhard Walzl, Gail Jacobs, Elize van der Riet, Mark Hatherill, Cynthia Ontong, Nambitha Quaqua, H. Geldenhuys
Publikováno v:
The Lancet. Respiratory medicine. 9(4)
Summary Background A therapeutic vaccine that prevents recurrent tuberculosis would be a major advance in the development of shorter treatment regimens. We aimed to assess the safety and immunogenicity of the ID93 + GLA-SE vaccine at various doses an
Publikováno v:
Immunity, Inflammation and Disease. 5:57-67
Introduction Studies show that B-cells, in addition to producing antibodies and antigen-presentation, are able to produce cytokines as well. These include regulatory cytokines such as IL-10 by regulatory B-cells. Furthermore, a rare regulatory subset
Autor:
Helen Mearns, Hennie D. Geldenhuys, Benjamin M. Kagina, Munyaradzi Musvosvi, Francesca Little, Frances Ratangee, Hassan Mahomed, Willem A. Hanekom, Søren T. Hoff, Morten Ruhwald, Ingrid Kromann, Peter Bang, Mark Hatherill, Peter Andersen, Thomas J. Scriba, Virginie Rozot, Deborah A. Abrahams, Katya Mauff, Erica Smit, Yolande Brown, E. Jane Hughes, Edward Makgotlho, Alana Keyser, Mzwandile Erasmus, Lebohang Makhethe, Hadn Africa, Charles Hopley, Marcia Steyn
Publikováno v:
Vaccine
Background Control of the tuberculosis epidemic requires a novel vaccine that is effective in preventing tuberculosis in adolescents, a key target population for vaccination against TB. Methods Healthy adolescents, stratified by M. tuberculosis -infe
Autor:
Elisa Nemes, Virginie Rozot, Hennie Geldenhuys, Nicole Bilek, Simbarashe Mabwe, Deborah Abrahams, Lebohang Makhethe, Mzwandile Erasmus, Alana Keyser, Asma Toefy, Yolundi Cloete, Frances Ratangee, Thomas Blauenfeldt, Morten Ruhwald, Gerhard Walzl, Bronwyn Smith, Andre G. Loxton, Willem A. Hanekom, Jason R. Andrews, Maria D. Lempicki, Ruth Ellis, Ann M. Ginsberg, Mark Hatherill, Thomas J. Scriba, Susan Rossouw, Carolyn Jones, Elisma Schoeman, Yolande Gregg, Elizabeth Beyers, Sandra Kruger, Helen Veltdsman, Sophie Keffers, Sandra Goliath, Mariana Mullins, Michele Tameris, Angelique Luabeya, Ashley Veldsman, Humphrey Mulenga, Angelique Hendricks, Fajwa Opperman, Elma Van Rooyen, Julia Noble, Samentra Braaf, Rose Ockhuis, Emerencia Vermeulen, Alessandro Companie, Xoliswa Kelepu, Maigan Ratangee, Abraham Pretorius, Henry Issel, Phumzile Langata, Ilse Davids, Roxanne Herling, Hadn Africa, Marcia Steyn, Lungisa Nkantso, Noncedo Xoyana, Bongani Diamond, Margareth Erasmus, Jane Hughes, Denise van der Westhuizen, Lydia Makunzi, Natasja Botes, Julia Amsterdam, Clive Maqubela, Portia Dlakavu, Pamela Mangala, Charmaine Abrahams, Petrus Tyambetyu, Diann Gempies, Cindy Elbring, Elizabeth Hamilton, Fadia Alexander, Sindile Wiseman Matiwane, Cashwin September, Christel Petersen, Yulande Herselman, Johanna Hector, Terence Esterhuizen, Lauren Mactavie, Elize van der Riet, Debbie Pretorius, Justin Shenje, Anne Swarts, Eunice Sinandile, Janelle Botes, Constance Schreuder, Jateel Kassiem, Onke Xasa, Boitumelo Mosito, Rodney Raphela, Denis Arendsen, Palesa Dolo, Elizabeth Filander, Hassan Mahomed, Fazlin Kafaar, Leslie Workman, Rodney Ehrlich, Sizulu Moyo, Sebastian Gelderbloem, Gregory Hussey
Publikováno v:
American journal of respiratory and critical care medicine. 196(5)
Conversion from a negative to positive QuantiFERON-TB test is indicative of Mycobacterium tuberculosis (Mtb) infection, which predisposes individuals to tuberculosis disease. Interpretation of serial tests is confounded by immunological and technical
Autor:
Nazma Mansoor, Hassan Mahomed, Sizulu Moyo, Adrian V. S. Hill, Willem A. Hanekom, Mark Hatherill, Ashley Veldsman, Sebastian Gelderbloem, Thomas J. Scriba, Alison M. Lawrie, Helen McShane, Linda van der Merwe, Nathaniel Brittain, Alana Keyser, Erica Smit, Michele Tameris, Gregory D. Hussey, Anthony Hawkridge, Fatima Isaacs
Modified vaccinia Ankara-expressing Ag85A (MVA85A) is a new tuberculosis (TB) vaccine aimed at enhancing immunity induced by BCG. We investigated the safety and immunogenicity of MVA85A in healthy adolescents and children from a TB endemic region, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565c078aba324398d9823dd7f136b1e3
https://doi.org/10.1002/eji.200939754
https://doi.org/10.1002/eji.200939754