Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alana H.T. Nguyen"'
Autor:
Maxwell E.R. Shafer, Alana H.T. Nguyen, Mathieu Tremblay, Sophie Viala, Mélanie Béland, Nicholas R. Bertos, Morag Park, Maxime Bouchard
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 1018-1031 (2017)
Summary: During prostate development, basal and luminal cell lineages are generated through symmetric and asymmetric divisions of bipotent basal cells. However, the extent to which spindle orientation controls division symmetry or cell fate, and the
Externí odkaz:
https://doaj.org/article/d2397bc13482462aaa49c687702b28a9
Current therapeutic strategies against Wilms' tumor (WT) reach 80% to 85% success rate. In spite of this, a remaining 15% to 20% of tumors relapse and are associated with increased metastasis and poor prognosis. To identify new regulators of WT progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e18e701446557e1d33989d311099f2e
https://doi.org/10.1158/1541-7786.c.6542143.v1
https://doi.org/10.1158/1541-7786.c.6542143.v1
Autor:
Christina Guo, Ines Figueiredo, Bora Gurel, Antje Neeb, George Seed, Mateus Crespo, Suzanne Carreira, Jan Rekowski, Lorenzo Buroni, Jon Welti, Denisa Bogdan, Lewis Gallagher, Adam Sharp, Maria D. Fenor de la Maza, Pasquale Rescigno, Daniel Westaby, Khobe Chandran, Ruth Riisnaes, Ana Ferreira, Susana Miranda, Bianca Calì, Andrea Alimonti, Silvia Bressan, Alana H.T. Nguyen, Michael M. Shen, Jessica E. Hawley, Aleksandar Obradovic, Charles G. Drake, Claudia Bertan, Chloe Baker, Nina Tunariu, Wei Yuan, Johann S. de Bono
Publikováno v:
European Urology. 83:e168-e169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61117cf7a84082997575dd153b394d5f
https://doi.org/10.1016/j.eururo.2023.03.005
https://doi.org/10.1016/j.eururo.2023.03.005
Autor:
Christina Guo, Ines Figueiredo, Bora Gurel, Antje Neeb, George Seed, Mateus Crespo, Suzanne Carreira, Jan Rekowski, Lorenzo Buroni, Jon Welti, Denisa Bogdan, Lewis Gallagher, Adam Sharp, Maria D. Fenor de la Maza, Pasquale Rescigno, Daniel Westaby, Khobe Chandran, Ruth Riisnaes, Ana Ferreira, Susana Miranda, Bianca Calì, Andrea Alimonti, Silvia Bressan, Alana H.T. Nguyen, Michael M. Shen, Jessica E. Hawley, Aleksandar Obradovic, Charles G. Drake, Claudia Bertan, Chloe Baker, Nina Tunariu, Wei Yuan, Johann S. de Bono
Publikováno v:
European urology.
B7-H3 is a cell surface immunomodulatory glycoprotein overexpressed in prostate cancers (PCs). Understanding its longitudinal expression at emergence of castration resistance and association with tumour genomics are critical to the development of and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8163c4fcdb1706ee72462ceb2e445347
https://pubmed.ncbi.nlm.nih.gov/36114082
https://pubmed.ncbi.nlm.nih.gov/36114082
Autor:
Samantha Conroy, Alana H.T. Nguyen
Publikováno v:
European Urology. 82:271-272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc2066ca840edd06d6e4fdc97ed1eb
https://doi.org/10.1016/j.eururo.2022.04.006
https://doi.org/10.1016/j.eururo.2022.04.006
Autor:
Nicholas Bertos, Sophie Viala, Mathieu Tremblay, Alana H.T. Nguyen, Mélanie Béland, Maxime Bouchard, Maxwell E.R. Shafer, Morag Park
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 8, Iss 4, Pp 1018-1031 (2017)
Stem Cell Reports, Vol 8, Iss 4, Pp 1018-1031 (2017)
Summary During prostate development, basal and luminal cell lineages are generated through symmetric and asymmetric divisions of bipotent basal cells. However, the extent to which spindle orientation controls division symmetry or cell fate, and the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adeff55dfafe5572b7db31937ff26fc
http://europepmc.org/articles/PMC5390093
http://europepmc.org/articles/PMC5390093
Autor:
Mathieu Tremblay, Katharina Haigh, Alana H.T. Nguyen, Ismaël Hervé Koumakpayi, Anne-Marie Mes-Masson, Fred Saad, Pier Paolo Pandolfi, Maxime Bouchard, Marilène Paquet, Jody J. Haigh
Publikováno v:
BASE-Bielefeld Academic Search Engine
Loss of the tumor suppressor PTEN is a common occurrence in prostate cancer. This aberration leads to the ectopic activation of the PI3K-Akt pathway, which promotes tumor growth. Here, we show that the transcription factor Gata3 is progressively lost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21433ac2e20371a9c6621b5522f66d9b
https://doi.org/10.1093/hmg/ddt088
https://doi.org/10.1093/hmg/ddt088
Autor:
Hidetaka Ishii, Mathieu Tremblay, Alana H.T. Nguyen, Tomoko Takano, Nathalie Lamarche-Vane, You Chi Tang, Yaned Gaitan, Sami Kamel Boualia, Richa Sharma, Lamine Aoudjit, Daniela Stanga, Silvia M. Vidal, Michael Marcotte, Katherine Stewart, Di Hu, Maxwell E.R. Shafer, Maxime Bouchard
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005785 (2016)
PLoS Genetics
PLoS Genetics
Rho family GTPases act as molecular switches regulating actin cytoskeleton dynamics. Attenuation of their signaling capacity is provided by GTPase-activating proteins (GAPs), including p190A, that promote the intrinsic GTPase activity of Rho proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d3850bed4741cbb83aa6b22cfd992f
https://doi.org/10.1371/journal.pgen.1005785
https://doi.org/10.1371/journal.pgen.1005785
Publikováno v:
Molecular cancer research : MCR. 7(6)
Current therapeutic strategies against Wilms' tumor (WT) reach 80% to 85% success rate. In spite of this, a remaining 15% to 20% of tumors relapse and are associated with increased metastasis and poor prognosis. To identify new regulators of WT progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b71277c35d03f68f93c5cbc6799fd1f
https://pubmed.ncbi.nlm.nih.gov/19531566
https://pubmed.ncbi.nlm.nih.gov/19531566
Publikováno v:
The international journal of biochemistrycell biology. 39(9)
Apoptosis has been shown to be associated with altered glycosylation patterns and biosynthesis of glycoproteins. A major cell surface receptor involved in the induction of apoptosis is Fas that is activated by binding Fas ligand but can also be activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e231d6360bdd8995f327dc72407460bd
https://pubmed.ncbi.nlm.nih.gov/17544837
https://pubmed.ncbi.nlm.nih.gov/17544837