Výsledky vyhledávání - "Alan-Shaun Wilkinson"

Akademický článek

Performance testing protocol for closed-system transfer devices used during pharmacy compounding and administration of hazardous drugs.

Autor: Alan-Shaun Wilkinson, Michael Charles Allwood, Colin Patrick Morris, Andrew Wallace, Rebecca Finnis, Ewelina Kaminska, Donata Stonkute, Maja Szramowska, Joe Miller, Ian Pengelly, Michael Hemingway

Publikováno v: PLoS ONE, Vol 13, Iss 10, p e0205263 (2018)

OBJECTIVES:The United States National Institute for Occupational Safety and Health (NIOSH) is developing a protocol to assess the containment performance of closed system transfer devices (CSTDs) when used for drug preparation (task 1) and administra

Externí odkaz: https://doaj.org/article/51288cf947cb4f128bff4f71213dd270

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Assessment of the stability of citrate-buffered piperacillin/tazobactam for continuous infusion when stored in two commercially available elastomeric devices for outpatient parenteral antimicrobial chemotherapy: a study compliant with the NHS Yellow Cover Document requirements

Autor: Conor, Jamieson, Laima, Ozolina, R Andrew, Seaton, Mark, Gilchrist, Tim, Hills, F, Drummond, Alan Shaun, Wilkinson, Alan-Shaun, Wilkinson

Publikováno v: European Journal of Hospital Pharmacy. 29:212-216

Objectives To investigate the effect of pH control through the use of a citrate-buffered saline diluent pH 7 on the degradation rate of piperacillin/tazobactam solutions for infusion and to determine if an extended shelf-life of up to 13 days fridge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb41284fcfe562b05389beccec38b42
https://doi.org/10.1136/ejhpharm-2020-002340

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Integrity performance assessment of a closed system transfer device syringe adaptor lock as a terminal closure for Luer-Lock syringes

Autor: Alan Shaun Wilkinson, Kate E Walker, Laima Ozolina, Romana Machníková, Andrew J Johnson, Navneet Bhogal, Kate Pegg

Publikováno v: European journal of hospital pharmacy : science and practice.

To investigate the container closure integrity of a closed system transfer device syringe adaptor lock in combination with disposable Luer-Lock syringes as the terminal closure device. The UK National Health Service (NHS) Pharmaceutical Quality Assur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc76bb21805fadf38503ed02907c5c4
https://pubmed.ncbi.nlm.nih.gov/35410874

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Assessment of ceftolozane/tazobactam stability in elastomeric devices and suitability for continuous infusion via outpatient parenteral antimicrobial therapy

Autor: Mark Gilchrist, Michael Charles Allwood, Laima Ozolina, R Andrew Seaton, Felicity Drummond, Conor Jamieson, Tim Hills, Mark Santillo, Alan-Shaun Wilkinson

Publikováno v: JAC-Antimicrobial Resistance

Objectives To investigate the stability of ceftolozane/tazobactam 5 mg/mL and 20 mg/mL solutions for infusion in two elastomeric devices: FOLFusor LV10 (Baxter Healthcare) and Easypump® II (B. Braun Medical Ltd) and determine if an extended shelf li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150d8101d309d69cd05fd9f3bdc9e51c
http://europepmc.org/articles/PMC8527844

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Assessment of the stability of citrate-buffered flucloxacillin for injection when stored in two commercially available ambulatory elastomeric devices: INfusor LV (Baxter) and Accufuser (Woo Young Medical): a study compliant with the NHS Yellow Cover Document (YCD) requirements

Autor: Michael Charles, Allwood, Donata, Stonkute, Andrew, Wallace, Alan-Shaun, Wilkinson, Tim, Hills, Conor, Jamieson, Andrew, Seaton

Publikováno v: European Journal of Hospital Pharmacy

Objectives To investigate the effect of pH and buffers on the degradation rate of flucloxacillin and to determine if flucloxacillin can be stabilised using a buffered diluent for up to 14 days when stored at 2°C–8°C including a 24-hour infusion p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a904d36646a17f3e0db3de7790fdb6
http://europepmc.org/articles/PMC7044701

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Investigation of meropenem stability after reconstitution: the influence of buffering and challenges to meet the NHS Yellow Cover Document compliance for continuous infusions in an outpatient setting

Autor: Andrew Wallace, Donata Stonkute, Conor Jamieson, Tim Hills, Alan-Shaun Wilkinson, Michael Charles Allwood

Publikováno v: European Journal of Hospital Pharmacy

Objectives To determine the influence of different buffers, pH and meropenem concentrations on the degradation rates of meropenem in aqueous solution during storage at 32°C, with the aim of developing a formulation suitable for 24-hour infusion in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213285e0a8b5d27cc80c16d964a54c19
https://pubmed.ncbi.nlm.nih.gov/32296506

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Performance testing protocol for closed-system transfer devices used during pharmacy compounding and administration of hazardous drugs

Autor: Andrew Wallace, Ewelina Kaminska, Michael Charles Allwood, Rebecca Finnis, Michael Hemingway, Ian Pengelly, Colin Morris, Alan-Shaun Wilkinson, Donata Stonkute, Joe Miller, Maja Szramowska

Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205263 (2018)

Objectives The United States National Institute for Occupational Safety and Health (NIOSH) is developing a protocol to assess the containment performance of closed system transfer devices (CSTDs) when used for drug preparation (task 1) and administra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcac6526eb426921a4efacccde088fc
https://pubmed.ncbi.nlm.nih.gov/30379831

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[Untitled]

Autor: Alan-Shaun Wilkinson, Anthony Mellersh

Publikováno v: Origins of Life and Evolution of the Biosphere. 30:3-7

Polyadenylic acid (Poly A) immobilised on silica gel stereoselectively binds L-lysine from dilute aqueous solution. When the resulting complex is suspended in an organic solvent and liquid ammonia added, lysinamide is formed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ba1f82bc1eaa655f718b5776c84e4ce
https://doi.org/10.1023/a:1006620421068

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Multiple Conformations of the Acylenzyme Formed in the Hydrolysis of Methicillin by Citrobacter freundii β-Lactamase: a Time-Resolved FTIR Spectroscopic Study

Autor: Alan-Shaun Wilkinson, Christopher W. Wharton, Malcolm G. P. Page, Simon Ward, Malgosia Kania

Publikováno v: Biochemistry. 38:3851-3856

Time-resolved infrared difference spectroscopy has been used to show that the carbonyl group of the acylenzyme reaction intermediate in the Citrobacter freundii beta-lactamase-catalyzed hydrolysis of methicillin can assume at least four conformations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd3ac31036ea8f4c81a88e3888223c9
https://doi.org/10.1021/bi990030i

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Hydrogen bonding and protein perturbation in β-lactam acyl-enzymes of Streptococcus pneumoniae penicillin-binding protein PBP2x

Autor: Roger S. Chittock, Alan-Shaun Wilkinson, Malcolm G. P. Page, Simon Ward, Barbara Mensch, Patrick Caspers, Christopher W. Wharton

Publikováno v: Biochemical Journal. 338:153-159

A soluble form of Streptococcus pneumoniae PBP2x, a molecular target of penicillin and cephalosporin antibiotics, has been expressed and purified. IR difference spectra of PBP2x acylated with benzylpenicillin, cloxacillin, cephalothin and ceftriaxone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::895e47e257f081fe0ada9e397a203e77
https://doi.org/10.1042/bj3380153

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